PMC:7640975 / 62551-63431
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T509 | 71-78 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T510 | 114-119 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T511 | 246-254 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T512 | 276-284 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T513 | 328-333 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T514 | 500-516 | Body_part | denotes | digestive system | http://purl.org/sig/ont/fma/fma7152 |
| T515 | 518-531 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
| T516 | 610-614 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T517 | 874-879 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T42 | 500-516 | Body_part | denotes | digestive system | http://purl.obolibrary.org/obo/UBERON_0001007 |
| T43 | 518-531 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T696 | 114-119 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T697 | 126-127 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T698 | 191-193 | http://purl.obolibrary.org/obo/CL_0000453 | denotes | LC |
| T699 | 194-196 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T700 | 197-199 | http://purl.obolibrary.org/obo/CLO_0007874 | denotes | MS |
| T701 | 201-202 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T702 | 328-333 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T703 | 391-392 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T704 | 472-481 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T705 | 500-516 | http://purl.obolibrary.org/obo/UBERON_0001007 | denotes | digestive system |
| T706 | 500-516 | http://www.ebi.ac.uk/efo/EFO_0000793 | denotes | digestive system |
| T707 | 518-531 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
| T708 | 533-539 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signal |
| T709 | 610-614 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T710 | 621-630 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
| T711 | 874-879 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T18811 | 71-78 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T55089 | 191-193 | Chemical | denotes | LC | http://purl.obolibrary.org/obo/CHEBI_73582 |
| T81472 | 194-196 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T38162 | 197-199 | Chemical | denotes | MS | http://purl.obolibrary.org/obo/CHEBI_73613 |
| T21097 | 246-254 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T1741 | 276-284 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T397 | 472-490 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathways |
| T398 | 472-481 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
| T399 | 533-552 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signal transduction |
| T400 | 540-552 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | transduction |
| T401 | 585-589 | http://purl.obolibrary.org/obo/GO_0016303 | denotes | PI3K |
| T402 | 595-604 | http://purl.obolibrary.org/obo/GO_0016236 | denotes | autophagy |
| T403 | 595-604 | http://purl.obolibrary.org/obo/GO_0006914 | denotes | autophagy |
| T404 | 610-620 | http://purl.obolibrary.org/obo/GO_0007049 | denotes | cell cycle |
| T405 | 621-639 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signaling pathways |
| T406 | 621-630 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T351 | 0-200 | Sentence | denotes | The present study provides the first systematic analysis of the global protein profiles of PDCoV-infected IPEC-J2 cells using a quantitative proteomics approach in which iTRAQ was coupled to LC-MS/MS. |
| T352 | 201-344 | Sentence | denotes | A total of 78 DEPs, including 23 upregulated proteins and 55 downregulated proteins, were identified in PDCoV-infected IPEC-J2 cells at 24 hpi. |
| T353 | 345-640 | Sentence | denotes | Bioinformatics analyses further revealed that a majority of the DEPs were involved in various crucial biological processes and signaling pathways, such as digestive system, immune system, signal transduction, and RIG-I-like receptor, mTOR, PI3K-AKT, autophagy, and cell cycle signaling pathways. |
| T354 | 641-880 | Sentence | denotes | Although further investigations are required to elucidate the functions of the DEPs of interest, our current data provide valuable clues for the in-depth investigation of pathogenic mechanisms of PDCoV and defense mechanisms of host cells. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1250 | 579-583 | Gene | denotes | mTOR | Gene:2475 |
| 1251 | 590-593 | Gene | denotes | AKT | Gene:207 |
| 1252 | 91-105 | Disease | denotes | PDCoV-infected | MESH:D007239 |
| 1253 | 305-319 | Disease | denotes | PDCoV-infected | MESH:D007239 |
| 1254 | 106-113 | CellLine | denotes | IPEC-J2 | CVCL:2246 |
| 1255 | 320-327 | CellLine | denotes | IPEC-J2 | CVCL:2246 |