> top > docs > PMC:7781431 > spans > 28687-30045 > annotations

PMC:7781431 / 28687-30045 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
816 21-42 Gene denotes Herpesviruses 1 and 2
817 44-49 Species denotes HSV-1 Tax:10298
818 54-59 Species denotes HSV-2 Tax:10310
819 87-111 Species denotes human alphaherpesvirus 1 Tax:10298
820 116-140 Species denotes human alphaherpesvirus 2 Tax:10310
821 172-177 Species denotes human Tax:9606
822 220-225 Species denotes human Tax:9606
823 178-194 Disease denotes viral infections MESH:D001102
824 248-263 Disease denotes Chayavichitsilp
825 312-321 Disease denotes infection MESH:D007239
826 466-478 Disease denotes inflammation MESH:D007249
827 515-524 Disease denotes blindness MESH:D001766
828 545-554 Disease denotes keratitis MESH:D007634
829 584-599 Disease denotes viral infection MESH:D001102
839 692-695 Gene denotes CD4 Gene:920
840 811-815 Gene denotes IFNγ Gene:3458
841 820-824 Gene denotes IL-6 Gene:3569
842 881-886 Gene denotes IL-10 Gene:3586
843 1202-1206 Species denotes mice Tax:10090
844 964-973 Disease denotes keratitis MESH:D007634
845 1114-1121 Disease denotes corneal MESH:D003316
846 1163-1180 Disease denotes keratitis lesions MESH:D007634
847 1243-1251 Disease denotes infected MESH:D007239

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T21 515-524 Phenotype denotes blindness http://purl.obolibrary.org/obo/HP_0000618
T22 545-554 Phenotype denotes keratitis http://purl.obolibrary.org/obo/HP_0000491
T23 964-973 Phenotype denotes keratitis http://purl.obolibrary.org/obo/HP_0000491
T24 1163-1172 Phenotype denotes keratitis http://purl.obolibrary.org/obo/HP_0000491

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T288 0-20 Sentence denotes Herpes simplex virus
T289 21-270 Sentence denotes Herpesviruses 1 and 2 (HSV-1 and HSV-2), with the taxonomic names human alphaherpesvirus 1 and human alphaherpesvirus 2, are the most common causes of human viral infections among the members of the human Herpesviridae family (Chayavichitsilp et al.
T290 271-277 Sentence denotes 2009).
T291 278-617 Sentence denotes Herpes simplex virus (HSV) ocular infection represents another example in which local control of the virus stems from a robust inflammatory response with long-term consequences of chronic inflammation, including the possibility of final blindness due to interstitial keratitis that persists even after the viral infection has been cleared.
T292 618-912 Sentence denotes In animals with HSV, topical administration of RvE1 reduced the influx of CD4+ T cells (both TH1 cells and TH17 cells) and neutrophils, decreased production of inflammatory cytokines including IFNγ and IL-6, and increased levels of the anti-inflammatory cytokine IL-10 (Fig. 4) (Rajasagi et al.
T293 913-919 Sentence denotes 2011).
T294 920-974 Sentence denotes Overall, RvE1 significantly reduced stromal keratitis.
T295 975-1043 Sentence denotes Similar results were demonstrated with PD1 (Fig. 4) (Rajasagi et al.
T296 1044-1050 Sentence denotes 2013).
T297 1051-1351 Sentence denotes Besides, AT-RvD1 treatment significantly reduced the degree of corneal angiogenesis and the severity of stromal keratitis lesions, and AT-RvD1 treated mice had fewer Th1 and Th17 cells in the infected cornea, as well as the reduced number of inflammatory cells, including neutrophils (Rajasagi et al.
T298 1352-1358 Sentence denotes 2017).