PMC:7600245 / 19544-19868
Annnotations
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T178 | 0-10 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | Activation |
T179 | 177-178 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T180 | 295-301 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
T181 | 315-317 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T240 | 18-22 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T241 | 66-72 | Chemical | denotes | esters | http://purl.obolibrary.org/obo/CHEBI_35701 |
T242 | 108-122 | Chemical | denotes | carbon dioxide | http://purl.obolibrary.org/obo/CHEBI_16526 |
T243 | 108-114 | Chemical | denotes | carbon | http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415 |
T245 | 127-139 | Chemical | denotes | formaldehyde | http://purl.obolibrary.org/obo/CHEBI_16842 |
T246 | 166-175 | Chemical | denotes | tenofovir | http://purl.obolibrary.org/obo/CHEBI_134504|http://purl.obolibrary.org/obo/CHEBI_63625|http://purl.obolibrary.org/obo/CHEBI_63716 |
T249 | 177-189 | Chemical | denotes | a nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
T250 | 268-277 | Chemical | denotes | tenofovir | http://purl.obolibrary.org/obo/CHEBI_134504|http://purl.obolibrary.org/obo/CHEBI_63625|http://purl.obolibrary.org/obo/CHEBI_63716 |
T253 | 278-289 | Chemical | denotes | diphosphate | http://purl.obolibrary.org/obo/CHEBI_18361|http://purl.obolibrary.org/obo/CHEBI_33019 |
T255 | 302-306 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T38 | 238-253 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T146 | 0-324 | Sentence | denotes | Activation of the drug starts with the hydrolysis of the external esters followed by spontaneous release of carbon dioxide and formaldehyde to form the corresponding tenofovir, a nucleoside monophosphate, which subsequently undergoes two phosphorylation steps to form tenofovir diphosphate, the active drug (Figure S1) [64]. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
523 | 66-72 | Chemical | denotes | esters | MESH:D004952 |
524 | 108-122 | Chemical | denotes | carbon dioxide | MESH:D002245 |
525 | 127-139 | Chemical | denotes | formaldehyde | MESH:D005557 |
526 | 166-175 | Chemical | denotes | tenofovir | MESH:D000068698 |
527 | 179-203 | Chemical | denotes | nucleoside monophosphate | |
528 | 268-289 | Chemical | denotes | tenofovir diphosphate | MESH:C583447 |