| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T83 |
0-100 |
Sentence |
denotes |
The lack of ample effective and affordable medicines is one of the vexing challenges faced globally. |
| T84 |
101-244 |
Sentence |
denotes |
It is imperative to generate novel treatment strategies, however, fair pricing and quick access to medicines remain a massive global challenge. |
| T85 |
245-376 |
Sentence |
denotes |
Chronic shortages and rising demands for critical drugs affect patient community with many dying from easily curable diseases [24]. |
| T86 |
377-554 |
Sentence |
denotes |
To a large extent, present day drug development and discovery is controlled oftentimes by private entities which are driven by vested economic interests and boundary conditions. |
| T87 |
555-705 |
Sentence |
denotes |
This leads to the burden trickling down to patients, their families and carers either through lack of effective medicines or mounting financial costs. |
| T88 |
706-943 |
Sentence |
denotes |
Addressing these global issues is the need of the hour and a plausible solution could be devising new tools and technologies, novel methodological approaches, and infrastructural changes to streamline the drug discovery review processes. |
| T89 |
944-1081 |
Sentence |
denotes |
On the other hand, the desperate need for new effective drugs raises a concern over the efficacy of many of the currently marketed drugs. |
| T90 |
1082-1273 |
Sentence |
denotes |
A study examining efficacy of solid tumors therapies approved by the FDA between 2002 and 2014, found only 30 out of 71 therapies (42%) to have modest clinically meaningful improvements [25]. |
| T91 |
1274-1375 |
Sentence |
denotes |
Sluggish data sharing and irreproducibility of published research remains as another major challenge. |
| T92 |
1376-1528 |
Sentence |
denotes |
A 2016 survey of 1,576 researchers by the journal Nature found that over 70% of researchers have failed to reproduce other scientist’s experiments [26]. |
