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PMC:7781431 / 26296-27260 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
747 66-76 Gene denotes annexin A1 Gene:301
748 78-83 Gene denotes ANXA1 Gene:301
749 261-266 Gene denotes ANXA1 Gene:301
750 276-280 Gene denotes FPR2 Gene:2358
751 309-313 Gene denotes ERK2 Gene:5594
752 399-403 Gene denotes FPR2 Gene:2358
753 697-700 Gene denotes SAA Gene:6287
754 816-820 Gene denotes FPR2 Gene:2358
755 821-824 Gene denotes ALX Gene:84941
756 864-868 Gene denotes FPR2 Gene:2358
757 869-872 Gene denotes ALX Gene:84941
758 100-109 Species denotes influenza Tax:11320
759 240-251 Chemical denotes sialic acid MESH:D019158
760 118-126 Disease denotes toxicity MESH:D064420
761 523-538 Disease denotes viral infection MESH:D001102
762 623-635 Disease denotes inflammation MESH:D007249
763 650-665 Disease denotes viral infection MESH:D001102
764 737-741 Disease denotes COPD MESH:D029424
765 766-788 Disease denotes virus coinfection acts MESH:D060085

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T18 737-741 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T262 0-144 Sentence denotes Annexin is the most abundant host cell protein in the virion, and annexin A1 (ANXA1) contributes to influenza-induced toxicity (Tcherniuk et al.
T263 145-151 Sentence denotes 2016).
T264 152-363 Sentence denotes That is, during virus entry into the host cell, viral hemagglutinin (HA) not only binds sialic acid but also ANXA1 binds to FPR2, resulting in activation of ERK2 and increased viral replication (Tcherniuk et al.
T265 364-370 Sentence denotes 2016).
T266 371-404 Sentence denotes RvD1 and LXA4 also activate FPR2.
T267 405-577 Sentence denotes It is still unknown whether RvD1 and LXA4 compete with viral annexin at the receptors site leads to the prevention of viral infection or the promotion of viral replication.
T268 578-679 Sentence denotes However, it is reported that AT-RvD1 reduces inflammation caused by the viral infection. (Wang et al.
T269 680-686 Sentence denotes 2017).
T270 687-957 Sentence denotes Increased SAA in recurrent acute exacerbations of COPD caused by bacterial and virus coinfection acts as a functional agonist of FPR2/ALX, antagonizing the protective action of FPR2/ALX by AT-RvD1, promoting chemotaxis of neutrophils and prolonging survival (Wang et al.
T271 958-964 Sentence denotes 2018).