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PMC:7781431 / 15867-16584 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
439 11-15 Gene denotes FPR2 Gene:2358
440 139-143 Gene denotes fMLP Gene:2357
441 196-200 Gene denotes FPR2 Gene:2358
442 201-204 Gene denotes ALX Gene:84941
443 252-256 Gene denotes FPR2 Gene:2358
444 257-260 Gene denotes ALX Gene:84941
445 111-137 Chemical denotes N-formyl methionyl peptide
446 348-350 Chemical denotes 3H MESH:D014316
447 439-443 Chemical denotes LXA4 MESH:C040527
448 572-578 Chemical denotes Serhan
449 525-538 Disease denotes efferocytosis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T152 0-155 Sentence denotes Originally FPR2 was classified as an FPR receptor due to its activation by the low-affinity endogenous agonist N-formyl methionyl peptide (fMLP) (Ye et al.
T153 156-162 Sentence denotes 1992).
T154 163-401 Sentence denotes The receptor was reclassified as FPR2/ALX, as LXA4 exhibited the highest affinity of all FPR2/ALX endogenous agonists through screening of various receptor ligands using radiolabelled [3H]-LXA4 and subsequent GTPase activity (Fiore et al.
T155 402-420 Sentence denotes 1994; Brink et al.
T156 421-427 Sentence denotes 2003).
T157 428-554 Sentence denotes Binding of LXA4 leads to the stimulation of monocyte chemotaxis, macrophage differentiation, and efferocytosis (Maderna et al.
T158 555-585 Sentence denotes 2010; Maddox and Serhan 1996).
T159 586-710 Sentence denotes LXA4 also reduces the adaptive immune response by reducing memory B cell antibody production and proliferation (Ramon et al.
T160 711-717 Sentence denotes 2014).