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PMC:7696151 / 7129-7784 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
178 0-3 Chemical denotes HCQ MESH:D006886
179 109-112 Chemical denotes HCQ MESH:D006886
180 313-316 Chemical denotes HCQ MESH:D006886
181 91-107 Disease denotes viral infections MESH:D001102
182 253-262 Disease denotes infection MESH:D007239
183 645-654 Disease denotes infection MESH:D007239

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T63 0-108 Sentence denotes HCQ has been used mainly as an antimalarial drug, but it has also proven effective against viral infections.
T64 109-297 Sentence denotes HCQ demonstrated its antiviral efficacy in inhibiting the endosomal-lysosomal acidification, which is essential for the entry, replication, and infection process of different viruses [12].
T65 298-429 Sentence denotes In particular, HCQ-induced alkalinization processes cause the expansion and vacuolization of lysosomes, inhibiting their functions.
T66 430-599 Sentence denotes This activity can reduce post-transcriptional protein modification, enzyme release, receptor recycling, activation of cell signaling pathways, and cell membranes repair.
T67 600-655 Sentence denotes As a result, there is the prevention of cell infection.