PMC:7696151 / 41501-42051 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
1175	282-285	Chemical	denotes	HCQ	MESH:D006886
1176	169-189	Disease	denotes	rheumatoid arthritis	MESH:D001172
1177	191-210	Disease	denotes	lupus erythematosus	MESH:D008180
1178	220-238	Disease	denotes	Sjögren’s syndrome	MESH:D012859
1179	363-420	Disease	denotes	autoimmune disease-dependent cardiovascular complications	MESH:D002318
1180	487-500	Disease	denotes	hyperglycemia	MESH:D006943
1181	502-516	Disease	denotes	hyperlipidemia	MESH:D006949

Id	Subject	Object	Predicate	Lexical cue	hp_id
T55	142-162	Phenotype	denotes	auto-immune diseases	http://purl.obolibrary.org/obo/HP_0002960
T56	169-189	Phenotype	denotes	rheumatoid arthritis	http://purl.obolibrary.org/obo/HP_0001370
T57	363-381	Phenotype	denotes	autoimmune disease	http://purl.obolibrary.org/obo/HP_0002960
T58	487-500	Phenotype	denotes	hyperglycemia	http://purl.obolibrary.org/obo/HP_0003074
T59	502-516	Phenotype	denotes	hyperlipidemia	http://purl.obolibrary.org/obo/HP_0003077

Id	Subject	Object	Predicate	Lexical cue
T269	0-271	Sentence	denotes	Most of all, it showed immunosuppressive properties, allowing its employment (alone or in combination) in the first-line treatment of several auto-immune diseases, like rheumatoid arthritis, lupus erythematosus, primary Sjögren’s syndrome, and anti-phospholipid syndrome.
T270	272-550	Sentence	denotes	Moreover, HCQ was revealed to be effective in preclinical and clinical trials to dampening autoimmune disease-dependent cardiovascular complications (Figure 7), as well as in the amelioration of disease-independent hyperglycemia, hyperlipidemia, and gastrointestinal complaints.