PMC:7755033 / 30404-34121 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7755033","sourcedb":"PMC","sourceid":"7755033","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7755033","text":"3.1. Virtual screening of prospective antiviral candidates from WS phytoconstituents on the basis of physicochemical parameters and Lipinski’s rule of five (PASS analysis)\nIn the drug discovery context, it is generally believed that an orally active drug candidate cannot have more than one violation of Lipinski’s criteria otherwise it might compromise its bioavailability (Balakrishnan et al., 2014).\nBased on Lipinski's rule of five, WS phytoconstituents were previously screened and selected for their drug like properties (Table 2). As is evident from Table 2, none of the selected WS phytoconstituents exhibited Lipinski’s violation. Interestingly, standard reference drugs cinacalcet and poziotinib displayed 1 violation each of Lipinski’s rule of five.\nTable 2. PASS analysis of WS phytoconstituents versus FDA-approved standard reference drugs (Losartan, Procainamide, Cinacalcet, Arbidol, Hydroxychloroquine, Oberadilol, Poziotinib).\nPhysicochemical properties\nS. No. Ligands Lipinski’s rule of 5 parameters\n% Absorption(\u003e50%)a Topological polar surface area (Å)2(TPSA)b(\u003c160 Å) MW (\u003c500) clog Pc(\u003c5) Hydrogen bond donors(NOHNH)(≤5) Hydrogen bond acceptors(NON)≤10) Number of rotatable bonds(≤10) Lipinski’s violation (LV)\n1. Withaferin A 75.76 96.36 470.61 2.49 2 6 3 0\n2. Withanolide A 75.76 96.36 470.61 2.56 2 6 2 0\n3. Withanolide B 82.74 76.13 454.61 3.42 1 5 2 0\n4. Withanolide D 75.76 96.36 470.61 2.56 2 6 2 0\n5. Withanolide E 68.78 116.59 486.61 1.77 3 7 2 0\n6. Withanone 75.76 96.36 470.61 2.60 2 6 2 0\n7. Viscosalactone B 68.78 116.59 488.62 1.92 3 7 3 0\n8. Anaferine 94.81 41.12 224.35 1.47 2 3 4 0\n9. Withasomnine 102.85 17.83 184.24 2.65 0 2 1 0\n10. Losartan 77.09 92.5 422.9 3.95 2 5 8 0\n11. Procainamide 88.85 58.4 235.33 0.93 2 3 6 0\n12. Cinacalcet 104.86 12 357.4 5.65 1 4 6 1\n13. Arbidol 81.4 80 477.4 4.17 1 5 8 0\n14. Hydroxychloroquine 92.31 48.38 335.88 3.08 2 4 9 0\n15. Oberadilol 67.95 119 484 2.80 4 7 10 0\n16. Poziotinib 82.57 76.6 491.3 5.29 1 7 6 1\nRule: aPercentage absorption was calculated as: % absorption = 109 – [0.345 × topological polar surface area].\nbTopological polar surface area (defined as a sum of surfaces of polar atoms in a molecule).\ncLogarithm of compound partition coefficient between n-octanol and water. WS phytoconstituents were further analyzed using additional filters viz. Ghose, Veber, Egan, Muegge and Leadlikeness filters (Table 3). The selected phytoconstituents showed no violations of Veber, Egan and Muegge filters thereby indicating their drug-like character. The drug cinacalcet showed 1 and 2 violations of Egan and Muegge filters, respectively, whereas drug poziotinib exhibited 1 violation of Muegge filter.\nTable 3. Drug-like character of WS phytoconstituents versus FDA-approved standard reference drugs (Losartan, Procainamide, Cinacalcet, Arbidol, Hydroxychloroquine, Oberadilol, Poziotinib).\nS. No. Ligands GNo. of vio.a VNo. of vio.b ENo. of vio.c MNo. ofvio.d Leadlikeness\n1. Withaferin A 1 0 0 0 2\n2. Withanolide A 1 0 0 0 1\n3. Withanolide B 1 0 0 0 2\n4. Withanolide D 1 0 0 0 1\n5. Withanolide E 2 0 0 0 1\n6. Withanone 1 0 0 0 1\n7. Viscosalactone B 1 0 0 0 1\n8. Anaferine 0 0 0 0 1\n9. Withasomnine 0 0 0 0 1\n10. Losartan 0 0 0 0 3\n11. Procainamide 0 0 0 0 1\n12. Cinacalcet 1 0 1 2 2\n13. Arbidol 0 0 0 0 3\n14. Hydroxychloroquine 0 0 0 0 2\n15. Oberadilol 2 0 0 0 2\n16. Poziotinib 2 0 0 1 2\nRule: aGhose filter.\nbVeber filter.\ncEgan (Pharmacial) filter.\ndMuegge (Bayer) filter.","divisions":[{"label":"label","span":{"begin":0,"end":4}},{"label":"title","span":{"begin":6,"end":172}},{"label":"p","span":{"begin":173,"end":403}},{"label":"p","span":{"begin":404,"end":761}},{"label":"table-wrap","span":{"begin":762,"end":2419}},{"label":"label","span":{"begin":762,"end":770}},{"label":"caption","span":{"begin":772,"end":945}},{"label":"p","span":{"begin":772,"end":945}},{"label":"table","span":{"begin":946,"end":2141}},{"label":"tr","span":{"begin":946,"end":972}},{"label":"th","span":{"begin":946,"end":972}},{"label":"tr","span":{"begin":973,"end":1021}},{"label":"th","span":{"begin":973,"end":979}},{"label":"th","span":{"begin":981,"end":988}},{"label":"th","span":{"begin":990,"end":1021}},{"label":"tr","span":{"begin":1022,"end":1243}},{"label":"th","span":{"begin":1022,"end":1041}},{"label":"th","span":{"begin":1043,"end":1093}},{"label":"th","span":{"begin":1095,"end":1104}},{"label":"th","span":{"begin":1106,"end":1117}},{"label":"th","span":{"begin":1119,"end":1150}},{"label":"th","span":{"begin":1152,"end":1184}},{"label":"th","span":{"begin":1186,"end":1216}},{"label":"th","span":{"begin":1218,"end":1243}},{"label":"tr","span":{"begin":1244,"end":1300}},{"label":"td","span":{"begin":1244,"end":1246}},{"label":"td","span":{"begin":1248,"end":1260}},{"label":"td","span":{"begin":1262,"end":1267}},{"label":"td","span":{"begin":1269,"end":1274}},{"label":"td","span":{"begin":1276,"end":1282}},{"label":"td","span":{"begin":1284,"end":1288}},{"label":"td","span":{"begin":1290,"end":1291}},{"label":"td","span":{"begin":1293,"end":1294}},{"label":"td","span":{"begin":1296,"end":1297}},{"label":"td","span":{"begin":1299,"end":1300}},{"label":"tr","span":{"begin":1301,"end":1358}},{"label":"td","span":{"begin":1301,"end":1303}},{"label":"td","span":{"begin":1305,"end":1318}},{"label":"td","span":{"begin":1320,"end":1325}},{"label":"td","span":{"begin":1327,"end":1332}},{"label":"td","span":{"begin":1334,"end":1340}},{"label":"td","span":{"begin":1342,"end":1346}},{"label":"td","span":{"begin":1348,"end":1349}},{"label":"td","span":{"begin":1351,"end":1352}},{"label":"td","span":{"begin":1354,"end":1355}},{"label":"td","span":{"begin":1357,"end":1358}},{"label":"tr","span":{"begin":1359,"end":1416}},{"label":"td","span":{"begin":1359,"end":1361}},{"label":"td","span":{"begin":1363,"end":1376}},{"label":"td","span":{"begin":1378,"end":1383}},{"label":"td","span":{"begin":1385,"end":1390}},{"label":"td","span":{"begin":1392,"end":1398}},{"label":"td","span":{"begin":1400,"end":1404}},{"label":"td","span":{"begin":1406,"end":1407}},{"label":"td","span":{"begin":1409,"end":1410}},{"label":"td","span":{"begin":1412,"end":1413}},{"label":"td","span":{"begin":1415,"end":1416}},{"label":"tr","span":{"begin":1417,"end":1474}},{"label":"td","span":{"begin":1417,"end":1419}},{"label":"td","span":{"begin":1421,"end":1434}},{"label":"td","span":{"begin":1436,"end":1441}},{"label":"td","span":{"begin":1443,"end":1448}},{"label":"td","span":{"begin":1450,"end":1456}},{"label":"td","span":{"begin":1458,"end":1462}},{"label":"td","span":{"begin":1464,"end":1465}},{"label":"td","span":{"begin":1467,"end":1468}},{"label":"td","span":{"begin":1470,"end":1471}},{"label":"td","span":{"begin":1473,"end":1474}},{"label":"tr","span":{"begin":1475,"end":1533}},{"label":"td","span":{"begin":1475,"end":1477}},{"label":"td","span":{"begin":1479,"end":1492}},{"label":"td","span":{"begin":1494,"end":1499}},{"label":"td","span":{"begin":1501,"end":1507}},{"label":"td","span":{"begin":1509,"end":1515}},{"label":"td","span":{"begin":1517,"end":1521}},{"label":"td","span":{"begin":1523,"end":1524}},{"label":"td","span":{"begin":1526,"end":1527}},{"label":"td","span":{"begin":1529,"end":1530}},{"label":"td","span":{"begin":1532,"end":1533}},{"label":"tr","span":{"begin":1534,"end":1587}},{"label":"td","span":{"begin":1534,"end":1536}},{"label":"td","span":{"begin":1538,"end":1547}},{"label":"td","span":{"begin":1549,"end":1554}},{"label":"td","span":{"begin":1556,"end":1561}},{"label":"td","span":{"begin":1563,"end":1569}},{"label":"td","span":{"begin":1571,"end":1575}},{"label":"td","span":{"begin":1577,"end":1578}},{"label":"td","span":{"begin":1580,"end":1581}},{"label":"td","span":{"begin":1583,"end":1584}},{"label":"td","span":{"begin":1586,"end":1587}},{"label":"tr","span":{"begin":1588,"end":1649}},{"label":"td","span":{"begin":1588,"end":1590}},{"label":"td","span":{"begin":1592,"end":1608}},{"label":"td","span":{"begin":1610,"end":1615}},{"label":"td","span":{"begin":1617,"end":1623}},{"label":"td","span":{"begin":1625,"end":1631}},{"label":"td","span":{"begin":1633,"end":1637}},{"label":"td","span":{"begin":1639,"end":1640}},{"label":"td","span":{"begin":1642,"end":1643}},{"label":"td","span":{"begin":1645,"end":1646}},{"label":"td","span":{"begin":1648,"end":1649}},{"label":"tr","span":{"begin":1650,"end":1703}},{"label":"td","span":{"begin":1650,"end":1652}},{"label":"td","span":{"begin":1654,"end":1663}},{"label":"td","span":{"begin":1665,"end":1670}},{"label":"td","span":{"begin":1672,"end":1677}},{"label":"td","span":{"begin":1679,"end":1685}},{"label":"td","span":{"begin":1687,"end":1691}},{"label":"td","span":{"begin":1693,"end":1694}},{"label":"td","span":{"begin":1696,"end":1697}},{"label":"td","span":{"begin":1699,"end":1700}},{"label":"td","span":{"begin":1702,"end":1703}},{"label":"tr","span":{"begin":1704,"end":1761}},{"label":"td","span":{"begin":1704,"end":1706}},{"label":"td","span":{"begin":1708,"end":1720}},{"label":"td","span":{"begin":1722,"end":1728}},{"label":"td","span":{"begin":1730,"end":1735}},{"label":"td","span":{"begin":1737,"end":1743}},{"label":"td","span":{"begin":1745,"end":1749}},{"label":"td","span":{"begin":1751,"end":1752}},{"label":"td","span":{"begin":1754,"end":1755}},{"label":"td","span":{"begin":1757,"end":1758}},{"label":"td","span":{"begin":1760,"end":1761}},{"label":"tr","span":{"begin":1762,"end":1813}},{"label":"td","span":{"begin":1762,"end":1765}},{"label":"td","span":{"begin":1767,"end":1775}},{"label":"td","span":{"begin":1777,"end":1782}},{"label":"td","span":{"begin":1784,"end":1788}},{"label":"td","span":{"begin":1790,"end":1795}},{"label":"td","span":{"begin":1797,"end":1801}},{"label":"td","span":{"begin":1803,"end":1804}},{"label":"td","span":{"begin":1806,"end":1807}},{"label":"td","span":{"begin":1809,"end":1810}},{"label":"td","span":{"begin":1812,"end":1813}},{"label":"tr","span":{"begin":1814,"end":1870}},{"label":"td","span":{"begin":1814,"end":1817}},{"label":"td","span":{"begin":1819,"end":1831}},{"label":"td","span":{"begin":1833,"end":1838}},{"label":"td","span":{"begin":1840,"end":1844}},{"label":"td","span":{"begin":1846,"end":1852}},{"label":"td","span":{"begin":1854,"end":1858}},{"label":"td","span":{"begin":1860,"end":1861}},{"label":"td","span":{"begin":1863,"end":1864}},{"label":"td","span":{"begin":1866,"end":1867}},{"label":"td","span":{"begin":1869,"end":1870}},{"label":"tr","span":{"begin":1871,"end":1923}},{"label":"td","span":{"begin":1871,"end":1874}},{"label":"td","span":{"begin":1876,"end":1886}},{"label":"td","span":{"begin":1888,"end":1894}},{"label":"td","span":{"begin":1896,"end":1898}},{"label":"td","span":{"begin":1900,"end":1905}},{"label":"td","span":{"begin":1907,"end":1911}},{"label":"td","span":{"begin":1913,"end":1914}},{"label":"td","span":{"begin":1916,"end":1917}},{"label":"td","span":{"begin":1919,"end":1920}},{"label":"td","span":{"begin":1922,"end":1923}},{"label":"tr","span":{"begin":1924,"end":1971}},{"label":"td","span":{"begin":1924,"end":1927}},{"label":"td","span":{"begin":1929,"end":1936}},{"label":"td","span":{"begin":1938,"end":1942}},{"label":"td","span":{"begin":1944,"end":1946}},{"label":"td","span":{"begin":1948,"end":1953}},{"label":"td","span":{"begin":1955,"end":1959}},{"label":"td","span":{"begin":1961,"end":1962}},{"label":"td","span":{"begin":1964,"end":1965}},{"label":"td","span":{"begin":1967,"end":1968}},{"label":"td","span":{"begin":1970,"end":1971}},{"label":"tr","span":{"begin":1972,"end":2035}},{"label":"td","span":{"begin":1972,"end":1975}},{"label":"td","span":{"begin":1977,"end":1995}},{"label":"td","span":{"begin":1997,"end":2002}},{"label":"td","span":{"begin":2004,"end":2009}},{"label":"td","span":{"begin":2011,"end":2017}},{"label":"td","span":{"begin":2019,"end":2023}},{"label":"td","span":{"begin":2025,"end":2026}},{"label":"td","span":{"begin":2028,"end":2029}},{"label":"td","span":{"begin":2031,"end":2032}},{"label":"td","span":{"begin":2034,"end":2035}},{"label":"tr","span":{"begin":2036,"end":2087}},{"label":"td","span":{"begin":2036,"end":2039}},{"label":"td","span":{"begin":2041,"end":2051}},{"label":"td","span":{"begin":2053,"end":2058}},{"label":"td","span":{"begin":2060,"end":2063}},{"label":"td","span":{"begin":2065,"end":2068}},{"label":"td","span":{"begin":2070,"end":2074}},{"label":"td","span":{"begin":2076,"end":2077}},{"label":"td","span":{"begin":2079,"end":2080}},{"label":"td","span":{"begin":2082,"end":2084}},{"label":"td","span":{"begin":2086,"end":2087}},{"label":"tr","span":{"begin":2088,"end":2141}},{"label":"td","span":{"begin":2088,"end":2091}},{"label":"td","span":{"begin":2093,"end":2103}},{"label":"td","span":{"begin":2105,"end":2110}},{"label":"td","span":{"begin":2112,"end":2116}},{"label":"td","span":{"begin":2118,"end":2123}},{"label":"td","span":{"begin":2125,"end":2129}},{"label":"td","span":{"begin":2131,"end":2132}},{"label":"td","span":{"begin":2134,"end":2135}},{"label":"td","span":{"begin":2137,"end":2138}},{"label":"td","span":{"begin":2140,"end":2141}},{"label":"table-wrap-foot","span":{"begin":2142,"end":2419}},{"label":"footnote","span":{"begin":2142,"end":2252}},{"label":"p","span":{"begin":2142,"end":2252}},{"label":"footnote","span":{"begin":2253,"end":2345}},{"label":"p","span":{"begin":2253,"end":2345}},{"label":"footnote","span":{"begin":2346,"end":2419}},{"label":"p","span":{"begin":2346,"end":2419}},{"label":"p","span":{"begin":2420,"end":2839}},{"label":"label","span":{"begin":2840,"end":2848}},{"label":"caption","span":{"begin":2850,"end":3029}},{"label":"p","span":{"begin":2850,"end":3029}},{"label":"table","span":{"begin":3030,"end":3630}},{"label":"tr","span":{"begin":3030,"end":3118}},{"label":"th","span":{"begin":3030,"end":3036}},{"label":"th","span":{"begin":3038,"end":3045}},{"label":"th","span":{"begin":3047,"end":3060}},{"label":"th","span":{"begin":3062,"end":3075}},{"label":"th","span":{"begin":3077,"end":3090}},{"label":"th","span":{"begin":3092,"end":3104}},{"label":"th","span":{"begin":3106,"end":3118}},{"label":"tr","span":{"begin":3119,"end":3150}},{"label":"td","span":{"begin":3119,"end":3121}},{"label":"td","span":{"begin":3123,"end":3135}},{"label":"td","span":{"begin":3137,"end":3138}},{"label":"td","span":{"begin":3140,"end":3141}},{"label":"td","span":{"begin":3143,"end":3144}},{"label":"td","span":{"begin":3146,"end":3147}},{"label":"td","span":{"begin":3149,"end":3150}},{"label":"tr","span":{"begin":3151,"end":3183}},{"label":"td","span":{"begin":3151,"end":3153}},{"label":"td","span":{"begin":3155,"end":3168}},{"label":"td","span":{"begin":3170,"end":3171}},{"label":"td","span":{"begin":3173,"end":3174}},{"label":"td","span":{"begin":3176,"end":3177}},{"label":"td","span":{"begin":3179,"end":3180}},{"label":"td","span":{"begin":3182,"end":3183}},{"label":"tr","span":{"begin":3184,"end":3216}},{"label":"td","span":{"begin":3184,"end":3186}},{"label":"td","span":{"begin":3188,"end":3201}},{"label":"td","span":{"begin":3203,"end":3204}},{"label":"td","span":{"begin":3206,"end":3207}},{"label":"td","span":{"begin":3209,"end":3210}},{"label":"td","span":{"begin":3212,"end":3213}},{"label":"td","span":{"begin":3215,"end":3216}},{"label":"tr","span":{"begin":3217,"end":3249}},{"label":"td","span":{"begin":3217,"end":3219}},{"label":"td","span":{"begin":3221,"end":3234}},{"label":"td","span":{"begin":3236,"end":3237}},{"label":"td","span":{"begin":3239,"end":3240}},{"label":"td","span":{"begin":3242,"end":3243}},{"label":"td","span":{"begin":3245,"end":3246}},{"label":"td","span":{"begin":3248,"end":3249}},{"label":"tr","span":{"begin":3250,"end":3282}},{"label":"td","span":{"begin":3250,"end":3252}},{"label":"td","span":{"begin":3254,"end":3267}},{"label":"td","span":{"begin":3269,"end":3270}},{"label":"td","span":{"begin":3272,"end":3273}},{"label":"td","span":{"begin":3275,"end":3276}},{"label":"td","span":{"begin":3278,"end":3279}},{"label":"td","span":{"begin":3281,"end":3282}},{"label":"tr","span":{"begin":3283,"end":3311}},{"label":"td","span":{"begin":3283,"end":3285}},{"label":"td","span":{"begin":3287,"end":3296}},{"label":"td","span":{"begin":3298,"end":3299}},{"label":"td","span":{"begin":3301,"end":3302}},{"label":"td","span":{"begin":3304,"end":3305}},{"label":"td","span":{"begin":3307,"end":3308}},{"label":"td","span":{"begin":3310,"end":3311}},{"label":"tr","span":{"begin":3312,"end":3347}},{"label":"td","span":{"begin":3312,"end":3314}},{"label":"td","span":{"begin":3316,"end":3332}},{"label":"td","span":{"begin":3334,"end":3335}},{"label":"td","span":{"begin":3337,"end":3338}},{"label":"td","span":{"begin":3340,"end":3341}},{"label":"td","span":{"begin":3343,"end":3344}},{"label":"td","span":{"begin":3346,"end":3347}},{"label":"tr","span":{"begin":3348,"end":3376}},{"label":"td","span":{"begin":3348,"end":3350}},{"label":"td","span":{"begin":3352,"end":3361}},{"label":"td","span":{"begin":3363,"end":3364}},{"label":"td","span":{"begin":3366,"end":3367}},{"label":"td","span":{"begin":3369,"end":3370}},{"label":"td","span":{"begin":3372,"end":3373}},{"label":"td","span":{"begin":3375,"end":3376}},{"label":"tr","span":{"begin":3377,"end":3408}},{"label":"td","span":{"begin":3377,"end":3379}},{"label":"td","span":{"begin":3381,"end":3393}},{"label":"td","span":{"begin":3395,"end":3396}},{"label":"td","span":{"begin":3398,"end":3399}},{"label":"td","span":{"begin":3401,"end":3402}},{"label":"td","span":{"begin":3404,"end":3405}},{"label":"td","span":{"begin":3407,"end":3408}},{"label":"tr","span":{"begin":3409,"end":3437}},{"label":"td","span":{"begin":3409,"end":3412}},{"label":"td","span":{"begin":3414,"end":3422}},{"label":"td","span":{"begin":3424,"end":3425}},{"label":"td","span":{"begin":3427,"end":3428}},{"label":"td","span":{"begin":3430,"end":3431}},{"label":"td","span":{"begin":3433,"end":3434}},{"label":"td","span":{"begin":3436,"end":3437}},{"label":"tr","span":{"begin":3438,"end":3470}},{"label":"td","span":{"begin":3438,"end":3441}},{"label":"td","span":{"begin":3443,"end":3455}},{"label":"td","span":{"begin":3457,"end":3458}},{"label":"td","span":{"begin":3460,"end":3461}},{"label":"td","span":{"begin":3463,"end":3464}},{"label":"td","span":{"begin":3466,"end":3467}},{"label":"td","span":{"begin":3469,"end":3470}},{"label":"tr","span":{"begin":3471,"end":3501}},{"label":"td","span":{"begin":3471,"end":3474}},{"label":"td","span":{"begin":3476,"end":3486}},{"label":"td","span":{"begin":3488,"end":3489}},{"label":"td","span":{"begin":3491,"end":3492}},{"label":"td","span":{"begin":3494,"end":3495}},{"label":"td","span":{"begin":3497,"end":3498}},{"label":"td","span":{"begin":3500,"end":3501}},{"label":"tr","span":{"begin":3502,"end":3529}},{"label":"td","span":{"begin":3502,"end":3505}},{"label":"td","span":{"begin":3507,"end":3514}},{"label":"td","span":{"begin":3516,"end":3517}},{"label":"td","span":{"begin":3519,"end":3520}},{"label":"td","span":{"begin":3522,"end":3523}},{"label":"td","span":{"begin":3525,"end":3526}},{"label":"td","span":{"begin":3528,"end":3529}},{"label":"tr","span":{"begin":3530,"end":3568}},{"label":"td","span":{"begin":3530,"end":3533}},{"label":"td","span":{"begin":3535,"end":3553}},{"label":"td","span":{"begin":3555,"end":3556}},{"label":"td","span":{"begin":3558,"end":3559}},{"label":"td","span":{"begin":3561,"end":3562}},{"label":"td","span":{"begin":3564,"end":3565}},{"label":"td","span":{"begin":3567,"end":3568}},{"label":"tr","span":{"begin":3569,"end":3599}},{"label":"td","span":{"begin":3569,"end":3572}},{"label":"td","span":{"begin":3574,"end":3584}},{"label":"td","span":{"begin":3586,"end":3587}},{"label":"td","span":{"begin":3589,"end":3590}},{"label":"td","span":{"begin":3592,"end":3593}},{"label":"td","span":{"begin":3595,"end":3596}},{"label":"td","span":{"begin":3598,"end":3599}},{"label":"tr","span":{"begin":3600,"end":3630}},{"label":"td","span":{"begin":3600,"end":3603}},{"label":"td","span":{"begin":3605,"end":3615}},{"label":"td","span":{"begin":3617,"end":3618}},{"label":"td","span":{"begin":3620,"end":3621}},{"label":"td","span":{"begin":3623,"end":3624}},{"label":"td","span":{"begin":3626,"end":3627}},{"label":"td","span":{"begin":3629,"end":3630}},{"label":"footnote","span":{"begin":3631,"end":3651}},{"label":"p","span":{"begin":3631,"end":3651}},{"label":"footnote","span":{"begin":3652,"end":3666}},{"label":"p","span":{"begin":3652,"end":3666}},{"label":"footnote","span":{"begin":3667,"end":3693}},{"label":"p","span":{"begin":3667,"end":3693}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"515","span":{"begin":65,"end":67},"obj":"Species"},{"id":"520","span":{"begin":438,"end":440},"obj":"Species"},{"id":"521","span":{"begin":588,"end":590},"obj":"Species"},{"id":"522","span":{"begin":681,"end":691},"obj":"Chemical"},{"id":"523","span":{"begin":696,"end":706},"obj":"Chemical"},{"id":"532","span":{"begin":789,"end":791},"obj":"Species"},{"id":"533","span":{"begin":856,"end":864},"obj":"Chemical"},{"id":"534","span":{"begin":866,"end":878},"obj":"Chemical"},{"id":"535","span":{"begin":880,"end":890},"obj":"Chemical"},{"id":"536","span":{"begin":892,"end":899},"obj":"Chemical"},{"id":"537","span":{"begin":901,"end":919},"obj":"Chemical"},{"id":"538","span":{"begin":921,"end":931},"obj":"Chemical"},{"id":"539","span":{"begin":933,"end":943},"obj":"Chemical"},{"id":"558","span":{"begin":1119,"end":1127},"obj":"Chemical"},{"id":"559","span":{"begin":1152,"end":1160},"obj":"Chemical"},{"id":"560","span":{"begin":1248,"end":1260},"obj":"Chemical"},{"id":"561","span":{"begin":1305,"end":1316},"obj":"Chemical"},{"id":"562","span":{"begin":1363,"end":1374},"obj":"Chemical"},{"id":"563","span":{"begin":1421,"end":1432},"obj":"Chemical"},{"id":"564","span":{"begin":1479,"end":1490},"obj":"Chemical"},{"id":"565","span":{"begin":1538,"end":1547},"obj":"Chemical"},{"id":"566","span":{"begin":1592,"end":1606},"obj":"Chemical"},{"id":"567","span":{"begin":1654,"end":1663},"obj":"Chemical"},{"id":"568","span":{"begin":1708,"end":1720},"obj":"Chemical"},{"id":"569","span":{"begin":1767,"end":1775},"obj":"Chemical"},{"id":"570","span":{"begin":1819,"end":1831},"obj":"Chemical"},{"id":"571","span":{"begin":1876,"end":1886},"obj":"Chemical"},{"id":"572","span":{"begin":1929,"end":1936},"obj":"Chemical"},{"id":"573","span":{"begin":1977,"end":1995},"obj":"Chemical"},{"id":"574","span":{"begin":2041,"end":2051},"obj":"Chemical"},{"id":"575","span":{"begin":2093,"end":2103},"obj":"Chemical"},{"id":"579","span":{"begin":2346,"end":2356},"obj":"Chemical"},{"id":"580","span":{"begin":2399,"end":2408},"obj":"Chemical"},{"id":"581","span":{"begin":2413,"end":2418},"obj":"Chemical"},{"id":"585","span":{"begin":2420,"end":2422},"obj":"Species"},{"id":"586","span":{"begin":2697,"end":2707},"obj":"Chemical"},{"id":"587","span":{"begin":2789,"end":2799},"obj":"Chemical"},{"id":"596","span":{"begin":2873,"end":2875},"obj":"Species"},{"id":"597","span":{"begin":2940,"end":2948},"obj":"Chemical"},{"id":"598","span":{"begin":2950,"end":2962},"obj":"Chemical"},{"id":"599","span":{"begin":2964,"end":2974},"obj":"Chemical"},{"id":"600","span":{"begin":2976,"end":2983},"obj":"Chemical"},{"id":"601","span":{"begin":2985,"end":3003},"obj":"Chemical"},{"id":"602","span":{"begin":3005,"end":3015},"obj":"Chemical"},{"id":"603","span":{"begin":3017,"end":3027},"obj":"Chemical"},{"id":"620","span":{"begin":3047,"end":3050},"obj":"Chemical"},{"id":"621","span":{"begin":3123,"end":3138},"obj":"Chemical"},{"id":"622","span":{"begin":3155,"end":3168},"obj":"Chemical"},{"id":"623","span":{"begin":3221,"end":3232},"obj":"Chemical"},{"id":"624","span":{"begin":3254,"end":3265},"obj":"Chemical"},{"id":"625","span":{"begin":3287,"end":3296},"obj":"Chemical"},{"id":"626","span":{"begin":3316,"end":3332},"obj":"Chemical"},{"id":"627","span":{"begin":3352,"end":3361},"obj":"Chemical"},{"id":"628","span":{"begin":3381,"end":3393},"obj":"Chemical"},{"id":"629","span":{"begin":3414,"end":3422},"obj":"Chemical"},{"id":"630","span":{"begin":3443,"end":3455},"obj":"Chemical"},{"id":"631","span":{"begin":3476,"end":3486},"obj":"Chemical"},{"id":"632","span":{"begin":3507,"end":3514},"obj":"Chemical"},{"id":"633","span":{"begin":3535,"end":3553},"obj":"Chemical"},{"id":"634","span":{"begin":3574,"end":3584},"obj":"Chemical"},{"id":"635","span":{"begin":3605,"end":3615},"obj":"Chemical"}],"attributes":[{"id":"A515","pred":"tao:has_database_id","subj":"515","obj":"Tax:126910"},{"id":"A520","pred":"tao:has_database_id","subj":"520","obj":"Tax:126910"},{"id":"A521","pred":"tao:has_database_id","subj":"521","obj":"Tax:126910"},{"id":"A522","pred":"tao:has_database_id","subj":"522","obj":"MESH:D000069449"},{"id":"A523","pred":"tao:has_database_id","subj":"523","obj":"MESH:C557213"},{"id":"A532","pred":"tao:has_database_id","subj":"532","obj":"Tax:126910"},{"id":"A534","pred":"tao:has_database_id","subj":"534","obj":"MESH:D011342"},{"id":"A535","pred":"tao:has_database_id","subj":"535","obj":"MESH:D000069449"},{"id":"A536","pred":"tao:has_database_id","subj":"536","obj":"MESH:C086979"},{"id":"A537","pred":"tao:has_database_id","subj":"537","obj":"MESH:D006886"},{"id":"A539","pred":"tao:has_database_id","subj":"539","obj":"MESH:C557213"},{"id":"A558","pred":"tao:has_database_id","subj":"558","obj":"MESH:D006859"},{"id":"A559","pred":"tao:has_database_id","subj":"559","obj":"MESH:D006859"},{"id":"A561","pred":"tao:has_database_id","subj":"561","obj":"MESH:D054358"},{"id":"A562","pred":"tao:has_database_id","subj":"562","obj":"MESH:D054358"},{"id":"A563","pred":"tao:has_database_id","subj":"563","obj":"MESH:D054358"},{"id":"A564","pred":"tao:has_database_id","subj":"564","obj":"MESH:D054358"},{"id":"A565","pred":"tao:has_database_id","subj":"565","obj":"MESH:C560597"},{"id":"A568","pred":"tao:has_database_id","subj":"568","obj":"MESH:C568582"},{"id":"A570","pred":"tao:has_database_id","subj":"570","obj":"MESH:D011342"},{"id":"A571","pred":"tao:has_database_id","subj":"571","obj":"MESH:D000069449"},{"id":"A572","pred":"tao:has_database_id","subj":"572","obj":"MESH:C086979"},{"id":"A573","pred":"tao:has_database_id","subj":"573","obj":"MESH:D006886"},{"id":"A575","pred":"tao:has_database_id","subj":"575","obj":"MESH:C557213"},{"id":"A580","pred":"tao:has_database_id","subj":"580","obj":"MESH:D020003"},{"id":"A581","pred":"tao:has_database_id","subj":"581","obj":"MESH:D014867"},{"id":"A585","pred":"tao:has_database_id","subj":"585","obj":"Tax:126910"},{"id":"A586","pred":"tao:has_database_id","subj":"586","obj":"MESH:D000069449"},{"id":"A587","pred":"tao:has_database_id","subj":"587","obj":"MESH:C557213"},{"id":"A596","pred":"tao:has_database_id","subj":"596","obj":"Tax:126910"},{"id":"A598","pred":"tao:has_database_id","subj":"598","obj":"MESH:D011342"},{"id":"A599","pred":"tao:has_database_id","subj":"599","obj":"MESH:D000069449"},{"id":"A600","pred":"tao:has_database_id","subj":"600","obj":"MESH:C086979"},{"id":"A601","pred":"tao:has_database_id","subj":"601","obj":"MESH:D006886"},{"id":"A603","pred":"tao:has_database_id","subj":"603","obj":"MESH:C557213"},{"id":"A623","pred":"tao:has_database_id","subj":"623","obj":"MESH:D054358"},{"id":"A624","pred":"tao:has_database_id","subj":"624","obj":"MESH:D054358"},{"id":"A625","pred":"tao:has_database_id","subj":"625","obj":"MESH:C560597"},{"id":"A628","pred":"tao:has_database_id","subj":"628","obj":"MESH:C568582"},{"id":"A630","pred":"tao:has_database_id","subj":"630","obj":"MESH:D011342"},{"id":"A631","pred":"tao:has_database_id","subj":"631","obj":"MESH:D000069449"},{"id":"A632","pred":"tao:has_database_id","subj":"632","obj":"MESH:C086979"},{"id":"A633","pred":"tao:has_database_id","subj":"633","obj":"MESH:D006886"},{"id":"A635","pred":"tao:has_database_id","subj":"635","obj":"MESH:C557213"},{"subj":"515","pred":"source","obj":"LitCovid-PubTator"},{"subj":"520","pred":"source","obj":"LitCovid-PubTator"},{"subj":"521","pred":"source","obj":"LitCovid-PubTator"},{"subj":"522","pred":"source","obj":"LitCovid-PubTator"},{"subj":"523","pred":"source","obj":"LitCovid-PubTator"},{"subj":"532","pred":"source","obj":"LitCovid-PubTator"},{"subj":"533","pred":"source","obj":"LitCovid-PubTator"},{"subj":"534","pred":"source","obj":"LitCovid-PubTator"},{"subj":"535","pred":"source","obj":"LitCovid-PubTator"},{"subj":"536","pred":"source","obj":"LitCovid-PubTator"},{"subj":"537","pred":"source","obj":"LitCovid-PubTator"},{"subj":"538","pred":"source","obj":"LitCovid-PubTator"},{"subj":"539","pred":"source","obj":"LitCovid-PubTator"},{"subj":"558","pred":"source","obj":"LitCovid-PubTator"},{"subj":"559","pred":"source","obj":"LitCovid-PubTator"},{"subj":"560","pred":"source","obj":"LitCovid-PubTator"},{"subj":"561","pred":"source","obj":"LitCovid-PubTator"},{"subj":"562","pred":"source","obj":"LitCovid-PubTator"},{"subj":"563","pred":"source","obj":"LitCovid-PubTator"},{"subj":"564","pred":"source","obj":"LitCovid-PubTator"},{"subj":"565","pred":"source","obj":"LitCovid-PubTator"},{"subj":"566","pred":"source","obj":"LitCovid-PubTator"},{"subj":"567","pred":"source","obj":"LitCovid-PubTator"},{"subj":"568","pred":"source","obj":"LitCovid-PubTator"},{"subj":"569","pred":"source","obj":"LitCovid-PubTator"},{"subj":"570","pred":"source","obj":"LitCovid-PubTator"},{"subj":"571","pred":"source","obj":"LitCovid-PubTator"},{"subj":"572","pred":"source","obj":"LitCovid-PubTator"},{"subj":"573","pred":"source","obj":"LitCovid-PubTator"},{"subj":"574","pred":"source","obj":"LitCovid-PubTator"},{"subj":"575","pred":"source","obj":"LitCovid-PubTator"},{"subj":"579","pred":"source","obj":"LitCovid-PubTator"},{"subj":"580","pred":"source","obj":"LitCovid-PubTator"},{"subj":"581","pred":"source","obj":"LitCovid-PubTator"},{"subj":"585","pred":"source","obj":"LitCovid-PubTator"},{"subj":"586","pred":"source","obj":"LitCovid-PubTator"},{"subj":"587","pred":"source","obj":"LitCovid-PubTator"},{"subj":"596","pred":"source","obj":"LitCovid-PubTator"},{"subj":"597","pred":"source","obj":"LitCovid-PubTator"},{"subj":"598","pred":"source","obj":"LitCovid-PubTator"},{"subj":"599","pred":"source","obj":"LitCovid-PubTator"},{"subj":"600","pred":"source","obj":"LitCovid-PubTator"},{"subj":"601","pred":"source","obj":"LitCovid-PubTator"},{"subj":"602","pred":"source","obj":"LitCovid-PubTator"},{"subj":"603","pred":"source","obj":"LitCovid-PubTator"},{"subj":"620","pred":"source","obj":"LitCovid-PubTator"},{"subj":"621","pred":"source","obj":"LitCovid-PubTator"},{"subj":"622","pred":"source","obj":"LitCovid-PubTator"},{"subj":"623","pred":"source","obj":"LitCovid-PubTator"},{"subj":"624","pred":"source","obj":"LitCovid-PubTator"},{"subj":"625","pred":"source","obj":"LitCovid-PubTator"},{"subj":"626","pred":"source","obj":"LitCovid-PubTator"},{"subj":"627","pred":"source","obj":"LitCovid-PubTator"},{"subj":"628","pred":"source","obj":"LitCovid-PubTator"},{"subj":"629","pred":"source","obj":"LitCovid-PubTator"},{"subj":"630","pred":"source","obj":"LitCovid-PubTator"},{"subj":"631","pred":"source","obj":"LitCovid-PubTator"},{"subj":"632","pred":"source","obj":"LitCovid-PubTator"},{"subj":"633","pred":"source","obj":"LitCovid-PubTator"},{"subj":"634","pred":"source","obj":"LitCovid-PubTator"},{"subj":"635","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T264","span":{"begin":0,"end":4},"obj":"Sentence"},{"id":"T265","span":{"begin":6,"end":172},"obj":"Sentence"},{"id":"T266","span":{"begin":173,"end":403},"obj":"Sentence"},{"id":"T267","span":{"begin":404,"end":538},"obj":"Sentence"},{"id":"T268","span":{"begin":539,"end":640},"obj":"Sentence"},{"id":"T269","span":{"begin":641,"end":761},"obj":"Sentence"},{"id":"T270","span":{"begin":762,"end":770},"obj":"Sentence"},{"id":"T271","span":{"begin":772,"end":945},"obj":"Sentence"},{"id":"T272","span":{"begin":946,"end":972},"obj":"Sentence"},{"id":"T273","span":{"begin":973,"end":975},"obj":"Sentence"},{"id":"T274","span":{"begin":976,"end":979},"obj":"Sentence"},{"id":"T275","span":{"begin":981,"end":1021},"obj":"Sentence"},{"id":"T276","span":{"begin":1022,"end":1243},"obj":"Sentence"},{"id":"T277","span":{"begin":1244,"end":1246},"obj":"Sentence"},{"id":"T278","span":{"begin":1248,"end":1300},"obj":"Sentence"},{"id":"T279","span":{"begin":1301,"end":1303},"obj":"Sentence"},{"id":"T280","span":{"begin":1305,"end":1358},"obj":"Sentence"},{"id":"T281","span":{"begin":1359,"end":1361},"obj":"Sentence"},{"id":"T282","span":{"begin":1363,"end":1416},"obj":"Sentence"},{"id":"T283","span":{"begin":1417,"end":1419},"obj":"Sentence"},{"id":"T284","span":{"begin":1421,"end":1474},"obj":"Sentence"},{"id":"T285","span":{"begin":1475,"end":1477},"obj":"Sentence"},{"id":"T286","span":{"begin":1479,"end":1533},"obj":"Sentence"},{"id":"T287","span":{"begin":1534,"end":1536},"obj":"Sentence"},{"id":"T288","span":{"begin":1538,"end":1587},"obj":"Sentence"},{"id":"T289","span":{"begin":1588,"end":1590},"obj":"Sentence"},{"id":"T290","span":{"begin":1592,"end":1649},"obj":"Sentence"},{"id":"T291","span":{"begin":1650,"end":1652},"obj":"Sentence"},{"id":"T292","span":{"begin":1654,"end":1703},"obj":"Sentence"},{"id":"T293","span":{"begin":1704,"end":1706},"obj":"Sentence"},{"id":"T294","span":{"begin":1708,"end":1761},"obj":"Sentence"},{"id":"T295","span":{"begin":1762,"end":1765},"obj":"Sentence"},{"id":"T296","span":{"begin":1767,"end":1813},"obj":"Sentence"},{"id":"T297","span":{"begin":1814,"end":1817},"obj":"Sentence"},{"id":"T298","span":{"begin":1819,"end":1870},"obj":"Sentence"},{"id":"T299","span":{"begin":1871,"end":1874},"obj":"Sentence"},{"id":"T300","span":{"begin":1876,"end":1923},"obj":"Sentence"},{"id":"T301","span":{"begin":1924,"end":1927},"obj":"Sentence"},{"id":"T302","span":{"begin":1929,"end":1971},"obj":"Sentence"},{"id":"T303","span":{"begin":1972,"end":1975},"obj":"Sentence"},{"id":"T304","span":{"begin":1977,"end":2035},"obj":"Sentence"},{"id":"T305","span":{"begin":2036,"end":2039},"obj":"Sentence"},{"id":"T306","span":{"begin":2041,"end":2087},"obj":"Sentence"},{"id":"T307","span":{"begin":2088,"end":2091},"obj":"Sentence"},{"id":"T308","span":{"begin":2093,"end":2141},"obj":"Sentence"},{"id":"T309","span":{"begin":2142,"end":2252},"obj":"Sentence"},{"id":"T310","span":{"begin":2253,"end":2345},"obj":"Sentence"},{"id":"T311","span":{"begin":2346,"end":2419},"obj":"Sentence"},{"id":"T312","span":{"begin":2420,"end":2492},"obj":"Sentence"},{"id":"T313","span":{"begin":2493,"end":2555},"obj":"Sentence"},{"id":"T314","span":{"begin":2556,"end":2687},"obj":"Sentence"},{"id":"T315","span":{"begin":2688,"end":2839},"obj":"Sentence"},{"id":"T316","span":{"begin":2840,"end":2848},"obj":"Sentence"},{"id":"T317","span":{"begin":2850,"end":3029},"obj":"Sentence"},{"id":"T318","span":{"begin":3030,"end":3032},"obj":"Sentence"},{"id":"T319","span":{"begin":3033,"end":3036},"obj":"Sentence"},{"id":"T320","span":{"begin":3038,"end":3118},"obj":"Sentence"},{"id":"T321","span":{"begin":3119,"end":3121},"obj":"Sentence"},{"id":"T322","span":{"begin":3123,"end":3150},"obj":"Sentence"},{"id":"T323","span":{"begin":3151,"end":3153},"obj":"Sentence"},{"id":"T324","span":{"begin":3155,"end":3183},"obj":"Sentence"},{"id":"T325","span":{"begin":3184,"end":3186},"obj":"Sentence"},{"id":"T326","span":{"begin":3188,"end":3216},"obj":"Sentence"},{"id":"T327","span":{"begin":3217,"end":3219},"obj":"Sentence"},{"id":"T328","span":{"begin":3221,"end":3249},"obj":"Sentence"},{"id":"T329","span":{"begin":3250,"end":3252},"obj":"Sentence"},{"id":"T330","span":{"begin":3254,"end":3282},"obj":"Sentence"},{"id":"T331","span":{"begin":3283,"end":3285},"obj":"Sentence"},{"id":"T332","span":{"begin":3287,"end":3311},"obj":"Sentence"},{"id":"T333","span":{"begin":3312,"end":3314},"obj":"Sentence"},{"id":"T334","span":{"begin":3316,"end":3347},"obj":"Sentence"},{"id":"T335","span":{"begin":3348,"end":3350},"obj":"Sentence"},{"id":"T336","span":{"begin":3352,"end":3376},"obj":"Sentence"},{"id":"T337","span":{"begin":3377,"end":3379},"obj":"Sentence"},{"id":"T338","span":{"begin":3381,"end":3408},"obj":"Sentence"},{"id":"T339","span":{"begin":3409,"end":3412},"obj":"Sentence"},{"id":"T340","span":{"begin":3414,"end":3437},"obj":"Sentence"},{"id":"T341","span":{"begin":3438,"end":3441},"obj":"Sentence"},{"id":"T342","span":{"begin":3443,"end":3470},"obj":"Sentence"},{"id":"T343","span":{"begin":3471,"end":3474},"obj":"Sentence"},{"id":"T344","span":{"begin":3476,"end":3501},"obj":"Sentence"},{"id":"T345","span":{"begin":3502,"end":3505},"obj":"Sentence"},{"id":"T346","span":{"begin":3507,"end":3529},"obj":"Sentence"},{"id":"T347","span":{"begin":3530,"end":3533},"obj":"Sentence"},{"id":"T348","span":{"begin":3535,"end":3568},"obj":"Sentence"},{"id":"T349","span":{"begin":3569,"end":3572},"obj":"Sentence"},{"id":"T350","span":{"begin":3574,"end":3599},"obj":"Sentence"},{"id":"T351","span":{"begin":3600,"end":3603},"obj":"Sentence"},{"id":"T352","span":{"begin":3605,"end":3630},"obj":"Sentence"},{"id":"T353","span":{"begin":3631,"end":3651},"obj":"Sentence"},{"id":"T354","span":{"begin":3652,"end":3666},"obj":"Sentence"},{"id":"T355","span":{"begin":3667,"end":3693},"obj":"Sentence"},{"id":"T356","span":{"begin":3694,"end":3717},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T264","pred":"source","obj":"LitCovid-sentences"},{"subj":"T265","pred":"source","obj":"LitCovid-sentences"},{"subj":"T266","pred":"source","obj":"LitCovid-sentences"},{"subj":"T267","pred":"source","obj":"LitCovid-sentences"},{"subj":"T268","pred":"source","obj":"LitCovid-sentences"},{"subj":"T269","pred":"source","obj":"LitCovid-sentences"},{"subj":"T270","pred":"source","obj":"LitCovid-sentences"},{"subj":"T271","pred":"source","obj":"LitCovid-sentences"},{"subj":"T272","pred":"source","obj":"LitCovid-sentences"},{"subj":"T273","pred":"source","obj":"LitCovid-sentences"},{"subj":"T274","pred":"source","obj":"LitCovid-sentences"},{"subj":"T275","pred":"source","obj":"LitCovid-sentences"},{"subj":"T276","pred":"source","obj":"LitCovid-sentences"},{"subj":"T277","pred":"source","obj":"LitCovid-sentences"},{"subj":"T278","pred":"source","obj":"LitCovid-sentences"},{"subj":"T279","pred":"source","obj":"LitCovid-sentences"},{"subj":"T280","pred":"source","obj":"LitCovid-sentences"},{"subj":"T281","pred":"source","obj":"LitCovid-sentences"},{"subj":"T282","pred":"source","obj":"LitCovid-sentences"},{"subj":"T283","pred":"source","obj":"LitCovid-sentences"},{"subj":"T284","pred":"source","obj":"LitCovid-sentences"},{"subj":"T285","pred":"source","obj":"LitCovid-sentences"},{"subj":"T286","pred":"source","obj":"LitCovid-sentences"},{"subj":"T287","pred":"source","obj":"LitCovid-sentences"},{"subj":"T288","pred":"source","obj":"LitCovid-sentences"},{"subj":"T289","pred":"source","obj":"LitCovid-sentences"},{"subj":"T290","pred":"source","obj":"LitCovid-sentences"},{"subj":"T291","pred":"source","obj":"LitCovid-sentences"},{"subj":"T292","pred":"source","obj":"LitCovid-sentences"},{"subj":"T293","pred":"source","obj":"LitCovid-sentences"},{"subj":"T294","pred":"source","obj":"LitCovid-sentences"},{"subj":"T295","pred":"source","obj":"LitCovid-sentences"},{"subj":"T296","pred":"source","obj":"LitCovid-sentences"},{"subj":"T297","pred":"source","obj":"LitCovid-sentences"},{"subj":"T298","pred":"source","obj":"LitCovid-sentences"},{"subj":"T299","pred":"source","obj":"LitCovid-sentences"},{"subj":"T300","pred":"source","obj":"LitCovid-sentences"},{"subj":"T301","pred":"source","obj":"LitCovid-sentences"},{"subj":"T302","pred":"source","obj":"LitCovid-sentences"},{"subj":"T303","pred":"source","obj":"LitCovid-sentences"},{"subj":"T304","pred":"source","obj":"LitCovid-sentences"},{"subj":"T305","pred":"source","obj":"LitCovid-sentences"},{"subj":"T306","pred":"source","obj":"LitCovid-sentences"},{"subj":"T307","pred":"source","obj":"LitCovid-sentences"},{"subj":"T308","pred":"source","obj":"LitCovid-sentences"},{"subj":"T309","pred":"source","obj":"LitCovid-sentences"},{"subj":"T310","pred":"source","obj":"LitCovid-sentences"},{"subj":"T311","pred":"source","obj":"LitCovid-sentences"},{"subj":"T312","pred":"source","obj":"LitCovid-sentences"},{"subj":"T313","pred":"source","obj":"LitCovid-sentences"},{"subj":"T314","pred":"source","obj":"LitCovid-sentences"},{"subj":"T315","pred":"source","obj":"LitCovid-sentences"},{"subj":"T316","pred":"source","obj":"LitCovid-sentences"},{"subj":"T317","pred":"source","obj":"LitCovid-sentences"},{"subj":"T318","pred":"source","obj":"LitCovid-sentences"},{"subj":"T319","pred":"source","obj":"LitCovid-sentences"},{"subj":"T320","pred":"source","obj":"LitCovid-sentences"},{"subj":"T321","pred":"source","obj":"LitCovid-sentences"},{"subj":"T322","pred":"source","obj":"LitCovid-sentences"},{"subj":"T323","pred":"source","obj":"LitCovid-sentences"},{"subj":"T324","pred":"source","obj":"LitCovid-sentences"},{"subj":"T325","pred":"source","obj":"LitCovid-sentences"},{"subj":"T326","pred":"source","obj":"LitCovid-sentences"},{"subj":"T327","pred":"source","obj":"LitCovid-sentences"},{"subj":"T328","pred":"source","obj":"LitCovid-sentences"},{"subj":"T329","pred":"source","obj":"LitCovid-sentences"},{"subj":"T330","pred":"source","obj":"LitCovid-sentences"},{"subj":"T331","pred":"source","obj":"LitCovid-sentences"},{"subj":"T332","pred":"source","obj":"LitCovid-sentences"},{"subj":"T333","pred":"source","obj":"LitCovid-sentences"},{"subj":"T334","pred":"source","obj":"LitCovid-sentences"},{"subj":"T335","pred":"source","obj":"LitCovid-sentences"},{"subj":"T336","pred":"source","obj":"LitCovid-sentences"},{"subj":"T337","pred":"source","obj":"LitCovid-sentences"},{"subj":"T338","pred":"source","obj":"LitCovid-sentences"},{"subj":"T339","pred":"source","obj":"LitCovid-sentences"},{"subj":"T340","pred":"source","obj":"LitCovid-sentences"},{"subj":"T341","pred":"source","obj":"LitCovid-sentences"},{"subj":"T342","pred":"source","obj":"LitCovid-sentences"},{"subj":"T343","pred":"source","obj":"LitCovid-sentences"},{"subj":"T344","pred":"source","obj":"LitCovid-sentences"},{"subj":"T345","pred":"source","obj":"LitCovid-sentences"},{"subj":"T346","pred":"source","obj":"LitCovid-sentences"},{"subj":"T347","pred":"source","obj":"LitCovid-sentences"},{"subj":"T348","pred":"source","obj":"LitCovid-sentences"},{"subj":"T349","pred":"source","obj":"LitCovid-sentences"},{"subj":"T350","pred":"source","obj":"LitCovid-sentences"},{"subj":"T351","pred":"source","obj":"LitCovid-sentences"},{"subj":"T352","pred":"source","obj":"LitCovid-sentences"},{"subj":"T353","pred":"source","obj":"LitCovid-sentences"},{"subj":"T354","pred":"source","obj":"LitCovid-sentences"},{"subj":"T355","pred":"source","obj":"LitCovid-sentences"},{"subj":"T356","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#ec93ce","default":true},{"id":"LitCovid-sentences","color":"#93e8ec"}]}]}}