PMC:7652766 / 101559-102075 JSONTXT

{"project":"LitCovid-PD-HP","denotations":[{"id":"T137","span":{"begin":397,"end":406},"obj":"Phenotype"}],"attributes":[{"id":"A137","pred":"hp_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"In vitro studies on SARS-CoV-2 have demonstrated the low-dose action of these drugs, having found the lowest half-maximal effective concentrations (EC50s). In addition, their association with azithromycin significantly inhibited viral replication (326, 360–362). In humans, a study by Gao, Tian, and Yang (363) showed that patients treated with chloroquine phosphate had inhibited exacerbation of pneumonia, improving lung imaging findings, promoting a virus-negative conversion, and shortening the COVID-19 course.\n"}

{"project":"LitCovid-sentences","denotations":[{"id":"T496","span":{"begin":0,"end":155},"obj":"Sentence"},{"id":"T497","span":{"begin":156,"end":262},"obj":"Sentence"},{"id":"T498","span":{"begin":263,"end":515},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In vitro studies on SARS-CoV-2 have demonstrated the low-dose action of these drugs, having found the lowest half-maximal effective concentrations (EC50s). In addition, their association with azithromycin significantly inhibited viral replication (326, 360–362). In humans, a study by Gao, Tian, and Yang (363) showed that patients treated with chloroquine phosphate had inhibited exacerbation of pneumonia, improving lung imaging findings, promoting a virus-negative conversion, and shortening the COVID-19 course.\n"}

{"project":"LitCovid-PubTator","denotations":[{"id":"3721","span":{"begin":20,"end":30},"obj":"Species"},{"id":"3722","span":{"begin":266,"end":272},"obj":"Species"},{"id":"3723","span":{"begin":323,"end":331},"obj":"Species"},{"id":"3724","span":{"begin":451,"end":452},"obj":"Gene"},{"id":"3725","span":{"begin":274,"end":275},"obj":"Gene"},{"id":"3726","span":{"begin":192,"end":204},"obj":"Chemical"},{"id":"3727","span":{"begin":345,"end":366},"obj":"Chemical"},{"id":"3728","span":{"begin":397,"end":406},"obj":"Disease"},{"id":"3729","span":{"begin":499,"end":507},"obj":"Disease"}],"attributes":[{"id":"A3721","pred":"tao:has_database_id","subj":"3721","obj":"Tax:2697049"},{"id":"A3722","pred":"tao:has_database_id","subj":"3722","obj":"Tax:9606"},{"id":"A3723","pred":"tao:has_database_id","subj":"3723","obj":"Tax:9606"},{"id":"A3724","pred":"tao:has_database_id","subj":"3724","obj":"Gene:351"},{"id":"A3725","pred":"tao:has_database_id","subj":"3725","obj":"Gene:351"},{"id":"A3726","pred":"tao:has_database_id","subj":"3726","obj":"MESH:D017963"},{"id":"A3727","pred":"tao:has_database_id","subj":"3727","obj":"MESH:C023676"},{"id":"A3728","pred":"tao:has_database_id","subj":"3728","obj":"MESH:D011014"},{"id":"A3729","pred":"tao:has_database_id","subj":"3729","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In vitro studies on SARS-CoV-2 have demonstrated the low-dose action of these drugs, having found the lowest half-maximal effective concentrations (EC50s). In addition, their association with azithromycin significantly inhibited viral replication (326, 360–362). In humans, a study by Gao, Tian, and Yang (363) showed that patients treated with chloroquine phosphate had inhibited exacerbation of pneumonia, improving lung imaging findings, promoting a virus-negative conversion, and shortening the COVID-19 course.\n"}