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PMC:7696151 / 3520-4065 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
106 10-15 Chemical denotes water MESH:D014867
107 146-149 Chemical denotes HCQ MESH:D006886
108 225-227 Chemical denotes CQ MESH:D002738
109 232-235 Chemical denotes HCQ MESH:D006886
110 386-391 Chemical denotes R-HCQ
111 446-451 Chemical denotes S-HCQ

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T29 0-194 Sentence denotes These are water-soluble molecules and, for their chemical nature, can pass the cell membranes; however, the presence of the hydroxyl group in the HCQ makes it more polar and less lipophilic [8].
T30 195-347 Sentence denotes Moreover, the accumulation of CQ and HCQ in intracellular compartments is due principally to the side chain and both have enantiomers (R and S isomers).
T31 348-452 Sentence denotes Researches also demonstrated that the R-HCQ is present in the blood at higher concentrations than S-HCQ.
T32 453-545 Sentence denotes These results suggested the stereoselective processes in the metabolism of the molecule [9].