PMC:7784830 / 20004-21212 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7784830","sourcedb":"PMC","sourceid":"7784830","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7784830","text":"Name of the herb and technique employed, if any, to load to ODFs Reason for choosing/selecting the herb to formulate as an ODFs Polymer Plasticizer Method Key highlight(s) Ref.\nGinger extract Existing formulations (capsules and liquids) of ginger suffer with problems of wettability of contents and inaccuracy in dosing. Hydroxypropyl methylcellulose (HPMC) or maltodextrin or pullulan Polyethylene glycol (PEG) Solvent casting method (SCM) HPMC based ODFs were found to be ideal with low disintegration time and stable at high temperature [21]\nIndonesian herbal extracts of Phaleria macrocarpa and Zingiber officinale Selected based on the herbal extracts popularity, reproducibility and well established scientific support (clinical evidence) HPMC with carbomer 947p (or) hydroxypropyl cellulose (HPC) Glycerol SCM Stable ODFs were obtained and benzalkonium chloride was employed as a stabilizer and also for spreadability [92]\nFoeniculum officinalis extract –a HPMC Glycerol SCM Employed super disintegrating agent (sodium starch glycollate) to achieve low disintegration time of ODF [93]\nGarlic extract –a Hypromellose Glycerol SCM Menthol was used as a flavoring agent 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