PMC:7784786 / 2220-2768 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7784786","sourcedb":"PMC","sourceid":"7784786","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7784786","text":"CD6 is a membrane glycoprotein expressed primarily in mature, activated T cells. Ligand binding of CD6, increases events such as adhesion, activation, proliferation, differentiation and survival [3–6]. In addition, CD6 mediates interaction between T cells and antigen-presenting cells, contributing to the maturation of immune synapses [6]. CD6-mediated costimulation contributes to the maturation of a Th1 pattern in human T cells and preferentially promotes a pro-inflammatory response characterized by the secretion of TNF-α, IL-6 and IFN γ [7].","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"98","span":{"begin":0,"end":3},"obj":"Gene"},{"id":"99","span":{"begin":99,"end":102},"obj":"Gene"},{"id":"100","span":{"begin":215,"end":218},"obj":"Gene"},{"id":"101","span":{"begin":341,"end":344},"obj":"Gene"},{"id":"102","span":{"begin":522,"end":527},"obj":"Gene"},{"id":"103","span":{"begin":529,"end":533},"obj":"Gene"},{"id":"104","span":{"begin":538,"end":543},"obj":"Gene"},{"id":"105","span":{"begin":418,"end":423},"obj":"Species"}],"attributes":[{"id":"A98","pred":"tao:has_database_id","subj":"98","obj":"Gene:923"},{"id":"A99","pred":"tao:has_database_id","subj":"99","obj":"Gene:923"},{"id":"A100","pred":"tao:has_database_id","subj":"100","obj":"Gene:923"},{"id":"A101","pred":"tao:has_database_id","subj":"101","obj":"Gene:923"},{"id":"A102","pred":"tao:has_database_id","subj":"102","obj":"Gene:7124"},{"id":"A103","pred":"tao:has_database_id","subj":"103","obj":"Gene:3569"},{"id":"A104","pred":"tao:has_database_id","subj":"104","obj":"Gene:3458"},{"id":"A105","pred":"tao:has_database_id","subj":"105","obj":"Tax:9606"},{"subj":"98","pred":"source","obj":"LitCovid-PubTator"},{"subj":"99","pred":"source","obj":"LitCovid-PubTator"},{"subj":"100","pred":"source","obj":"LitCovid-PubTator"},{"subj":"101","pred":"source","obj":"LitCovid-PubTator"},{"subj":"102","pred":"source","obj":"LitCovid-PubTator"},{"subj":"103","pred":"source","obj":"LitCovid-PubTator"},{"subj":"104","pred":"source","obj":"LitCovid-PubTator"},{"subj":"105","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T23","span":{"begin":0,"end":80},"obj":"Sentence"},{"id":"T24","span":{"begin":81,"end":201},"obj":"Sentence"},{"id":"T25","span":{"begin":202,"end":340},"obj":"Sentence"},{"id":"T26","span":{"begin":341,"end":548},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T23","pred":"source","obj":"LitCovid-sentences"},{"subj":"T24","pred":"source","obj":"LitCovid-sentences"},{"subj":"T25","pred":"source","obj":"LitCovid-sentences"},{"subj":"T26","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#c193ec","default":true},{"id":"LitCovid-sentences","color":"#93eca7"}]}]}}