PMC:7600245 / 82085-83627
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T368 | 72-76 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T369 | 104-107 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T370 | 228-232 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T371 | 277-290 | Body_part | denotes | cell membrane | http://purl.org/sig/ont/fma/fma63841 |
| T372 | 277-281 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T373 | 292-300 | Body_part | denotes | clathrin | http://purl.org/sig/ont/fma/fma62262 |
| T374 | 352-358 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T375 | 373-384 | Body_part | denotes | cytoplasmic | http://purl.org/sig/ont/fma/fma66835 |
| T376 | 411-415 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
| T377 | 437-440 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T378 | 558-561 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T379 | 589-596 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T380 | 778-786 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T381 | 881-888 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T382 | 902-906 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T383 | 1265-1276 | Body_part | denotes | nucleotides | http://purl.org/sig/ont/fma/fma82740 |
| T384 | 1307-1311 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T385 | 1453-1461 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T46 | 72-76 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
| T47 | 411-415 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T399 | 18-26 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T400 | 1008-1023 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T401 | 1014-1023 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T861 | 153-158 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T862 | 210-215 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T863 | 228-232 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T864 | 247-255 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T865 | 277-281 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T866 | 282-290 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T867 | 511-516 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T868 | 663-668 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T869 | 902-906 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T870 | 1087-1088 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T871 | 1106-1111 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T872 | 1151-1152 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T873 | 1196-1201 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T874 | 1307-1311 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T14490 | 589-596 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T30206 | 778-786 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T69806 | 881-888 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T90206 | 1265-1276 | Chemical | denotes | nucleotides | http://purl.obolibrary.org/obo/CHEBI_36976 |
| T28645 | 1350-1357 | Chemical | denotes | inosine | http://purl.obolibrary.org/obo/CHEBI_17596 |
| T37811 | 1390-1404 | Chemical | denotes | dihydroorotate | http://purl.obolibrary.org/obo/CHEBI_30867 |
| T29604 | 1453-1461 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T165 | 104-119 | http://purl.obolibrary.org/obo/GO_0039703 | denotes | RNA replication |
| T166 | 247-262 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
| T167 | 292-321 | http://purl.obolibrary.org/obo/GO_0072583 | denotes | clathrin-mediated endocytosis |
| T168 | 310-321 | http://purl.obolibrary.org/obo/GO_0006897 | denotes | endocytosis |
| T169 | 437-452 | http://purl.obolibrary.org/obo/GO_0039703 | denotes | RNA replication |
| T170 | 558-573 | http://purl.obolibrary.org/obo/GO_0039703 | denotes | RNA replication |
| T171 | 583-606 | http://purl.obolibrary.org/obo/GO_0019081 | denotes | viral protein synthesis |
| T172 | 589-606 | http://purl.obolibrary.org/obo/GO_0006412 | denotes | protein synthesis |
| T173 | 597-606 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
| T174 | 627-650 | http://purl.obolibrary.org/obo/GO_0019068 | denotes | viral particle assembly |
| T175 | 1008-1023 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
| T176 | 1061-1077 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral life cycle |
| T177 | 1106-1129 | http://purl.obolibrary.org/obo/GO_0019048 | denotes | virus–host interactions |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T645 | 0-60 | Sentence | denotes | The life cycle of SARS-CoV-2 can be divided into two phases. |
| T646 | 61-170 | Sentence | denotes | On the one hand, events prior to the viral RNA replication represent the early stage of the virus life cycle. |
| T647 | 171-397 | Sentence | denotes | This stage involves the binding of the virus to the host cell receptor, its membrane fusion with the host cell membrane, clathrin-mediated endocytosis, and the release of the viral genome into the host cytoplasmic environment. |
| T648 | 398-528 | Sentence | denotes | On the other hand, events that involve RNA replication and subsequent processes represent the later stage of the virus life cycle. |
| T649 | 529-677 | Sentence | denotes | Specifically, it entails the RNA replication process, viral protein synthesis and processing, and viral particle assembly, and mature virus release. |
| T650 | 678-787 | Sentence | denotes | Notably, events in the two phases are mediated by several interactions among various viral and host proteins. |
| T651 | 788-921 | Sentence | denotes | For example, the viral entry is initially mediated by interactions between the viral spike S protein and the host cell receptor ACE2. |
| T652 | 922-1024 | Sentence | denotes | Furin, TMPRSS2, and cathepsin L enzymes are also important for the early stage of the viral infection. |
| T653 | 1025-1178 | Sentence | denotes | Importantly, the later stage of the viral life cycle involves a different set of virus–host interactions that are mediated by a different set of enzymes. |
| T654 | 1179-1419 | Sentence | denotes | For example, the virus genetic material replication is catalyzed by RdRp and requires nucleotides that are provided by the host cell and biosynthesized by enzymes such as inosine monophosphate dehydrogenase and dihydroorotate dehydrogenase. |
| T655 | 1420-1542 | Sentence | denotes | Furthermore, the resulting viral proteins require further processing which takes place by the action of by Mpro and PLpro. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 2560 | 916-920 | Gene | denotes | ACE2 | Gene:59272 |
| 2561 | 922-927 | Gene | denotes | Furin | Gene:5045 |
| 2562 | 929-936 | Gene | denotes | TMPRSS2 | Gene:7113 |
| 2563 | 942-953 | Gene | denotes | cathepsin L | Gene:1514 |
| 2564 | 1247-1251 | Gene | denotes | RdRp | Gene:43740578 |
| 2565 | 1390-1418 | Gene | denotes | dihydroorotate dehydrogenase | Gene:1723 |
| 2566 | 1527-1531 | Gene | denotes | Mpro | Gene:8673700 |
| 2567 | 1536-1541 | Gene | denotes | PLpro | Gene:43740578 |
| 2568 | 18-28 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 2569 | 1008-1023 | Disease | denotes | viral infection | MESH:D001102 |