> top > docs > PMC:7594251 > spans > 97021-98106 > annotations

PMC:7594251 / 97021-98106 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T211 427-434 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T682 336-342 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T683 383-389 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T684 959-960 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T652 37-43 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T653 68-74 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T654 233-238 Chemical denotes probe http://purl.obolibrary.org/obo/CHEBI_50406
T655 243-250 Chemical denotes solvent http://purl.obolibrary.org/obo/CHEBI_46787
T656 272-278 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T657 316-322 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T658 403-409 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T659 427-434 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T660 441-448 Chemical denotes ligands http://purl.obolibrary.org/obo/CHEBI_52214
T661 510-517 Chemical denotes prodrug http://purl.obolibrary.org/obo/CHEBI_50266
T662 603-610 Chemical denotes quinone http://purl.obolibrary.org/obo/CHEBI_36141
T663 925-935 Chemical denotes asparagine http://purl.obolibrary.org/obo/CHEBI_22653
T664 961-969 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T665 1021-1030 Chemical denotes aziridine http://purl.obolibrary.org/obo/CHEBI_30969
T666 1071-1078 Chemical denotes solvent http://purl.obolibrary.org/obo/CHEBI_46787

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1032 597-601 Gene denotes NQO2 Gene:4835
1033 726-730 Gene denotes NQO2 Gene:4835
1034 525-535 Chemical denotes tretazicar MESH:C100099
1035 537-576 Chemical denotes (5-(aziridin-1-yl)-2,4-dinitrobenzamide MESH:C100099
1036 587-593 Chemical denotes CB1954 MESH:C100099
1037 704-714 Chemical denotes tretazicar MESH:C100099
1038 829-839 Chemical denotes tretazicar MESH:C100099
1039 925-935 Chemical denotes asparagine MESH:D001216
1040 961-969 Chemical denotes hydrogen MESH:D006859
1041 996-1006 Chemical denotes tretazicar MESH:C100099
1042 1021-1030 Chemical denotes aziridine MESH:C033132
1043 1041-1051 Chemical denotes tretazicar MESH:C100099

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T635 0-6 Sentence denotes 3.6.5.
T636 7-13 Sentence denotes SALMON
T637 14-191 Sentence denotes Solvent accessibility, ligand binding, and mapping of ligand orientation by NMR spectroscopy (SALMON) is another method based on the data obtained via nuclear Overhauser effect.
T638 192-450 Sentence denotes This method utilizes WaterLOGSY [401] to probe for solvent accessibility to the ligand and determine the orientation of the ligand by analyzing signal changes in WaterLOGSY spectra (positive signal from unbound ligand vs. negative for protein-bound ligands).
T639 451-642 Sentence denotes This method was first used to determine the orientation of prodrug called tretazicar ((5-(aziridin-1-yl)-2,4-dinitrobenzamide) known as CB1954 in NQO2 (quinone oxidoreductase 2) binding site.
T640 643-858 Sentence denotes Previous attempts had been made to obtain the orientation of tretazicar bounded to NQO2, however the results obtained from X-ray crystallography were inconclusive as two orientations of tretazicar could be possible.
T641 859-1085 Sentence denotes The information obtained via SALMON showed that the side chain of asparagine at position 161 formed a hydrogen bond with 2-nitrogroup of tretazicar, and that the aziridine moiety of tretazicar pointed toward the solvent [401].