PMC:7601109 / 19563-20415
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7601109","sourcedb":"PMC","sourceid":"7601109","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7601109","text":"Propolis is not suitable for use in its crude state since it may contact harmful materials e.g., asphalt from the road [68]. Using solvents like ethanol, glycerol, chloroform, ether and acetone or water is necessary to get rid of hazardous substances and to increase its yield of bioactive compounds [67,68]. Although water may be a cheap solvent, propolis has poor solubility in water. Therefore, propolis water extracts are 10-fold lower in their phenolic contents than ethanol extracts. In addition, they retain the strong flavor and aroma of propolis [68]. Moreover, propolis contains allergenic components: caffeic acids derivates (e.g., 3-methyl-2-butenyl caffeate and phenylethyl caffeate), as well as benzyl salicylate and benzyl cinnamate [80]. Therefore, propolis use/consumption should be contraindicated in individuals with known allergies.","tracks":[{"project":"LitCovid-PD-CLO","denotations":[{"id":"T98959","span":{"begin":331,"end":332},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T49007","span":{"begin":357,"end":360},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"attributes":[{"subj":"T98959","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T49007","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T307","span":{"begin":131,"end":139},"obj":"Chemical"},{"id":"T308","span":{"begin":145,"end":152},"obj":"Chemical"},{"id":"T309","span":{"begin":154,"end":162},"obj":"Chemical"},{"id":"T310","span":{"begin":164,"end":174},"obj":"Chemical"},{"id":"T311","span":{"begin":176,"end":181},"obj":"Chemical"},{"id":"T312","span":{"begin":186,"end":193},"obj":"Chemical"},{"id":"T313","span":{"begin":197,"end":202},"obj":"Chemical"},{"id":"T314","span":{"begin":318,"end":323},"obj":"Chemical"},{"id":"T315","span":{"begin":339,"end":346},"obj":"Chemical"},{"id":"T316","span":{"begin":380,"end":385},"obj":"Chemical"},{"id":"T317","span":{"begin":407,"end":412},"obj":"Chemical"},{"id":"T318","span":{"begin":472,"end":479},"obj":"Chemical"},{"id":"T319","span":{"begin":537,"end":542},"obj":"Chemical"},{"id":"T320","span":{"begin":620,"end":625},"obj":"Chemical"},{"id":"T321","span":{"begin":645,"end":651},"obj":"Chemical"},{"id":"T323","span":{"begin":709,"end":715},"obj":"Chemical"},{"id":"T324","span":{"begin":716,"end":726},"obj":"Chemical"},{"id":"T325","span":{"begin":731,"end":747},"obj":"Chemical"},{"id":"T326","span":{"begin":731,"end":737},"obj":"Chemical"},{"id":"T327","span":{"begin":738,"end":747},"obj":"Chemical"}],"attributes":[{"id":"A307","pred":"chebi_id","subj":"T307","obj":"http://purl.obolibrary.org/obo/CHEBI_46787"},{"id":"A308","pred":"chebi_id","subj":"T308","obj":"http://purl.obolibrary.org/obo/CHEBI_16236"},{"id":"A309","pred":"chebi_id","subj":"T309","obj":"http://purl.obolibrary.org/obo/CHEBI_17754"},{"id":"A310","pred":"chebi_id","subj":"T310","obj":"http://purl.obolibrary.org/obo/CHEBI_35255"},{"id":"A311","pred":"chebi_id","subj":"T311","obj":"http://purl.obolibrary.org/obo/CHEBI_25698"},{"id":"A312","pred":"chebi_id","subj":"T312","obj":"http://purl.obolibrary.org/obo/CHEBI_15347"},{"id":"A313","pred":"chebi_id","subj":"T313","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A314","pred":"chebi_id","subj":"T314","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A315","pred":"chebi_id","subj":"T315","obj":"http://purl.obolibrary.org/obo/CHEBI_46787"},{"id":"A316","pred":"chebi_id","subj":"T316","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A317","pred":"chebi_id","subj":"T317","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A318","pred":"chebi_id","subj":"T318","obj":"http://purl.obolibrary.org/obo/CHEBI_16236"},{"id":"A319","pred":"chebi_id","subj":"T319","obj":"http://purl.obolibrary.org/obo/CHEBI_48318"},{"id":"A320","pred":"chebi_id","subj":"T320","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A321","pred":"chebi_id","subj":"T321","obj":"http://purl.obolibrary.org/obo/CHEBI_32875"},{"id":"A322","pred":"chebi_id","subj":"T321","obj":"http://purl.obolibrary.org/obo/CHEBI_29309"},{"id":"A323","pred":"chebi_id","subj":"T323","obj":"http://purl.obolibrary.org/obo/CHEBI_22744"},{"id":"A324","pred":"chebi_id","subj":"T324","obj":"http://purl.obolibrary.org/obo/CHEBI_30762"},{"id":"A325","pred":"chebi_id","subj":"T325","obj":"http://purl.obolibrary.org/obo/CHEBI_146174"},{"id":"A326","pred":"chebi_id","subj":"T326","obj":"http://purl.obolibrary.org/obo/CHEBI_22744"},{"id":"A327","pred":"chebi_id","subj":"T327","obj":"http://purl.obolibrary.org/obo/CHEBI_23248"},{"subj":"T307","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T308","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T309","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T310","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T311","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T312","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T313","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T314","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T315","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T316","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T317","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T318","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T319","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T320","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T321","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T323","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T324","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T325","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T326","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T327","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T122","span":{"begin":0,"end":124},"obj":"Sentence"},{"id":"T123","span":{"begin":125,"end":308},"obj":"Sentence"},{"id":"T124","span":{"begin":309,"end":386},"obj":"Sentence"},{"id":"T125","span":{"begin":387,"end":489},"obj":"Sentence"},{"id":"T126","span":{"begin":490,"end":560},"obj":"Sentence"},{"id":"T127","span":{"begin":561,"end":753},"obj":"Sentence"},{"id":"T128","span":{"begin":754,"end":852},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T122","pred":"source","obj":"LitCovid-sentences"},{"subj":"T123","pred":"source","obj":"LitCovid-sentences"},{"subj":"T124","pred":"source","obj":"LitCovid-sentences"},{"subj":"T125","pred":"source","obj":"LitCovid-sentences"},{"subj":"T126","pred":"source","obj":"LitCovid-sentences"},{"subj":"T127","pred":"source","obj":"LitCovid-sentences"},{"subj":"T128","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"345","span":{"begin":145,"end":152},"obj":"Chemical"},{"id":"346","span":{"begin":154,"end":162},"obj":"Chemical"},{"id":"347","span":{"begin":164,"end":174},"obj":"Chemical"},{"id":"348","span":{"begin":176,"end":181},"obj":"Chemical"},{"id":"349","span":{"begin":186,"end":193},"obj":"Chemical"},{"id":"350","span":{"begin":197,"end":202},"obj":"Chemical"},{"id":"351","span":{"begin":318,"end":323},"obj":"Chemical"},{"id":"352","span":{"begin":380,"end":385},"obj":"Chemical"},{"id":"353","span":{"begin":407,"end":412},"obj":"Chemical"},{"id":"354","span":{"begin":472,"end":479},"obj":"Chemical"},{"id":"355","span":{"begin":612,"end":625},"obj":"Chemical"},{"id":"356","span":{"begin":643,"end":670},"obj":"Chemical"},{"id":"357","span":{"begin":675,"end":695},"obj":"Chemical"},{"id":"358","span":{"begin":709,"end":726},"obj":"Chemical"},{"id":"359","span":{"begin":731,"end":747},"obj":"Chemical"}],"attributes":[{"id":"A345","pred":"tao:has_database_id","subj":"345","obj":"MESH:D000431"},{"id":"A346","pred":"tao:has_database_id","subj":"346","obj":"MESH:D005990"},{"id":"A347","pred":"tao:has_database_id","subj":"347","obj":"MESH:D002725"},{"id":"A348","pred":"tao:has_database_id","subj":"348","obj":"MESH:D004986"},{"id":"A349","pred":"tao:has_database_id","subj":"349","obj":"MESH:D000096"},{"id":"A350","pred":"tao:has_database_id","subj":"350","obj":"MESH:D014867"},{"id":"A351","pred":"tao:has_database_id","subj":"351","obj":"MESH:D014867"},{"id":"A352","pred":"tao:has_database_id","subj":"352","obj":"MESH:D014867"},{"id":"A353","pred":"tao:has_database_id","subj":"353","obj":"MESH:D014867"},{"id":"A354","pred":"tao:has_database_id","subj":"354","obj":"MESH:D000431"},{"id":"A355","pred":"tao:has_database_id","subj":"355","obj":"MESH:D002109"},{"id":"A356","pred":"tao:has_database_id","subj":"356","obj":"MESH:C054126"},{"id":"A358","pred":"tao:has_database_id","subj":"358","obj":"MESH:C039672"},{"id":"A359","pred":"tao:has_database_id","subj":"359","obj":"MESH:C526327"},{"subj":"345","pred":"source","obj":"LitCovid-PubTator"},{"subj":"346","pred":"source","obj":"LitCovid-PubTator"},{"subj":"347","pred":"source","obj":"LitCovid-PubTator"},{"subj":"348","pred":"source","obj":"LitCovid-PubTator"},{"subj":"349","pred":"source","obj":"LitCovid-PubTator"},{"subj":"350","pred":"source","obj":"LitCovid-PubTator"},{"subj":"351","pred":"source","obj":"LitCovid-PubTator"},{"subj":"352","pred":"source","obj":"LitCovid-PubTator"},{"subj":"353","pred":"source","obj":"LitCovid-PubTator"},{"subj":"354","pred":"source","obj":"LitCovid-PubTator"},{"subj":"355","pred":"source","obj":"LitCovid-PubTator"},{"subj":"356","pred":"source","obj":"LitCovid-PubTator"},{"subj":"357","pred":"source","obj":"LitCovid-PubTator"},{"subj":"358","pred":"source","obj":"LitCovid-PubTator"},{"subj":"359","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-CLO","color":"#9399ec","default":true},{"id":"LitCovid-PD-CHEBI","color":"#b3ec93"},{"id":"LitCovid-sentences","color":"#ec93cd"},{"id":"LitCovid-PubTator","color":"#93e7ec"}]}]}}