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PMC:7795856 / 34208-37646 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
611 1800-1822 Gene denotes Dipeptidyl peptidase-4 Gene:1803
612 2607-2610 Gene denotes Tα1 Gene:134864
613 2635-2638 Gene denotes Tα1 Gene:134864
614 2765-2782 Gene denotes Prothymosin alpha Gene:100506248
615 2906-2926 Gene denotes Ribosomal-protein-S5 Gene:6193
616 2788-2807 Gene denotes Parathyroid hormone Gene:5741
617 1792-1798 Gene denotes DPP-IV Gene:1803
618 1456-1469 Gene denotes serum albumin Gene:213
619 1590-1616 Species denotes Corynebacterium glutamicum Tax:1718
620 1653-1700 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
621 1872-1879 Species denotes E. coli Tax:562
622 2233-2238 Species denotes Human Tax:9606
623 2262-2267 Species denotes Human Tax:9606
624 2783-2786 Gene denotes PTH Gene:5741
625 1643-1651 Disease denotes COVID-19 MESH:C000657245
626 2011-2043 Disease denotes Glucose-dependent insulinotropic MESH:D018149
627 2182-2231 Disease denotes HBV Hepatitis B virus HCV Hepatitis C virus hGH MESH:D006509
628 2281-2323 Disease denotes HIV-1 Human immunodeficiency virus I iRGD MESH:D015658
629 2670-2672 Disease denotes PD MESH:D010300

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T23 2187-2196 Phenotype denotes Hepatitis http://purl.obolibrary.org/obo/HP_0012115
T24 2210-2219 Phenotype denotes Hepatitis http://purl.obolibrary.org/obo/HP_0012115
T25 2294-2310 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T209 0-15 Sentence denotes Acknowledgments
T210 16-229 Sentence denotes The authors wish to thank Nicole Däschlein, Hyun-Jin Kim and Rebecca Walser, all at XL-protein, for help in gene cloning and western blotting and Corinna Brandt and Stefan Achatz at TUM for performing MS analyses.
T211 230-353 Sentence denotes Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.
T212 355-375 Sentence denotes Author Contributions
T213 376-472 Sentence denotes Conceptualization, U.B. and A.S.; experimental work, U.B.; manuscript preparation, U.B. and A.S.
T214 473-549 Sentence denotes All authors have read and agreed to the published version of the manuscript.
T215 551-558 Sentence denotes Funding
T216 559-602 Sentence denotes This research received no external funding.
T217 604-640 Sentence denotes Institutional Review Board Statement
T218 641-779 Sentence denotes The study was conducted in compliance with applicable animal welfare regulations (Institutional Animal Care and Use Committee approval No.
T219 780-798 Sentence denotes 2020_ATRC/5999_F).
T220 799-1025 Sentence denotes The permission code for PK studies (PK, metabolism, and bioequivalence) was PE/EA/1374-5/2017 and the permitting authority was the Government Office for Pest County, Directorate of Food Chain Safety and Animal Health, Hungary.
T221 1027-1053 Sentence denotes Informed Consent Statement
T222 1054-1069 Sentence denotes Not applicable.
T223 1071-1098 Sentence denotes Data Availability Statement
T224 1099-1188 Sentence denotes The data presented in this study are available on request from the corresponding authors.
T225 1190-1211 Sentence denotes Conflicts of Interest
T226 1212-1278 Sentence denotes U.B. and A.S. are co-founders and shareholders of XL-protein GmbH.
T227 1279-1292 Sentence denotes Abbreviations
T228 1293-1312 Sentence denotes AEX Anion exchange
T229 1313-1337 Sentence denotes AP Alkaline phosphatase
T230 1338-1376 Sentence denotes aTc Anhydrotetracycline hydrochloride
T231 1377-1400 Sentence denotes AUC Area und the curve
T232 1401-1443 Sentence denotes BCIP 5-Bromo-4-chloro-3-indoxyl phosphate
T233 1444-1469 Sentence denotes BSA Bovine serum albumin
T234 1470-1490 Sentence denotes CEX Cation exchange
T235 1491-1504 Sentence denotes CL Clearance
T236 1505-1548 Sentence denotes Cmax Maximum (or peak) serum concentration
T237 1549-1580 Sentence denotes CNP C-type natriuretic peptide
T238 1581-1642 Sentence denotes CORYNEX Corynebacterium glutamicum protein expression system
T239 1643-1700 Sentence denotes COVID-19 Severe acute respiratory syndrome coronavirus 2
T240 1701-1752 Sentence denotes CTLA-4 Cytotoxic T-lymphocyte-associated protein 4
T241 1753-1770 Sentence denotes CV Column volume
T242 1771-1791 Sentence denotes DCs Dendritic cells
T243 1792-1822 Sentence denotes DPP-IV Dipeptidyl peptidase-4
T244 1823-1863 Sentence denotes ELISA Enzyme-linked immunosorbent assay
T245 1864-1900 Sentence denotes ESETEC E. coli secretion technology
T246 1901-1950 Sentence denotes ESI-MS Electrospray ionization mass spectrometry
T247 1951-1991 Sentence denotes FPLC Fast protein liquid chromatography
T248 1992-2005 Sentence denotes GCC Glucagon
T249 2006-2055 Sentence denotes GIP Glucose-dependent insulinotropic polypeptide
T250 2056-2086 Sentence denotes GLP-1 Glucagon-like peptide 1
T251 2087-2143 Sentence denotes GM-CSF Granulocyte-macrophage colony-stimulating factor
T252 2144-2181 Sentence denotes GSH γ-L-Glutamyl-L-cysteinyl-glycine
T253 2182-2204 Sentence denotes HBV Hepatitis B virus
T254 2205-2227 Sentence denotes HCV Hepatitis C virus
T255 2228-2253 Sentence denotes hGH Human growth hormone
T256 2254-2280 Sentence denotes hIFN-α Human interferon 1
T257 2281-2318 Sentence denotes HIV-1 Human immunodeficiency virus I
T258 2319-2373 Sentence denotes iRGD Internalizing arginylglycylaspartic acid peptide
T259 2374-2428 Sentence denotes K3-EDTA Tri-potassium ethylenediaminetetraacetic acid
T260 2429-2466 Sentence denotes MHC Major histocompatibility complex
T261 2467-2509 Sentence denotes MOPS 3-(N-morpholino)propanesulfonic acid
T262 2510-2537 Sentence denotes NBT Nitro blue tetrazolium
T263 2538-2567 Sentence denotes OD Optical density at 550 nm
T264 2568-2602 Sentence denotes PAS Proline/alanine-rich sequence
T265 2603-2638 Sentence denotes PAS-Tα1 N-terminally PASylated Tα1
T266 2639-2669 Sentence denotes PBS Phosphate-buffered saline
T267 2670-2690 Sentence denotes PD Pharmacodynamics
T268 2691-2715 Sentence denotes PEG Polyethylene glycol
T269 2716-2720 Sentence denotes p.i.
T270 2722-2736 Sentence denotes Post injection
T271 2737-2757 Sentence denotes PK Pharmacokinetics
T272 2758-2782 Sentence denotes ProTα Prothymosin alpha
T273 2783-2807 Sentence denotes PTH Parathyroid hormone
T274 2808-2840 Sentence denotes Q-TOF Quadrupole time of flight
T275 2841-2867 Sentence denotes RBS Ribosome-binding site
T276 2868-2899 Sentence denotes RGD Arginylglycylaspartic acid
T277 2900-2954 Sentence denotes RimJ Ribosomal-protein-S5-alanine N-acetyltransferase
T278 2955-2988 Sentence denotes RPC Reverse phase chromatography
T279 2989-3009 Sentence denotes RT Room temperature
T280 3010-3044 Sentence denotes SEC Size exclusion chromatography
T281 3045-3112 Sentence denotes SDS-PAGE Sodium dodecyl sulfate polyacrylamide gel electrophoresis
T282 3113-3145 Sentence denotes τ1/2α Half-life of distribution
T283 3146-3174 Sentence denotes τ1/2β Elimination half-life
T284 3175-3196 Sentence denotes Tα1 Thymosin alpha 1
T285 3197-3245 Sentence denotes Tα1-PAS C-terminally PASylated Thymosin alpha 1
T286 3246-3284 Sentence denotes tetp/o Tetracycline promoter/operator
T287 3285-3302 Sentence denotes Th T helper cell
T288 3303-3331 Sentence denotes tlpp Lipoprotein terminator
T289 3332-3359 Sentence denotes TLR-2 Toll-like receptor 1
T290 3360-3387 Sentence denotes TLR-9 Toll-like receptor 2
T291 3388-3413 Sentence denotes TMAE Trimethylaminoethyl
T292 3414-3438 Sentence denotes tmax Time to reach Cmax