PMC:7784824 / 9180-11045 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"224","span":{"begin":119,"end":127},"obj":"Species"},{"id":"225","span":{"begin":101,"end":109},"obj":"Disease"}],"attributes":[{"id":"A224","pred":"tao:has_database_id","subj":"224","obj":"Tax:9606"},{"id":"A225","pred":"tao:has_database_id","subj":"225","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The 14 serological assays listed in Table 1 were performed on each of the 23 sera from PCR confirmed COVID-19 positive patients and the 19 pre-pandemic/cross-reactive sera, according to the manufacturer’s instructions. Sensitivity and specificity were calculated for each test. We calculated both the overall sensitivity (day 2–18 after symptom onset) and the sensitivity of the two subgroups (day 2–7 and day 8–18), each time for IgM/A and IgG separately and for combined IgM/A and IgG testing.\nTable 1. Overview of the included assays\nTest Assay Company Antibody detection Recombinant antigen\nPoint-of-care test\nCorona Virus (COVID-19) Combined IgM/IgG Rapid Test Sol Scientifics IgM+IgG Not specified\nCOVID-19 IgG/igM Rapid Test Cassette Zhejiang ORIENT GENE Biotech IgM+IgG Spike + nucleocapsid protein\nWantai SARS-COV-2 Ab Rapid Test Beijing Wantai Biological Pharmacy Enterprise IgM+IgG (combined) Not specified\nCOVID-19 IgG/IgM RAPID TEST PRIMA PROFESSIONAL IgM+IgG Not specified\nDiagnostic Kit for IgG/IgM Antibody to SARS-CoV-2 WIZ BIOTECH IgM+IgG Not specified\nEnzyme-Linked Immunosorbent Assay (ELISA)\nAnti-SARS-CoV-2 ELISA (IgA) EUROIMMUN S1 Spike glycoprotein (S1domain)\nAnti-SARS-CoV-2 ELISA (IgG) EUROIMMUN IgG Spike glycoprotein (S1domain)\nNovel Coronavirus COVID-19 IgM ELISA Kit Epitope Diagnostics (EDI) IgM Not specified\nNovel Coronavirus COVID-19 IgG ELISA Kit Epitope Diagnostics (EDI) IgG Nucleocapsid protein\nSARS-CoV-2 IgM ELISA Kit Creative Diagnostics IgM Not specified\nSARS-CoV-2 IgG ELISA kit Creative Diagnostics IgG Not specified\nHuman Anti-2019 nCoV(N) IgG ELISA kit Finetest, Wuhan Fine Biotech Co., Ltd. IgG Spike glycoprotein (S1domain)\nChemiluminescent microparticle immunoassay (CMIA)\nSARS-CoV-2 IgG Abbott IgG Nucleocapsid protein\nChemiluminescence immunoassay (CLIA)\nLiaison SARS-CoV-2 S1/S2 IgG DiaSorin IgG S1 and S2 protein"}

{"project":"LitCovid-sentences","denotations":[{"id":"T91","span":{"begin":0,"end":218},"obj":"Sentence"},{"id":"T92","span":{"begin":219,"end":277},"obj":"Sentence"},{"id":"T93","span":{"begin":278,"end":495},"obj":"Sentence"},{"id":"T94","span":{"begin":496,"end":504},"obj":"Sentence"},{"id":"T95","span":{"begin":505,"end":536},"obj":"Sentence"},{"id":"T96","span":{"begin":537,"end":594},"obj":"Sentence"},{"id":"T97","span":{"begin":595,"end":613},"obj":"Sentence"},{"id":"T98","span":{"begin":614,"end":703},"obj":"Sentence"},{"id":"T99","span":{"begin":704,"end":806},"obj":"Sentence"},{"id":"T100","span":{"begin":807,"end":917},"obj":"Sentence"},{"id":"T101","span":{"begin":918,"end":986},"obj":"Sentence"},{"id":"T102","span":{"begin":987,"end":1070},"obj":"Sentence"},{"id":"T103","span":{"begin":1071,"end":1112},"obj":"Sentence"},{"id":"T104","span":{"begin":1113,"end":1183},"obj":"Sentence"},{"id":"T105","span":{"begin":1184,"end":1255},"obj":"Sentence"},{"id":"T106","span":{"begin":1256,"end":1340},"obj":"Sentence"},{"id":"T107","span":{"begin":1341,"end":1432},"obj":"Sentence"},{"id":"T108","span":{"begin":1433,"end":1496},"obj":"Sentence"},{"id":"T109","span":{"begin":1497,"end":1560},"obj":"Sentence"},{"id":"T110","span":{"begin":1561,"end":1637},"obj":"Sentence"},{"id":"T111","span":{"begin":1638,"end":1671},"obj":"Sentence"},{"id":"T112","span":{"begin":1672,"end":1721},"obj":"Sentence"},{"id":"T113","span":{"begin":1722,"end":1768},"obj":"Sentence"},{"id":"T114","span":{"begin":1769,"end":1805},"obj":"Sentence"},{"id":"T115","span":{"begin":1806,"end":1865},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The 14 serological assays listed in Table 1 were performed on each of the 23 sera from PCR confirmed COVID-19 positive patients and the 19 pre-pandemic/cross-reactive sera, according to the manufacturer’s instructions. Sensitivity and specificity were calculated for each test. We calculated both the overall sensitivity (day 2–18 after symptom onset) and the sensitivity of the two subgroups (day 2–7 and day 8–18), each time for IgM/A and IgG separately and for combined IgM/A and IgG testing.\nTable 1. Overview of the included assays\nTest Assay Company Antibody detection Recombinant antigen\nPoint-of-care test\nCorona Virus (COVID-19) Combined IgM/IgG Rapid Test Sol Scientifics IgM+IgG Not specified\nCOVID-19 IgG/igM Rapid Test Cassette Zhejiang ORIENT GENE Biotech IgM+IgG Spike + nucleocapsid protein\nWantai SARS-COV-2 Ab Rapid Test Beijing Wantai Biological Pharmacy Enterprise IgM+IgG (combined) Not specified\nCOVID-19 IgG/IgM RAPID TEST PRIMA PROFESSIONAL IgM+IgG Not specified\nDiagnostic Kit for IgG/IgM Antibody to SARS-CoV-2 WIZ BIOTECH IgM+IgG Not specified\nEnzyme-Linked Immunosorbent Assay (ELISA)\nAnti-SARS-CoV-2 ELISA (IgA) EUROIMMUN S1 Spike glycoprotein (S1domain)\nAnti-SARS-CoV-2 ELISA (IgG) EUROIMMUN IgG Spike glycoprotein (S1domain)\nNovel Coronavirus COVID-19 IgM ELISA Kit Epitope Diagnostics (EDI) IgM Not specified\nNovel Coronavirus COVID-19 IgG ELISA Kit Epitope Diagnostics (EDI) IgG Nucleocapsid protein\nSARS-CoV-2 IgM ELISA Kit Creative Diagnostics IgM Not specified\nSARS-CoV-2 IgG ELISA kit Creative Diagnostics IgG Not specified\nHuman Anti-2019 nCoV(N) IgG ELISA kit Finetest, Wuhan Fine Biotech Co., Ltd. IgG Spike glycoprotein (S1domain)\nChemiluminescent microparticle immunoassay (CMIA)\nSARS-CoV-2 IgG Abbott IgG Nucleocapsid protein\nChemiluminescence immunoassay (CLIA)\nLiaison SARS-CoV-2 S1/S2 IgG DiaSorin IgG S1 and S2 protein"}