PMC:7650537 / 3801-5459
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T25 | 81-88 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T26 | 130-137 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T27 | 240-248 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T28 | 353-360 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T29 | 420-428 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T30 | 809-825 | Body_part | denotes | immunoglobulin G | http://purl.org/sig/ont/fma/fma62872 |
| T31 | 827-830 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T32 | 1074-1077 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T33 | 1139-1142 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T34 | 1166-1173 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T35 | 1209-1216 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T36 | 1428-1431 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T37 | 1472-1480 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T38 | 1561-1569 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T22 | 261-265 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T23 | 409-417 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T24 | 586-594 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T25 | 597-606 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T26 | 798-806 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T27 | 874-882 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T28 | 994-1002 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T29 | 1453-1461 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T27 | 294-295 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T28 | 332-337 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
| T29 | 429-434 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
| T30 | 511-516 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T31 | 584-585 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T32 | 677-682 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T33 | 781-782 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T34 | 1092-1097 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focus |
| T35 | 1122-1123 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T36 | 1304-1309 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T37 | 1624-1629 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T17 | 81-88 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T18 | 130-137 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T19 | 353-360 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T20 | 368-375 | Chemical | denotes | antigen | http://purl.obolibrary.org/obo/CHEBI_59132 |
| T21 | 1166-1173 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T22 | 1209-1216 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T23 | 1472-1480 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T30 | 0-218 | Sentence | denotes | It is believed that the majority of antibodies are raised against the abundant N protein, while antibodies directed against the S protein are considered more specific and correlate with the neutralizing capacity [7,8]. |
| T31 | 219-384 | Sentence | denotes | Earlier works on the antibody response in SARS (2002/2003) patients showed a significantly higher sensitivity of tests based on the N protein as the antigen [10,11]. |
| T32 | 385-531 | Sentence | denotes | The diagnostic value of SARS-CoV-2 antibody tests, however, may be limited due to their potential cross-reactivity with other human coronaviruses. |
| T33 | 532-618 | Sentence | denotes | So far, the duration of the acquired immunity after a SARS-CoV-2 infection is unclear. |
| T34 | 619-755 | Sentence | denotes | However, based on experience with reinfections from other human coronaviruses, it remains yet open if the immunity is long-lasting [12]. |
| T35 | 756-1010 | Sentence | denotes | Several studies reported a rapid decay of SARS-CoV-2 immunoglobulin G (IgG) in asymptomatic individuals [13] and mild COVID-19 cases [14] but, more surprisingly, also in hospitalized patients presenting with the full clinical spectrum of COVID-19 [5,15]. |
| T36 | 1011-1115 | Sentence | denotes | Very recently, differences in the kinetics of N- or S-specific IgG came into the focus of research [16]. |
| T37 | 1116-1339 | Sentence | denotes | While a decline in the IgG directed against the N protein was evident, the response to the S protein or its RBD was found to be more stable [16,17] and was associated with the presence of virus-neutralizing antibodies [17]. |
| T38 | 1340-1511 | Sentence | denotes | To the best of our knowledge, clinically validated assays for the specific detection of IgG directed against the SARS-CoV-2 surface proteins E and M are not yet available. |
| T39 | 1512-1658 | Sentence | denotes | However, it would make sense to investigate such antibody responses as well, since they can also correlate with virus-neutralizing capacities [4]. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 89 | 128-129 | Gene | denotes | S | Gene:43740568 |
| 90 | 1481-1482 | Gene | denotes | E | Gene:43740570 |
| 91 | 79-80 | Gene | denotes | N | Gene:43740575 |
| 92 | 1207-1208 | Gene | denotes | S | Gene:43740568 |
| 93 | 1063-1064 | Gene | denotes | S | Gene:43740568 |
| 94 | 278-286 | Species | denotes | patients | Tax:9606 |
| 95 | 511-516 | Species | denotes | human | Tax:9606 |
| 96 | 517-530 | Species | denotes | coronaviruses | Tax:11118 |
| 97 | 677-682 | Species | denotes | human | Tax:9606 |
| 98 | 683-696 | Species | denotes | coronaviruses | Tax:11118 |
| 99 | 798-808 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 100 | 939-947 | Species | denotes | patients | Tax:9606 |
| 101 | 1453-1463 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 102 | 409-419 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 103 | 586-606 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
| 104 | 874-882 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 105 | 994-1002 | Disease | denotes | COVID-19 | MESH:C000657245 |