PMC:7784829 / 25611-26386 JSONTXT

{"project":"LitCovid-sentences","denotations":[{"id":"T282","span":{"begin":513,"end":518},"obj":"Sentence"},{"id":"T283","span":{"begin":519,"end":573},"obj":"Sentence"},{"id":"T284","span":{"begin":574,"end":616},"obj":"Sentence"},{"id":"T285","span":{"begin":617,"end":645},"obj":"Sentence"},{"id":"T286","span":{"begin":646,"end":670},"obj":"Sentence"},{"id":"T287","span":{"begin":671,"end":698},"obj":"Sentence"},{"id":"T288","span":{"begin":699,"end":723},"obj":"Sentence"},{"id":"T289","span":{"begin":724,"end":750},"obj":"Sentence"},{"id":"T290","span":{"begin":751,"end":775},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" Abbreviations: WS—Water solubility (log mol/L), CP—Caco2 permeability (log Papp in 10-6 cm/s), IA—Human intestinal absorption (% Absorbed), SP—Skin permeability (log Kp),PI-1—P-glycoprotein I inhibitor, PI-2—P-glycoprotein II inhibitor, VD—Human volume ofdistribution (log L/kg), FU—Fraction unbound (human) (Fu), BBB—BBB permeability (logBB), CNS—CNS permeability (log PS), CI-1—CYP3A4 inhibitor, CI-2—CYP2C9 inhibitor,TC—Total clearance (log mL/min/kg), RS—Renal OCT2 (organic cation transporter 2) substrate. BHBC: 3-5-di-tert-butyl-4-hydroxybenzaldehyde curcumin, MNC: 4-methoxy-1-naphthaldehyde curcumin, BDMC: Bis-demethoxy curcumin, DMC: Demethoxy curcumin, FAC: Ferulic-acid curcumin, IBC: Ibuprofen curcumin, IVC: Isovanillin curcumin, SYC: Syringaldehyde curcumin."}

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