PMC:7736111 / 109038-109935 JSONTXT

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LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T27 444-459 Phenotype denotes lymphocytopenia http://purl.obolibrary.org/obo/HP_0001888

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2509 228-231 Gene denotes CD8 Gene:925
2510 637-642 Gene denotes CD11a Gene:3683
2511 700-703 Gene denotes CD4 Gene:920
2512 709-712 Gene denotes CD8 Gene:925
2513 28-36 Species denotes patients Tax:9606
2514 290-298 Species denotes patients Tax:9606
2515 597-605 Species denotes patients Tax:9606
2516 19-27 Disease denotes COVID-19 MESH:C000657245
2517 444-459 Disease denotes lymphocytopenia MESH:D008231
2518 588-596 Disease denotes COVID-19 MESH:C000657245
2519 852-860 Disease denotes infected MESH:D007239

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T644 0-186 Sentence denotes Immune profiles of COVID-19 patients show adequate levels of chemokines and cytokines involved in the maintenance of T and B cell phenotypes (Yang X. et al., 2020; Yang Y. et al., 2020).
T645 187-299 Sentence denotes Chemokines and cytokines responsible for CD8+ T cells priming and chemotaxis were also detected in the patients.
T646 300-530 Sentence denotes Similarly, cytokines responsible for B cell activation and proliferation signals were sufficiently present, thus excluding the possibility that lymphocytopenia may be a result of impaired activation signals or chemokine signaling.
T647 531-758 Sentence denotes Interestingly, a recent study suggests that severely ill COVID-19 patients had lower levels of activated (CD11a+) and terminally differentiated (CD57+) peripheral blood CD4+ and CD8+ T cells (which are also S-protein reactive).
T648 759-897 Sentence denotes The decline in the number of these cells can attribute to their concomitant migration to the infected regions under inflammatory response.