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PMC:7781431 / 7633-8706 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
233 141-146 Gene denotes COX-2 Gene:5743
234 302-307 Gene denotes 5-LOX Gene:240
235 62-65 Chemical denotes EPA MESH:D015118
236 162-169 Chemical denotes aspirin MESH:D001241
237 211-217 Chemical denotes oxygen MESH:D010100
238 230-270 Chemical denotes 18R-hydro (peroxy)-eicosapentaenoic acid
239 272-280 Chemical denotes 18R-HEPE
240 319-327 Chemical denotes 18R-HEPE
241 331-352 Chemical denotes 5S (6)-epoxy-18R-HEPE
251 1001-1006 Gene denotes 5-LOX Gene:240
252 1011-1025 Gene denotes LTA4 hydrolase Gene:299732
253 466-471 Gene denotes 5-LOX Gene:240
254 878-881 Species denotes rat Tax:10116
255 445-453 Chemical denotes 18R HEPE
256 475-505 Chemical denotes 5S-hydroperoxy, 18-hydroxy-EPE
257 590-597 Chemical denotes 18-HEPE
258 1032-1040 Chemical denotes 18S-HEPE
259 768-780 Disease denotes inflammation MESH:D007249

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T53 0-18 Sentence denotes E-series resolvins
T54 19-66 Sentence denotes RvE is a di- or tri-hydroxyl metabolite of EPA.
T55 67-140 Sentence denotes To date, four RvEs (RvE1, 18S-RvE1, RvE2, and RvE3) have been discovered.
T56 141-282 Sentence denotes COX-2, acetylated by aspirin in hypoxic endothelial cells, introduces oxygen groups into 18R-hydro (peroxy)-eicosapentaenoic acid (18R-HEPE).
T57 283-404 Sentence denotes Activated PMN uses 5-LOX to convert 18R-HEPE to 5S (6)-epoxy-18R-HEPE, which is further hydrolyzed to RvE1 (Serhan et al.
T58 405-411 Sentence denotes 2000).
T59 412-531 Sentence denotes RvE2 is produced by reduction of 18R HEPE products by 5-LOX to 5S-hydroperoxy, 18-hydroxy-EPE in whole blood (Oh et al.
T60 532-538 Sentence denotes 2012).
T61 539-652 Sentence denotes Unlike RvE1, RvE2 and RvE3 are biosynthesized from 18-HEPE via the 12/15-LOX pathway in eosinophils (Isobe et al.
T62 653-660 Sentence denotes 2012b).
T63 661-793 Sentence denotes Endogenous RvE1 has been shown to accumulate for between 48 and 72 hours, which is a delayed time point of inflammation (Hong et al.
T64 794-800 Sentence denotes 2008).
T65 801-968 Sentence denotes RvE2 appeared at the time point corresponding to initial PMN infiltration in rat peritoneal exudate stimulated by zymosan A and decreased within 24 hours (Isobe et al.
T66 969-976 Sentence denotes 2012a).
T67 977-1066 Sentence denotes 18S-RvE1 is produced by 5-LOX and LTA4 hydrolase using 18S-HEPE as a substrate (Oh et al.
T68 1067-1073 Sentence denotes 2011).