PMC:7755033 / 13417-14014
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7755033","sourcedb":"PMC","sourceid":"7755033","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7755033","text":"Agents that can preferentially bind to ACE2 receptor can be thought of as promising ‘preventive’ agents against SARS-CoV-2 infection. Alternately, agents that bind to main viral proteins can interfere and/or block crucial stages in the viral life cycle such as viral entry, replication, membrane fusion and hence, can function as promising therapeutic agents. The present paper attempts to highlight the preventive/therapeutic potential of withanolides from WS as promising antiviral agents to augment our limited armamentarium of drugs available against SARS-CoV-2 to effectively combat COVID-19.","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"288","span":{"begin":39,"end":43},"obj":"Gene"},{"id":"289","span":{"begin":555,"end":565},"obj":"Species"},{"id":"290","span":{"begin":458,"end":460},"obj":"Species"},{"id":"291","span":{"begin":440,"end":452},"obj":"Chemical"},{"id":"292","span":{"begin":112,"end":132},"obj":"Disease"},{"id":"293","span":{"begin":588,"end":596},"obj":"Disease"}],"attributes":[{"id":"A288","pred":"tao:has_database_id","subj":"288","obj":"Gene:59272"},{"id":"A289","pred":"tao:has_database_id","subj":"289","obj":"Tax:2697049"},{"id":"A290","pred":"tao:has_database_id","subj":"290","obj":"Tax:126910"},{"id":"A291","pred":"tao:has_database_id","subj":"291","obj":"MESH:D054358"},{"id":"A292","pred":"tao:has_database_id","subj":"292","obj":"MESH:C000657245"},{"id":"A293","pred":"tao:has_database_id","subj":"293","obj":"MESH:C000657245"},{"subj":"288","pred":"source","obj":"LitCovid-PubTator"},{"subj":"289","pred":"source","obj":"LitCovid-PubTator"},{"subj":"290","pred":"source","obj":"LitCovid-PubTator"},{"subj":"291","pred":"source","obj":"LitCovid-PubTator"},{"subj":"292","pred":"source","obj":"LitCovid-PubTator"},{"subj":"293","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T118","span":{"begin":0,"end":133},"obj":"Sentence"},{"id":"T119","span":{"begin":134,"end":359},"obj":"Sentence"},{"id":"T120","span":{"begin":360,"end":597},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T118","pred":"source","obj":"LitCovid-sentences"},{"subj":"T119","pred":"source","obj":"LitCovid-sentences"},{"subj":"T120","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#ec93cb","default":true},{"id":"LitCovid-sentences","color":"#93e6ec"}]}]}}