PMC:7795856 / 283-780 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
19	365-368	Gene	denotes	Tα1	Gene:134864
21	372-388	Species	denotes	Escherichia coli	Tax:562
25	307-308	Chemical	denotes	N	MESH:D009584
26	324-328	Chemical	denotes	RimJ
32	44-52	Disease	denotes	COVID-19	MESH:C000657245
33	53-63	Disease	denotes	infections	MESH:D007239
34	68-74	Disease	denotes	cancer	MESH:D009369

Id	Subject	Object	Predicate	Lexical cue	hp_id
T4	68-74	Phenotype	denotes	cancer	http://purl.obolibrary.org/obo/HP_0002664

Id	Subject	Object	Predicate	Lexical cue
T5	76-239	Sentence	denotes	Manufacturing of this N-terminally acetylated 28-residue peptide is demanding, and its short plasma half-life limits in vivo efficacy and requires frequent dosing.
T6	240-403	Sentence	denotes	Here, we combined the PASylation technology with enzymatic in situ N-acetylation by RimJ to produce a long-acting version of Tα1 in Escherichia coli at high yield.