PMC:7795966 / 19812-20590 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7795966","sourcedb":"PMC","sourceid":"7795966","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7795966","text":"It is well known that several medical drugs can increase MetHb concentration in the blood as a side-effect [26,27]. A recent review reports the early recognition, pathophysiology, and management of methemoglobinemia in the intensive care unit [28]. Chloroquine is such a drug for which reports were published regarding induced methemoglobinemia due to its intake [29,30,31]. Both chloroquine and hydroxychloroquine (a derivative of chloroquine) are currently used to treat COVID-19, while debate is ongoing about their effectiveness and safety [32,33,34,35,36,37,38,39]. Moderately certain evidence suggests that hydroxychloroquine lacks efficacy in reducing short-term mortality in patients hospitalized with COVID-19 or at risk of hospitalization in outpatients with COVID-19.","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"683","span":{"begin":57,"end":62},"obj":"Gene"},{"id":"684","span":{"begin":683,"end":691},"obj":"Species"},{"id":"685","span":{"begin":249,"end":260},"obj":"Chemical"},{"id":"686","span":{"begin":380,"end":391},"obj":"Chemical"},{"id":"687","span":{"begin":396,"end":414},"obj":"Chemical"},{"id":"688","span":{"begin":432,"end":443},"obj":"Chemical"},{"id":"689","span":{"begin":613,"end":631},"obj":"Chemical"},{"id":"690","span":{"begin":198,"end":215},"obj":"Disease"},{"id":"691","span":{"begin":327,"end":344},"obj":"Disease"},{"id":"692","span":{"begin":473,"end":481},"obj":"Disease"},{"id":"693","span":{"begin":670,"end":679},"obj":"Disease"},{"id":"694","span":{"begin":710,"end":718},"obj":"Disease"},{"id":"695","span":{"begin":769,"end":777},"obj":"Disease"}],"attributes":[{"id":"A683","pred":"tao:has_database_id","subj":"683","obj":"Gene:3048"},{"id":"A684","pred":"tao:has_database_id","subj":"684","obj":"Tax:9606"},{"id":"A685","pred":"tao:has_database_id","subj":"685","obj":"MESH:D002738"},{"id":"A686","pred":"tao:has_database_id","subj":"686","obj":"MESH:D002738"},{"id":"A687","pred":"tao:has_database_id","subj":"687","obj":"MESH:D006886"},{"id":"A688","pred":"tao:has_database_id","subj":"688","obj":"MESH:D002738"},{"id":"A689","pred":"tao:has_database_id","subj":"689","obj":"MESH:D006886"},{"id":"A690","pred":"tao:has_database_id","subj":"690","obj":"MESH:D008708"},{"id":"A691","pred":"tao:has_database_id","subj":"691","obj":"MESH:D008708"},{"id":"A692","pred":"tao:has_database_id","subj":"692","obj":"MESH:C000657245"},{"id":"A693","pred":"tao:has_database_id","subj":"693","obj":"MESH:D003643"},{"id":"A694","pred":"tao:has_database_id","subj":"694","obj":"MESH:C000657245"},{"id":"A695","pred":"tao:has_database_id","subj":"695","obj":"MESH:C000657245"},{"subj":"683","pred":"source","obj":"LitCovid-PubTator"},{"subj":"684","pred":"source","obj":"LitCovid-PubTator"},{"subj":"685","pred":"source","obj":"LitCovid-PubTator"},{"subj":"686","pred":"source","obj":"LitCovid-PubTator"},{"subj":"687","pred":"source","obj":"LitCovid-PubTator"},{"subj":"688","pred":"source","obj":"LitCovid-PubTator"},{"subj":"689","pred":"source","obj":"LitCovid-PubTator"},{"subj":"690","pred":"source","obj":"LitCovid-PubTator"},{"subj":"691","pred":"source","obj":"LitCovid-PubTator"},{"subj":"692","pred":"source","obj":"LitCovid-PubTator"},{"subj":"693","pred":"source","obj":"LitCovid-PubTator"},{"subj":"694","pred":"source","obj":"LitCovid-PubTator"},{"subj":"695","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T37","span":{"begin":198,"end":215},"obj":"Phenotype"},{"id":"T38","span":{"begin":327,"end":344},"obj":"Phenotype"}],"attributes":[{"id":"A37","pred":"hp_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/HP_0012119"},{"id":"A38","pred":"hp_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/HP_0012119"},{"subj":"T37","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T159","span":{"begin":0,"end":115},"obj":"Sentence"},{"id":"T160","span":{"begin":116,"end":248},"obj":"Sentence"},{"id":"T161","span":{"begin":249,"end":374},"obj":"Sentence"},{"id":"T162","span":{"begin":375,"end":570},"obj":"Sentence"},{"id":"T163","span":{"begin":571,"end":778},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T159","pred":"source","obj":"LitCovid-sentences"},{"subj":"T160","pred":"source","obj":"LitCovid-sentences"},{"subj":"T161","pred":"source","obj":"LitCovid-sentences"},{"subj":"T162","pred":"source","obj":"LitCovid-sentences"},{"subj":"T163","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93ecaf","default":true},{"id":"LitCovid-PD-HP","color":"#ec9593"},{"id":"LitCovid-sentences","color":"#93aaec"}]}]}}