PMC:7784829 / 27756-28418
Annnotations
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T6 | 287-293 | Phenotype | denotes | cancer | http://purl.obolibrary.org/obo/HP_0002664 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T300 | 0-229 | Sentence | denotes | Curcumin has earlier shown to have specific inhibitory effect on the NA activity in influenza virus (Chen et al., 2013; Richart et al., 2018) and modulating immune response to prevent injury to the lung tissue (Han et al., 2018). |
T301 | 230-378 | Sentence | denotes | Till date, Bis-demethoxy curcumin has shown to have anti-cancer and hepato-protective activities (Kumaravel et al., 2013; Rajagopalan et al., 2010). |
T302 | 379-459 | Sentence | denotes | This is the first time; it is predicted to have a potential anti-viral activity. |
T303 | 460-662 | Sentence | denotes | Therefore, these curcumin derivatives, which have been predicted to bind to the SARS-CoV-2 spike protein, could be explored as probable inhibitors of COVID-19 spike protein through experimental studies. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
751 | 551-556 | Gene | denotes | spike | Gene:43740568 |
752 | 619-624 | Gene | denotes | spike | Gene:43740568 |
753 | 84-99 | Species | denotes | influenza virus | Tax:11308 |
754 | 540-550 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
755 | 0-8 | Chemical | denotes | Curcumin | MESH:D003474 |
756 | 241-263 | Chemical | denotes | Bis-demethoxy curcumin | MESH:C034786 |
757 | 477-485 | Chemical | denotes | curcumin | MESH:D003474 |
758 | 287-293 | Disease | denotes | cancer | MESH:D009369 |
759 | 610-618 | Disease | denotes | COVID-19 | MESH:C000657245 |