PMC:7712180 / 28579-29550 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
981	131-152	Gene	denotes	alpha 1-macroglobulin	Gene:252922
982	183-188	Gene	denotes	mucin	Gene:281333
983	254-267	Gene	denotes	neuraminidase	Gene:4758
984	651-660	Gene	denotes	Neu5,9Ac2
985	127-130	Species	denotes	rat	Tax:10116
986	163-169	Species	denotes	bovine	Tax:9913
987	273-287	Species	denotes	A. ureafaciens	Tax:37931
988	210-213	Species	denotes	ICV	Tax:11552
989	329-332	Species	denotes	ICV	Tax:11552
990	503-506	Species	denotes	ICV	Tax:11552
991	778-781	Species	denotes	ICV	Tax:11552
992	872-875	Species	denotes	ICV	Tax:11552
993	947-950	Species	denotes	ICV	Tax:11552
994	688-694	Chemical	denotes	Neu5Ac
995	855-858	Chemical	denotes	RMG

Id	Subject	Object	Predicate	Lexical cue
T170	0-402	Sentence	denotes	Thin-layer chromatography (TLC), gas-liquid chromatography (GLC) and high-performance liquid chromatography (HPLC) analyses of rat alpha 1-macroglobulin (RMG) and bovine submaxillary mucin (BSM) incubated with ICV in comparison with those incubated with neuraminidase from A. ureafaciens revealed that RMG and BSM incubated with ICV have a reduced amount of Neu5,9Ac2 but an increased amount of Neu5Ac.
T171	403-721	Sentence	denotes	After confirmation by using purified Neu5,9Ac2 instead of RMG and BSM, it was concluded that RDE of ICV is neuraminate O-acetylesterase (9-O-acetyl N-acetylneuraminate O-acetylhydrolase (EC 3.1.1.53) catalyzing removal of the 9-O-acetyl group from Neu5,9Ac2, not cleaving the terminal Neu5Ac from glycoconjugate [182].
T172	722-890	Sentence	denotes	RMG and BSM can potentially inhibit hemagglutination by ICV at 4oC, and their inhibitory effects were abolished by pre-incubation of RMG and BSM with ICV at 37oC [182].
T173	891-971	Sentence	denotes	This evidence suggested that Neu5,9Ac2 is a receptor of ICV on the cell surface.