PMC:7784829 / 18716-19232 JSONTXT

{"project":"LitCovid-sentences","denotations":[{"id":"T198","span":{"begin":0,"end":516},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Molecular docking of Bis-demethoxy curcumin on SARS-CoV-2 spike protein receptor binding domain (6M0J). (A) 3D structure of SARS-CoV-2 spike protein RBD bound with ACE2 protein Macromolecule. (B) Binding Interaction of Bis-demethoxy curcumin with amino acid residue of spike protein RBD of SARS-CoV-2 (PDB ID-6M0J). (C) Superimposed binding mode of Bis-demethoxy curcumin, docked with SARS-CoV-2 spike protein RBD. (D) 2D representation of the binding interaction of Bis-demethoxy curcumin with SARS-CoV-2 spike RBD."}

{"project":"LitCovid-PubTator","denotations":[{"id":"519","span":{"begin":135,"end":140},"obj":"Gene"},{"id":"520","span":{"begin":164,"end":168},"obj":"Gene"},{"id":"521","span":{"begin":269,"end":274},"obj":"Gene"},{"id":"522","span":{"begin":396,"end":401},"obj":"Gene"},{"id":"523","span":{"begin":506,"end":511},"obj":"Gene"},{"id":"524","span":{"begin":47,"end":57},"obj":"Species"},{"id":"525","span":{"begin":124,"end":134},"obj":"Species"},{"id":"526","span":{"begin":290,"end":300},"obj":"Species"},{"id":"527","span":{"begin":385,"end":395},"obj":"Species"},{"id":"528","span":{"begin":495,"end":505},"obj":"Species"},{"id":"529","span":{"begin":58,"end":63},"obj":"Gene"},{"id":"530","span":{"begin":21,"end":43},"obj":"Chemical"},{"id":"531","span":{"begin":219,"end":241},"obj":"Chemical"},{"id":"532","span":{"begin":349,"end":371},"obj":"Chemical"},{"id":"533","span":{"begin":467,"end":489},"obj":"Chemical"}],"attributes":[{"id":"A519","pred":"tao:has_database_id","subj":"519","obj":"Gene:43740568"},{"id":"A520","pred":"tao:has_database_id","subj":"520","obj":"Gene:59272"},{"id":"A521","pred":"tao:has_database_id","subj":"521","obj":"Gene:43740568"},{"id":"A522","pred":"tao:has_database_id","subj":"522","obj":"Gene:43740568"},{"id":"A523","pred":"tao:has_database_id","subj":"523","obj":"Gene:43740568"},{"id":"A524","pred":"tao:has_database_id","subj":"524","obj":"Tax:2697049"},{"id":"A525","pred":"tao:has_database_id","subj":"525","obj":"Tax:2697049"},{"id":"A526","pred":"tao:has_database_id","subj":"526","obj":"Tax:2697049"},{"id":"A527","pred":"tao:has_database_id","subj":"527","obj":"Tax:2697049"},{"id":"A528","pred":"tao:has_database_id","subj":"528","obj":"Tax:2697049"},{"id":"A529","pred":"tao:has_database_id","subj":"529","obj":"Gene:43740568"},{"id":"A530","pred":"tao:has_database_id","subj":"530","obj":"MESH:C034786"},{"id":"A531","pred":"tao:has_database_id","subj":"531","obj":"MESH:C034786"},{"id":"A532","pred":"tao:has_database_id","subj":"532","obj":"MESH:C034786"},{"id":"A533","pred":"tao:has_database_id","subj":"533","obj":"MESH:C034786"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Molecular docking of Bis-demethoxy curcumin on SARS-CoV-2 spike protein receptor binding domain (6M0J). (A) 3D structure of SARS-CoV-2 spike protein RBD bound with ACE2 protein Macromolecule. (B) Binding Interaction of Bis-demethoxy curcumin with amino acid residue of spike protein RBD of SARS-CoV-2 (PDB ID-6M0J). (C) Superimposed binding mode of Bis-demethoxy curcumin, docked with SARS-CoV-2 spike protein RBD. (D) 2D representation of the binding interaction of Bis-demethoxy curcumin with SARS-CoV-2 spike RBD."}