PMC:7605337 / 44194-45012
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T301 | 128-137 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T302 | 244-248 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T303 | 335-344 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T304 | 398-407 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T305 | 413-417 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T306 | 709-718 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T277 | 145-146 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T301 | 0-210 | Sentence | denotes | To better characterize the functional motions of RBD, DCCM for all systems are constructed and shown in Figure 6 and Figure S6. nCOV-2019 showed a large correlation between the α4-L1- β5 and α5- L4- β5 regions. |
| T302 | 211-301 | Sentence | denotes | This correlation was stronger in SARS-COV and few mutants such as Y449A, G447A, and E484A. |
| T303 | 302-365 | Sentence | denotes | Another important correlation in nCOV-2019 is inside L3 and β6. |
| T304 | 366-497 | Sentence | denotes | This correlation is stronger in nCOV-2019 than SARS-COV due to the presence of β6 which makes the loop to adopt correlated motions. |
| T305 | 498-562 | Sentence | denotes | Few mutants impact the correlation in this region such as N487A. |
| T306 | 563-818 | Sentence | denotes | Interestingly, mutant F486A which is in L3 and participates in binding by π-stacking interaction with Y83 on ACE2, disrupts the DCCM of wild-type nCOV-2019 and introduces strong correlation in the extended loop region as well as the core structure of RBD. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1088 | 362-364 | Gene | denotes | β6 | Gene:28873 |
| 1089 | 672-676 | Gene | denotes | ACE2 | Gene:59272 |
| 1090 | 445-447 | Gene | denotes | β6 | Gene:28873 |
| 1091 | 199-201 | Gene | denotes | β5 | Gene:28884 |
| 1092 | 191-193 | Gene | denotes | α5 | Gene:28884 |
| 1093 | 184-186 | Gene | denotes | β5 | Gene:28884 |
| 1094 | 177-179 | Gene | denotes | α4 | Gene:28898 |
| 1095 | 128-132 | Species | denotes | nCOV | Tax:2697049 |
| 1096 | 244-252 | Species | denotes | SARS-COV | Tax:694009 |
| 1097 | 335-339 | Species | denotes | nCOV | Tax:2697049 |
| 1098 | 398-402 | Species | denotes | nCOV | Tax:2697049 |
| 1099 | 413-421 | Species | denotes | SARS-COV | Tax:694009 |
| 1100 | 709-713 | Species | denotes | nCOV | Tax:2697049 |
| 1101 | 54-58 | Chemical | denotes | DCCM |