PMC:7601109 / 46567-46990
Annnotations
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T71 | 396-410 | Body_part | denotes | adipose tissue | http://purl.obolibrary.org/obo/UBERON_0001013 |
| T72 | 404-410 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T326 | 53-60 | Body_part | denotes | insulin | http://purl.org/sig/ont/fma/fma83365 |
| T327 | 148-155 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T328 | 263-270 | Body_part | denotes | insulin | http://purl.org/sig/ont/fma/fma83365 |
| T329 | 282-289 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
| T330 | 323-330 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
| T331 | 343-348 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T332 | 360-367 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
| T333 | 385-391 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
| T334 | 396-410 | Body_part | denotes | adipose tissue | http://purl.org/sig/ont/fma/fma20110 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T658 | 35-45 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T659 | 53-69 | http://purl.obolibrary.org/obo/PR_000009064 | denotes | insulin receptor |
| T660 | 71-73 | http://purl.obolibrary.org/obo/PR_000009064 | denotes | IR |
| T661 | 126-136 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T662 | 217-227 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
| T663 | 263-270 | http://purl.obolibrary.org/obo/PR_000009054 | denotes | insulin |
| T664 | 343-348 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T665 | 376-391 | http://purl.obolibrary.org/obo/UBERON_0001134 | denotes | skeletal muscle |
| T666 | 376-391 | http://purl.obolibrary.org/obo/UBERON_0014892 | denotes | skeletal muscle |
| T667 | 376-391 | http://www.ebi.ac.uk/efo/EFO_0000888 | denotes | skeletal muscle |
| T668 | 396-410 | http://purl.obolibrary.org/obo/UBERON_0001013 | denotes | adipose tissue |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T698 | 53-60 | Chemical | denotes | insulin | http://purl.obolibrary.org/obo/CHEBI_145810 |
| T699 | 71-73 | Chemical | denotes | IR | http://purl.obolibrary.org/obo/CHEBI_74061 |
| T700 | 148-155 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T701 | 239-248 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T702 | 263-270 | Chemical | denotes | insulin | http://purl.obolibrary.org/obo/CHEBI_145810 |
| T703 | 282-289 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
| T705 | 323-330 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T185 | 0-15 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | Phosphorylation |
| T186 | 19-23 | http://purl.obolibrary.org/obo/GO_0050405 | denotes | AMPK |
| T187 | 19-23 | http://purl.obolibrary.org/obo/GO_0047322 | denotes | AMPK |
| T188 | 19-23 | http://purl.obolibrary.org/obo/GO_0004691 | denotes | AMPK |
| T189 | 90-105 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
| T190 | 109-113 | http://purl.obolibrary.org/obo/GO_0016303 | denotes | PI3K |
| T191 | 163-170 | http://purl.obolibrary.org/obo/GO_0004697 | denotes | C (PKC) |
| T192 | 282-299 | http://purl.obolibrary.org/obo/GO_1904659 | denotes | glucose transport |
| T193 | 290-299 | http://purl.obolibrary.org/obo/GO_0006810 | denotes | transport |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T284 | 0-423 | Sentence | denotes | Phosphorylation of AMPK results in activation of the insulin receptor (IR) and subsequent phosphorylation of PI3K followed by activation of AKT and protein kinase C (PKC) leading to GLUT4 translocation and subsequent activation of several molecules that modulate insulin-stimulated glucose transport, eventually leading to glucose influx into cells of several tissues such as skeletal muscle and adipose tissue [69,70,111]. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1101 | 19-23 | Gene | denotes | AMPK | Gene:78975 |
| 1102 | 53-69 | Gene | denotes | insulin receptor | Gene:24954 |
| 1103 | 140-143 | Gene | denotes | AKT | Gene:24185 |
| 1104 | 182-187 | Gene | denotes | GLUT4 | Gene:25139 |
| 1105 | 263-270 | Gene | denotes | insulin | Gene:3630 |
| 1116 | 282-289 | Chemical | denotes | glucose | MESH:D005947 |
| 1117 | 323-330 | Chemical | denotes | glucose | MESH:D005947 |