PMC:7605643 / 26816-27450 JSONTXT

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T39","span":{"begin":445,"end":470},"obj":"Body_part"}],"attributes":[{"id":"A39","pred":"uberon_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"}],"text":"11402337 Nigellicine HDAC1, EP300, AR, PPP1CA, CSNK2A1, RPA1, MAPK1, HDAC6, HSPA1A, CSNK2A2, MAP2K1, MCL1, TP53, NR4A1, ICAM1, TERT, EPRS, SORT1, FEN1, PGR Neuroactive ligand-receptor interaction, cAMP signaling pathway, Nitrogen metabolism, Apoptosis, Lysosome, TNF signaling pathway, NF-Κbsignaling pathway, Influenza A, Autophagy, Alcoholism, Rheumatoid arthritis, HIF-1 signaling pathway, IL-17 signaling pathway, VEGF signaling pathway, Renin- angiotensin system, FOXO signaling pathway, Transcriptional misregulation in cancer, c-GMP PkGsignaling pathway, Oxytocin signaling pathway, Viral carcinogenesis, Nitrogen metabolism"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T140","span":{"begin":256,"end":264},"obj":"Body_part"},{"id":"T141","span":{"begin":565,"end":573},"obj":"Body_part"}],"attributes":[{"id":"A140","pred":"fma_id","subj":"T140","obj":"http://purl.org/sig/ont/fma/fma63836"},{"id":"A141","pred":"fma_id","subj":"T141","obj":"http://purl.org/sig/ont/fma/fma74647"}],"text":"11402337 Nigellicine HDAC1, EP300, AR, PPP1CA, CSNK2A1, RPA1, MAPK1, HDAC6, HSPA1A, CSNK2A2, MAP2K1, MCL1, TP53, NR4A1, ICAM1, TERT, EPRS, SORT1, FEN1, PGR Neuroactive ligand-receptor interaction, cAMP signaling pathway, Nitrogen metabolism, Apoptosis, Lysosome, TNF signaling pathway, NF-Κbsignaling pathway, Influenza A, Autophagy, Alcoholism, Rheumatoid arthritis, HIF-1 signaling pathway, IL-17 signaling pathway, VEGF signaling pathway, Renin- angiotensin system, FOXO signaling pathway, Transcriptional misregulation in cancer, c-GMP PkGsignaling pathway, Oxytocin signaling pathway, Viral carcinogenesis, Nitrogen metabolism"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T83","span":{"begin":313,"end":322},"obj":"Disease"},{"id":"T84","span":{"begin":337,"end":347},"obj":"Disease"},{"id":"T86","span":{"begin":349,"end":369},"obj":"Disease"},{"id":"T87","span":{"begin":360,"end":369},"obj":"Disease"},{"id":"T88","span":{"begin":529,"end":535},"obj":"Disease"}],"attributes":[{"id":"A83","pred":"mondo_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A84","pred":"mondo_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/MONDO_0002046"},{"id":"A85","pred":"mondo_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/MONDO_0007079"},{"id":"A86","pred":"mondo_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/MONDO_0008383"},{"id":"A87","pred":"mondo_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/MONDO_0005578"},{"id":"A88","pred":"mondo_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/MONDO_0004992"}],"text":"11402337 Nigellicine HDAC1, EP300, AR, PPP1CA, CSNK2A1, RPA1, MAPK1, HDAC6, HSPA1A, CSNK2A2, MAP2K1, MCL1, TP53, NR4A1, ICAM1, TERT, EPRS, SORT1, FEN1, PGR Neuroactive ligand-receptor interaction, cAMP signaling pathway, Nitrogen metabolism, Apoptosis, Lysosome, TNF signaling pathway, NF-Κbsignaling pathway, Influenza A, Autophagy, Alcoholism, Rheumatoid arthritis, HIF-1 signaling pathway, IL-17 signaling pathway, VEGF signaling pathway, Renin- angiotensin system, FOXO signaling pathway, Transcriptional misregulation in cancer, c-GMP PkGsignaling pathway, Oxytocin signaling pathway, Viral carcinogenesis, Nitrogen metabolism"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T315","span":{"begin":154,"end":157},"obj":"http://purl.obolibrary.org/obo/PR_000012621"},{"id":"T316","span":{"begin":200,"end":204},"obj":"http://purl.obolibrary.org/obo/CLO_0053428"},{"id":"T317","span":{"begin":205,"end":214},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T318","span":{"begin":256,"end":264},"obj":"http://purl.obolibrary.org/obo/GO_0005764"},{"id":"T319","span":{"begin":270,"end":279},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T320","span":{"begin":323,"end":324},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T321","span":{"begin":377,"end":386},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T322","span":{"begin":402,"end":411},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T323","span":{"begin":426,"end":435},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T324","span":{"begin":477,"end":486},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T325","span":{"begin":574,"end":583},"obj":"http://purl.obolibrary.org/obo/SO_0000418"}],"text":"11402337 Nigellicine HDAC1, EP300, AR, PPP1CA, CSNK2A1, RPA1, MAPK1, HDAC6, HSPA1A, CSNK2A2, MAP2K1, MCL1, TP53, NR4A1, ICAM1, TERT, EPRS, SORT1, FEN1, PGR Neuroactive ligand-receptor interaction, cAMP signaling pathway, Nitrogen metabolism, Apoptosis, Lysosome, TNF signaling pathway, NF-Κbsignaling pathway, Influenza A, Autophagy, Alcoholism, Rheumatoid arthritis, HIF-1 signaling pathway, IL-17 signaling pathway, VEGF signaling pathway, Renin- angiotensin system, FOXO signaling pathway, Transcriptional misregulation in cancer, c-GMP PkGsignaling pathway, Oxytocin signaling pathway, Viral carcinogenesis, Nitrogen metabolism"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T273","span":{"begin":37,"end":39},"obj":"Chemical"},{"id":"T274","span":{"begin":171,"end":177},"obj":"Chemical"},{"id":"T275","span":{"begin":200,"end":204},"obj":"Chemical"},{"id":"T276","span":{"begin":224,"end":232},"obj":"Chemical"},{"id":"T277","span":{"begin":289,"end":291},"obj":"Chemical"},{"id":"T280","span":{"begin":396,"end":398},"obj":"Chemical"},{"id":"T282","span":{"begin":452,"end":463},"obj":"Chemical"},{"id":"T283","span":{"begin":539,"end":542},"obj":"Chemical"},{"id":"T285","span":{"begin":565,"end":573},"obj":"Chemical"},{"id":"T286","span":{"begin":615,"end":623},"obj":"Chemical"}],"attributes":[{"id":"A273","pred":"chebi_id","subj":"T273","obj":"http://purl.obolibrary.org/obo/CHEBI_137238"},{"id":"A274","pred":"chebi_id","subj":"T274","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A275","pred":"chebi_id","subj":"T275","obj":"http://purl.obolibrary.org/obo/CHEBI_17489"},{"id":"A276","pred":"chebi_id","subj":"T276","obj":"http://purl.obolibrary.org/obo/CHEBI_17997"},{"id":"A277","pred":"chebi_id","subj":"T277","obj":"http://purl.obolibrary.org/obo/CHEBI_141424"},{"id":"A278","pred":"chebi_id","subj":"T277","obj":"http://purl.obolibrary.org/obo/CHEBI_25573"},{"id":"A279","pred":"chebi_id","subj":"T277","obj":"http://purl.obolibrary.org/obo/CHEBI_1224"},{"id":"A280","pred":"chebi_id","subj":"T280","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A281","pred":"chebi_id","subj":"T280","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A282","pred":"chebi_id","subj":"T282","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A283","pred":"chebi_id","subj":"T283","obj":"http://purl.obolibrary.org/obo/CHEBI_17345"},{"id":"A284","pred":"chebi_id","subj":"T283","obj":"http://purl.obolibrary.org/obo/CHEBI_58115"},{"id":"A285","pred":"chebi_id","subj":"T285","obj":"http://purl.obolibrary.org/obo/CHEBI_7872"},{"id":"A286","pred":"chebi_id","subj":"T286","obj":"http://purl.obolibrary.org/obo/CHEBI_17997"}],"text":"11402337 Nigellicine HDAC1, EP300, AR, PPP1CA, CSNK2A1, RPA1, MAPK1, HDAC6, HSPA1A, CSNK2A2, MAP2K1, MCL1, TP53, NR4A1, ICAM1, TERT, EPRS, SORT1, FEN1, PGR Neuroactive ligand-receptor interaction, cAMP signaling pathway, Nitrogen metabolism, Apoptosis, Lysosome, TNF signaling pathway, NF-Κbsignaling pathway, Influenza A, Autophagy, Alcoholism, Rheumatoid arthritis, HIF-1 signaling pathway, IL-17 signaling pathway, VEGF signaling pathway, Renin- angiotensin system, FOXO signaling pathway, Transcriptional misregulation in cancer, c-GMP PkGsignaling pathway, Oxytocin signaling pathway, Viral carcinogenesis, Nitrogen metabolism"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T414","span":{"begin":200,"end":214},"obj":"http://purl.obolibrary.org/obo/GO_0019933"},{"id":"T415","span":{"begin":205,"end":214},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T416","span":{"begin":233,"end":243},"obj":"http://purl.obolibrary.org/obo/GO_0008152"},{"id":"T417","span":{"begin":245,"end":254},"obj":"http://purl.obolibrary.org/obo/GO_0097194"},{"id":"T418","span":{"begin":245,"end":254},"obj":"http://purl.obolibrary.org/obo/GO_0006915"},{"id":"T419","span":{"begin":270,"end":287},"obj":"http://purl.obolibrary.org/obo/GO_0007165"},{"id":"T420","span":{"begin":270,"end":279},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T421","span":{"begin":326,"end":335},"obj":"http://purl.obolibrary.org/obo/GO_0016236"},{"id":"T422","span":{"begin":326,"end":335},"obj":"http://purl.obolibrary.org/obo/GO_0006914"},{"id":"T423","span":{"begin":377,"end":394},"obj":"http://purl.obolibrary.org/obo/GO_0007165"},{"id":"T424","span":{"begin":377,"end":386},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T425","span":{"begin":402,"end":419},"obj":"http://purl.obolibrary.org/obo/GO_0007165"},{"id":"T426","span":{"begin":402,"end":411},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T427","span":{"begin":421,"end":435},"obj":"http://purl.obolibrary.org/obo/GO_0038084"},{"id":"T428","span":{"begin":426,"end":435},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T429","span":{"begin":477,"end":494},"obj":"http://purl.obolibrary.org/obo/GO_0007165"},{"id":"T430","span":{"begin":477,"end":486},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T431","span":{"begin":496,"end":511},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T432","span":{"begin":574,"end":591},"obj":"http://purl.obolibrary.org/obo/GO_0007165"},{"id":"T433","span":{"begin":574,"end":583},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T434","span":{"begin":624,"end":634},"obj":"http://purl.obolibrary.org/obo/GO_0008152"}],"text":"11402337 Nigellicine HDAC1, EP300, AR, PPP1CA, CSNK2A1, RPA1, MAPK1, HDAC6, HSPA1A, CSNK2A2, MAP2K1, MCL1, TP53, NR4A1, ICAM1, TERT, EPRS, SORT1, FEN1, PGR Neuroactive ligand-receptor interaction, cAMP signaling pathway, Nitrogen metabolism, Apoptosis, Lysosome, TNF signaling pathway, NF-Κbsignaling pathway, Influenza A, Autophagy, Alcoholism, Rheumatoid arthritis, HIF-1 signaling pathway, IL-17 signaling pathway, VEGF signaling pathway, Renin- angiotensin system, FOXO signaling pathway, Transcriptional misregulation in cancer, c-GMP PkGsignaling pathway, Oxytocin signaling pathway, Viral carcinogenesis, Nitrogen metabolism"}

{"project":"LitCovid-sentences","denotations":[{"id":"T150","span":{"begin":0,"end":634},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"11402337 Nigellicine HDAC1, EP300, AR, PPP1CA, CSNK2A1, RPA1, MAPK1, HDAC6, HSPA1A, CSNK2A2, MAP2K1, MCL1, TP53, NR4A1, ICAM1, TERT, EPRS, SORT1, FEN1, PGR Neuroactive ligand-receptor interaction, cAMP signaling pathway, Nitrogen metabolism, Apoptosis, Lysosome, TNF signaling pathway, NF-Κbsignaling pathway, Influenza A, Autophagy, Alcoholism, Rheumatoid arthritis, HIF-1 signaling pathway, IL-17 signaling pathway, VEGF signaling pathway, Renin- angiotensin system, FOXO signaling pathway, Transcriptional misregulation in cancer, c-GMP PkGsignaling pathway, Oxytocin signaling pathway, Viral carcinogenesis, Nitrogen metabolism"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T31","span":{"begin":337,"end":347},"obj":"Phenotype"},{"id":"T32","span":{"begin":349,"end":369},"obj":"Phenotype"},{"id":"T33","span":{"begin":529,"end":535},"obj":"Phenotype"}],"attributes":[{"id":"A31","pred":"hp_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/HP_0030955"},{"id":"A32","pred":"hp_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/HP_0001370"},{"id":"A33","pred":"hp_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/HP_0002664"}],"text":"11402337 Nigellicine HDAC1, EP300, AR, PPP1CA, CSNK2A1, RPA1, MAPK1, HDAC6, HSPA1A, CSNK2A2, MAP2K1, MCL1, TP53, NR4A1, ICAM1, TERT, EPRS, SORT1, FEN1, PGR Neuroactive ligand-receptor interaction, cAMP signaling pathway, Nitrogen metabolism, Apoptosis, Lysosome, TNF signaling pathway, NF-Κbsignaling pathway, Influenza A, Autophagy, Alcoholism, Rheumatoid arthritis, HIF-1 signaling pathway, IL-17 signaling pathway, VEGF signaling pathway, Renin- angiotensin system, FOXO signaling pathway, Transcriptional misregulation in cancer, c-GMP PkGsignaling pathway, Oxytocin signaling pathway, Viral carcinogenesis, Nitrogen metabolism"}

{"project":"LitCovid-PubTator","denotations":[{"id":"530","span":{"begin":421,"end":425},"obj":"Gene"},{"id":"531","span":{"begin":445,"end":450},"obj":"Gene"},{"id":"537","span":{"begin":224,"end":232},"obj":"Chemical"},{"id":"538","span":{"begin":615,"end":623},"obj":"Chemical"},{"id":"583","span":{"begin":289,"end":303},"obj":"Disease"},{"id":"584","span":{"begin":337,"end":347},"obj":"Disease"},{"id":"585","span":{"begin":349,"end":369},"obj":"Disease"},{"id":"586","span":{"begin":529,"end":535},"obj":"Disease"},{"id":"587","span":{"begin":543,"end":555},"obj":"Disease"},{"id":"588","span":{"begin":593,"end":613},"obj":"Disease"},{"id":"597","span":{"begin":129,"end":133},"obj":"CellLine"}],"attributes":[{"id":"A530","pred":"tao:has_database_id","subj":"530","obj":"Gene:83785"},{"id":"A531","pred":"tao:has_database_id","subj":"531","obj":"Gene:5972"},{"id":"A537","pred":"tao:has_database_id","subj":"537","obj":"MESH:D009584"},{"id":"A538","pred":"tao:has_database_id","subj":"538","obj":"MESH:D009584"},{"id":"A583","pred":"tao:has_database_id","subj":"583","obj":"MESH:C537392"},{"id":"A584","pred":"tao:has_database_id","subj":"584","obj":"MESH:D000437"},{"id":"A585","pred":"tao:has_database_id","subj":"585","obj":"MESH:D001172"},{"id":"A586","pred":"tao:has_database_id","subj":"586","obj":"MESH:D009369"},{"id":"A597","pred":"tao:has_database_id","subj":"597","obj":"CVCL:C452"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"11402337 Nigellicine HDAC1, EP300, AR, PPP1CA, CSNK2A1, RPA1, MAPK1, HDAC6, HSPA1A, CSNK2A2, MAP2K1, MCL1, TP53, NR4A1, ICAM1, TERT, EPRS, SORT1, FEN1, PGR Neuroactive ligand-receptor interaction, cAMP signaling pathway, Nitrogen metabolism, Apoptosis, Lysosome, TNF signaling pathway, NF-Κbsignaling pathway, Influenza A, Autophagy, Alcoholism, Rheumatoid arthritis, HIF-1 signaling pathway, IL-17 signaling pathway, VEGF signaling pathway, Renin- angiotensin system, FOXO signaling pathway, Transcriptional misregulation in cancer, c-GMP PkGsignaling pathway, Oxytocin signaling pathway, Viral carcinogenesis, Nitrogen metabolism"}