PMC:7605337 / 11785-12453
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T39 | 62-69 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T40 | 241-248 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T88 | 0-9 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T89 | 46-50 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T90 | 182-191 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T91 | 277-281 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T92 | 317-321 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T93 | 407-416 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T94 | 546-555 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T95 | 622-631 | Disease | denotes | nCOV-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T45 | 62-69 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T46 | 241-248 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T61 | 0-668 | Sentence | denotes | nCOV-2019 shares 76% sequence similarity with SARS-2002 spike protein, 73% sequence identity for RBD and 50% for the RBM.1 Bat coronavirus RaTG13 seems to be the closest relative of nCOV-2019 sharing about 93% sequence identity in the spike protein.6 The sequence alignment of SARS-2002 (accession number: AFR58742), SARS-civet (accession number: AY304486.1), Bat RaTG13 (accession number: MN996532.1), and nCOV-2019 (accession number: MN908947.1) is shown in Figure 2.6 To investigate the roles of critical mutations on the complex stability of nCOV-2019 with ACE2, mCSM-PPI2 webserver32 was used to find the residues in nCOV-2019 that are at the interface with ACE2. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
333 | 235-240 | Gene | denotes | spike | Gene:43740568 |
334 | 561-565 | Gene | denotes | ACE2 | Gene:59272 |
335 | 663-667 | Gene | denotes | ACE2 | Gene:59272 |
337 | 56-61 | Gene | denotes | spike | Gene:43740568 |
338 | 0-4 | Species | denotes | nCOV | Tax:2697049 |
339 | 123-145 | Species | denotes | Bat coronavirus RaTG13 | Tax:2709072 |
340 | 182-186 | Species | denotes | nCOV | Tax:2697049 |
341 | 407-411 | Species | denotes | nCOV | Tax:2697049 |
342 | 546-550 | Species | denotes | nCOV | Tax:2697049 |
343 | 622-626 | Species | denotes | nCOV | Tax:2697049 |
346 | 390-400 | CellLine | denotes | MN996532.1 | CVCL:U508 |
347 | 436-446 | CellLine | denotes | MN908947.1 | CVCL:U508 |