PMC:7652766 / 110334-110686 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7652766","sourcedb":"PMC","sourceid":"7652766","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7652766","text":"Although the in vitro proliferation inhibition effect of Ivermectin against SARS-CoV-2 has been shown, there is no evidence that the IC50 of ~ 2 µM determined by Caly and colleagues can be achieved in the clinic where pharmacokinetics studies showed that even the maximum tested dosage of 1700 μg/kg presented only 0.28μM of plasma concentration (390).","tracks":[{"project":"LitCovid-sentences","denotations":[{"id":"T543","span":{"begin":0,"end":352},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T543","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"4072","span":{"begin":162,"end":166},"obj":"Gene"},{"id":"4073","span":{"begin":76,"end":86},"obj":"Species"}],"attributes":[{"id":"A4072","pred":"tao:has_database_id","subj":"4072","obj":"Gene:50632"},{"id":"A4073","pred":"tao:has_database_id","subj":"4073","obj":"Tax:2697049"},{"subj":"4072","pred":"source","obj":"LitCovid-PubTator"},{"subj":"4073","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-sentences","color":"#ec93ac","default":true},{"id":"LitCovid-PubTator","color":"#93c6ec"}]}]}}