PMC:7650537 / 1569-2605 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T14","span":{"begin":431,"end":447},"obj":"Body_part"},{"id":"T15","span":{"begin":449,"end":452},"obj":"Body_part"},{"id":"T16","span":{"begin":454,"end":460},"obj":"Body_part"},{"id":"T17","span":{"begin":508,"end":516},"obj":"Body_part"},{"id":"T18","span":{"begin":573,"end":581},"obj":"Body_part"},{"id":"T19","span":{"begin":601,"end":606},"obj":"Body_part"},{"id":"T20","span":{"begin":622,"end":630},"obj":"Body_part"},{"id":"T21","span":{"begin":900,"end":903},"obj":"Body_part"},{"id":"T22","span":{"begin":944,"end":951},"obj":"Body_part"}],"attributes":[{"id":"A14","pred":"fma_id","subj":"T14","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A15","pred":"fma_id","subj":"T15","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A19","pred":"fma_id","subj":"T19","obj":"http://purl.org/sig/ont/fma/fma67264"},{"id":"A20","pred":"fma_id","subj":"T20","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A21","pred":"fma_id","subj":"T21","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A22","pred":"fma_id","subj":"T22","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"By the end of the year, 2019, Chinese local health authorities reported the occurrence of a cluster of pneumonia cases in Wuhan in the Hubei Province [1]. Shortly after, a novel beta coronavirus—which is now designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]—was discovered in the bronchoalveolar lavage fluid of a patient with pneumonia [1,3]. This enveloped virus has a single-stranded positive sense ribonucleic acid (RNA) genome of approximately 30 kilobases. Several surface proteins, known as the spike (S), envelope (E), and membrane (M) proteins, are embedded in a lipid bilayer. These proteins mediate the viral entry (S; S1 unit: binding to host receptor angiotensin-converting enzyme 2 via its receptor binding domain (RBD) and S2 unit: membrane fusion) and are also responsible for viral fusion (M), morphogenesis (E), assembly (E and M), and budding (M). The RNA is associated with the nucleocapsid (N) protein. The latter plays a role in the viral replication and transcription cycle [4,5,6,7]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T9","span":{"begin":103,"end":112},"obj":"Disease"},{"id":"T10","span":{"begin":222,"end":269},"obj":"Disease"},{"id":"T11","span":{"begin":222,"end":255},"obj":"Disease"},{"id":"T12","span":{"begin":271,"end":279},"obj":"Disease"},{"id":"T13","span":{"begin":356,"end":365},"obj":"Disease"}],"attributes":[{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"}],"text":"By the end of the year, 2019, Chinese local health authorities reported the occurrence of a cluster of pneumonia cases in Wuhan in the Hubei Province [1]. Shortly after, a novel beta coronavirus—which is now designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]—was discovered in the bronchoalveolar lavage fluid of a patient with pneumonia [1,3]. This enveloped virus has a single-stranded positive sense ribonucleic acid (RNA) genome of approximately 30 kilobases. Several surface proteins, known as the spike (S), envelope (E), and membrane (M) proteins, are embedded in a lipid bilayer. These proteins mediate the viral entry (S; S1 unit: binding to host receptor angiotensin-converting enzyme 2 via its receptor binding domain (RBD) and S2 unit: membrane fusion) and are also responsible for viral fusion (M), morphogenesis (E), assembly (E and M), and budding (M). The RNA is associated with the nucleocapsid (N) protein. The latter plays a role in the viral replication and transcription cycle [4,5,6,7]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T8","span":{"begin":90,"end":91},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T9","span":{"begin":170,"end":171},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T10","span":{"begin":341,"end":342},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T11","span":{"begin":388,"end":393},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T12","span":{"begin":394,"end":397},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T13","span":{"begin":398,"end":399},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T14","span":{"begin":560,"end":568},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T15","span":{"begin":599,"end":600},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T16","span":{"begin":656,"end":661},"obj":"http://purl.obolibrary.org/obo/CLO_0009133"},{"id":"T17","span":{"begin":767,"end":769},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T18","span":{"begin":767,"end":769},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"},{"id":"T19","span":{"begin":776,"end":784},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T20","span":{"begin":970,"end":971},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"By the end of the year, 2019, Chinese local health authorities reported the occurrence of a cluster of pneumonia cases in Wuhan in the Hubei Province [1]. Shortly after, a novel beta coronavirus—which is now designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]—was discovered in the bronchoalveolar lavage fluid of a patient with pneumonia [1,3]. This enveloped virus has a single-stranded positive sense ribonucleic acid (RNA) genome of approximately 30 kilobases. Several surface proteins, known as the spike (S), envelope (E), and membrane (M) proteins, are embedded in a lipid bilayer. These proteins mediate the viral entry (S; S1 unit: binding to host receptor angiotensin-converting enzyme 2 via its receptor binding domain (RBD) and S2 unit: membrane fusion) and are also responsible for viral fusion (M), morphogenesis (E), assembly (E and M), and budding (M). The RNA is associated with the nucleocapsid (N) protein. The latter plays a role in the viral replication and transcription cycle [4,5,6,7]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T4","span":{"begin":178,"end":182},"obj":"Chemical"},{"id":"T5","span":{"begin":431,"end":447},"obj":"Chemical"},{"id":"T6","span":{"begin":443,"end":447},"obj":"Chemical"},{"id":"T7","span":{"begin":449,"end":452},"obj":"Chemical"},{"id":"T8","span":{"begin":508,"end":516},"obj":"Chemical"},{"id":"T9","span":{"begin":573,"end":581},"obj":"Chemical"},{"id":"T10","span":{"begin":601,"end":606},"obj":"Chemical"},{"id":"T11","span":{"begin":622,"end":630},"obj":"Chemical"},{"id":"T12","span":{"begin":693,"end":704},"obj":"Chemical"},{"id":"T13","span":{"begin":767,"end":769},"obj":"Chemical"},{"id":"T14","span":{"begin":900,"end":903},"obj":"Chemical"},{"id":"T15","span":{"begin":944,"end":951},"obj":"Chemical"}],"attributes":[{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_10545"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_33697"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_33697"},{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A9","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_18059"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_33697"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"By the end of the year, 2019, Chinese local health authorities reported the occurrence of a cluster of pneumonia cases in Wuhan in the Hubei Province [1]. Shortly after, a novel beta coronavirus—which is now designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]—was discovered in the bronchoalveolar lavage fluid of a patient with pneumonia [1,3]. This enveloped virus has a single-stranded positive sense ribonucleic acid (RNA) genome of approximately 30 kilobases. Several surface proteins, known as the spike (S), envelope (E), and membrane (M) proteins, are embedded in a lipid bilayer. These proteins mediate the viral entry (S; S1 unit: binding to host receptor angiotensin-converting enzyme 2 via its receptor binding domain (RBD) and S2 unit: membrane fusion) and are also responsible for viral fusion (M), morphogenesis (E), assembly (E and M), and budding (M). The RNA is associated with the nucleocapsid (N) protein. The latter plays a role in the viral replication and transcription cycle [4,5,6,7]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":776,"end":791},"obj":"http://purl.obolibrary.org/obo/GO_0061025"},{"id":"T2","span":{"begin":840,"end":853},"obj":"http://purl.obolibrary.org/obo/GO_0009653"},{"id":"T3","span":{"begin":883,"end":890},"obj":"http://purl.obolibrary.org/obo/GO_0007114"},{"id":"T4","span":{"begin":984,"end":1001},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T5","span":{"begin":984,"end":1001},"obj":"http://purl.obolibrary.org/obo/GO_0019058"},{"id":"T6","span":{"begin":1006,"end":1019},"obj":"http://purl.obolibrary.org/obo/GO_0006351"}],"text":"By the end of the year, 2019, Chinese local health authorities reported the occurrence of a cluster of pneumonia cases in Wuhan in the Hubei Province [1]. Shortly after, a novel beta coronavirus—which is now designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]—was discovered in the bronchoalveolar lavage fluid of a patient with pneumonia [1,3]. This enveloped virus has a single-stranded positive sense ribonucleic acid (RNA) genome of approximately 30 kilobases. Several surface proteins, known as the spike (S), envelope (E), and membrane (M) proteins, are embedded in a lipid bilayer. These proteins mediate the viral entry (S; S1 unit: binding to host receptor angiotensin-converting enzyme 2 via its receptor binding domain (RBD) and S2 unit: membrane fusion) and are also responsible for viral fusion (M), morphogenesis (E), assembly (E and M), and budding (M). The RNA is associated with the nucleocapsid (N) protein. The latter plays a role in the viral replication and transcription cycle [4,5,6,7]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T15","span":{"begin":0,"end":154},"obj":"Sentence"},{"id":"T16","span":{"begin":155,"end":372},"obj":"Sentence"},{"id":"T17","span":{"begin":373,"end":491},"obj":"Sentence"},{"id":"T18","span":{"begin":492,"end":615},"obj":"Sentence"},{"id":"T19","span":{"begin":616,"end":895},"obj":"Sentence"},{"id":"T20","span":{"begin":896,"end":952},"obj":"Sentence"},{"id":"T21","span":{"begin":953,"end":1036},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"By the end of the year, 2019, Chinese local health authorities reported the occurrence of a cluster of pneumonia cases in Wuhan in the Hubei Province [1]. Shortly after, a novel beta coronavirus—which is now designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]—was discovered in the bronchoalveolar lavage fluid of a patient with pneumonia [1,3]. This enveloped virus has a single-stranded positive sense ribonucleic acid (RNA) genome of approximately 30 kilobases. Several surface proteins, known as the spike (S), envelope (E), and membrane (M) proteins, are embedded in a lipid bilayer. These proteins mediate the viral entry (S; S1 unit: binding to host receptor angiotensin-converting enzyme 2 via its receptor binding domain (RBD) and S2 unit: membrane fusion) and are also responsible for viral fusion (M), morphogenesis (E), assembly (E and M), and budding (M). The RNA is associated with the nucleocapsid (N) protein. The latter plays a role in the viral replication and transcription cycle [4,5,6,7]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":103,"end":112},"obj":"Phenotype"},{"id":"T2","span":{"begin":356,"end":365},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"By the end of the year, 2019, Chinese local health authorities reported the occurrence of a cluster of pneumonia cases in Wuhan in the Hubei Province [1]. Shortly after, a novel beta coronavirus—which is now designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]—was discovered in the bronchoalveolar lavage fluid of a patient with pneumonia [1,3]. This enveloped virus has a single-stranded positive sense ribonucleic acid (RNA) genome of approximately 30 kilobases. Several surface proteins, known as the spike (S), envelope (E), and membrane (M) proteins, are embedded in a lipid bilayer. These proteins mediate the viral entry (S; S1 unit: binding to host receptor angiotensin-converting enzyme 2 via its receptor binding domain (RBD) and S2 unit: membrane fusion) and are also responsible for viral fusion (M), morphogenesis (E), assembly (E and M), and budding (M). The RNA is associated with the nucleocapsid (N) protein. The latter plays a role in the viral replication and transcription cycle [4,5,6,7]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"37","span":{"begin":531,"end":536},"obj":"Gene"},{"id":"38","span":{"begin":538,"end":539},"obj":"Gene"},{"id":"39","span":{"begin":693,"end":724},"obj":"Gene"},{"id":"40","span":{"begin":855,"end":856},"obj":"Gene"},{"id":"41","span":{"begin":869,"end":870},"obj":"Gene"},{"id":"42","span":{"begin":656,"end":657},"obj":"Gene"},{"id":"43","span":{"begin":178,"end":194},"obj":"Species"},{"id":"44","span":{"begin":222,"end":269},"obj":"Species"},{"id":"45","span":{"begin":271,"end":281},"obj":"Species"},{"id":"46","span":{"begin":343,"end":350},"obj":"Species"},{"id":"47","span":{"begin":601,"end":614},"obj":"Chemical"},{"id":"48","span":{"begin":103,"end":112},"obj":"Disease"},{"id":"49","span":{"begin":356,"end":365},"obj":"Disease"}],"attributes":[{"id":"A37","pred":"tao:has_database_id","subj":"37","obj":"Gene:43740568"},{"id":"A38","pred":"tao:has_database_id","subj":"38","obj":"Gene:43740568"},{"id":"A39","pred":"tao:has_database_id","subj":"39","obj":"Gene:59272"},{"id":"A40","pred":"tao:has_database_id","subj":"40","obj":"Gene:43740570"},{"id":"A41","pred":"tao:has_database_id","subj":"41","obj":"Gene:43740570"},{"id":"A42","pred":"tao:has_database_id","subj":"42","obj":"Gene:43740568"},{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"Tax:694002"},{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"Tax:2697049"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"Tax:2697049"},{"id":"A46","pred":"tao:has_database_id","subj":"46","obj":"Tax:9606"},{"id":"A47","pred":"tao:has_database_id","subj":"47","obj":"MESH:D008051"},{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"MESH:D011014"},{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"MESH:D011014"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"By the end of the year, 2019, Chinese local health authorities reported the occurrence of a cluster of pneumonia cases in Wuhan in the Hubei Province [1]. Shortly after, a novel beta coronavirus—which is now designated as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2]—was discovered in the bronchoalveolar lavage fluid of a patient with pneumonia [1,3]. This enveloped virus has a single-stranded positive sense ribonucleic acid (RNA) genome of approximately 30 kilobases. Several surface proteins, known as the spike (S), envelope (E), and membrane (M) proteins, are embedded in a lipid bilayer. These proteins mediate the viral entry (S; S1 unit: binding to host receptor angiotensin-converting enzyme 2 via its receptor binding domain (RBD) and S2 unit: membrane fusion) and are also responsible for viral fusion (M), morphogenesis (E), assembly (E and M), and budding (M). The RNA is associated with the nucleocapsid (N) protein. The latter plays a role in the viral replication and transcription cycle [4,5,6,7]."}