PMC:7589163 / 23861-24676 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T159","span":{"begin":27,"end":34},"obj":"Body_part"},{"id":"T160","span":{"begin":69,"end":73},"obj":"Body_part"},{"id":"T161","span":{"begin":391,"end":395},"obj":"Body_part"},{"id":"T162","span":{"begin":420,"end":442},"obj":"Body_part"},{"id":"T163","span":{"begin":469,"end":474},"obj":"Body_part"},{"id":"T164","span":{"begin":496,"end":503},"obj":"Body_part"},{"id":"T165","span":{"begin":519,"end":524},"obj":"Body_part"},{"id":"T166","span":{"begin":719,"end":726},"obj":"Body_part"}],"attributes":[{"id":"A159","pred":"fma_id","subj":"T159","obj":"http://purl.org/sig/ont/fma/fma12278"},{"id":"A160","pred":"fma_id","subj":"T160","obj":"http://purl.org/sig/ont/fma/fma7163"},{"id":"A161","pred":"fma_id","subj":"T161","obj":"http://purl.org/sig/ont/fma/fma7163"},{"id":"A162","pred":"fma_id","subj":"T162","obj":"http://purl.org/sig/ont/fma/fma71132"},{"id":"A163","pred":"fma_id","subj":"T163","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A164","pred":"fma_id","subj":"T164","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A165","pred":"fma_id","subj":"T165","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A166","pred":"fma_id","subj":"T166","obj":"http://purl.org/sig/ont/fma/fma7203"}],"text":"Vitamin D is a fat-soluble hormone that is mainly synthesized in the skin after exposure to ultraviolet rays from sunlight (in the form of vitamin D3), and, to a lesser extent, is derived from dietary intake in the form of either vitamin D2 or D3 (the main sources of vitamin D are fatty fish, fish oils, egg yolks, cheese, and vitamin D-fortified foods). After vitamin D is produced in the skin or absorbed through the gastrointestinal tract, it is transported to the liver by vitamin D-binding protein (VDBP). In the liver vitamin D is converted to 25 hydroxy vitamin D (25(OH)D), which is monitored to evaluate vitamin D status because of its half-life of 2–3 weeks. Next, 25 hydroxy vitamin D is transported to the kidneys, where it is finally converted to its active form, 1,25 dihydroxyvitamin D (1,25(OH)2D)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T55","span":{"begin":69,"end":73},"obj":"Body_part"},{"id":"T56","span":{"begin":305,"end":314},"obj":"Body_part"},{"id":"T57","span":{"begin":305,"end":308},"obj":"Body_part"},{"id":"T58","span":{"begin":391,"end":395},"obj":"Body_part"},{"id":"T59","span":{"begin":469,"end":474},"obj":"Body_part"},{"id":"T60","span":{"begin":519,"end":524},"obj":"Body_part"}],"attributes":[{"id":"A55","pred":"uberon_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/UBERON_0000014"},{"id":"A56","pred":"uberon_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/UBERON_0007378"},{"id":"A57","pred":"uberon_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/UBERON_0007379"},{"id":"A58","pred":"uberon_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/UBERON_0000014"},{"id":"A59","pred":"uberon_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A60","pred":"uberon_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"}],"text":"Vitamin D is a fat-soluble hormone that is mainly synthesized in the skin after exposure to ultraviolet rays from sunlight (in the form of vitamin D3), and, to a lesser extent, is derived from dietary intake in the form of either vitamin D2 or D3 (the main sources of vitamin D are fatty fish, fish oils, egg yolks, cheese, and vitamin D-fortified foods). After vitamin D is produced in the skin or absorbed through the gastrointestinal tract, it is transported to the liver by vitamin D-binding protein (VDBP). In the liver vitamin D is converted to 25 hydroxy vitamin D (25(OH)D), which is monitored to evaluate vitamin D status because of its half-life of 2–3 weeks. Next, 25 hydroxy vitamin D is transported to the kidneys, where it is finally converted to its active form, 1,25 dihydroxyvitamin D (1,25(OH)2D)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T273","span":{"begin":13,"end":14},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T274","span":{"begin":15,"end":18},"obj":"http://purl.obolibrary.org/obo/UBERON_0001013"},{"id":"T275","span":{"begin":69,"end":73},"obj":"http://purl.obolibrary.org/obo/UBERON_0000014"},{"id":"T276","span":{"begin":69,"end":73},"obj":"http://purl.obolibrary.org/obo/UBERON_0001003"},{"id":"T277","span":{"begin":69,"end":73},"obj":"http://purl.obolibrary.org/obo/UBERON_0002097"},{"id":"T278","span":{"begin":69,"end":73},"obj":"http://purl.obolibrary.org/obo/UBERON_0002199"},{"id":"T279","span":{"begin":69,"end":73},"obj":"http://www.ebi.ac.uk/efo/EFO_0000962"},{"id":"T280","span":{"begin":147,"end":149},"obj":"http://purl.obolibrary.org/obo/CLO_0002675"},{"id":"T281","span":{"begin":160,"end":161},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T282","span":{"begin":238,"end":240},"obj":"http://purl.obolibrary.org/obo/CLO_0002668"},{"id":"T283","span":{"begin":244,"end":246},"obj":"http://purl.obolibrary.org/obo/CLO_0002675"},{"id":"T284","span":{"begin":288,"end":292},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_117565"},{"id":"T285","span":{"begin":294,"end":298},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_117565"},{"id":"T286","span":{"begin":391,"end":395},"obj":"http://purl.obolibrary.org/obo/UBERON_0000014"},{"id":"T287","span":{"begin":391,"end":395},"obj":"http://purl.obolibrary.org/obo/UBERON_0001003"},{"id":"T288","span":{"begin":391,"end":395},"obj":"http://purl.obolibrary.org/obo/UBERON_0002097"},{"id":"T289","span":{"begin":391,"end":395},"obj":"http://purl.obolibrary.org/obo/UBERON_0002199"},{"id":"T290","span":{"begin":391,"end":395},"obj":"http://www.ebi.ac.uk/efo/EFO_0000962"},{"id":"T291","span":{"begin":420,"end":442},"obj":"http://purl.obolibrary.org/obo/UBERON_0005409"},{"id":"T292","span":{"begin":469,"end":474},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T293","span":{"begin":469,"end":474},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T294","span":{"begin":519,"end":524},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T295","span":{"begin":519,"end":524},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T296","span":{"begin":719,"end":726},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T297","span":{"begin":719,"end":726},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T298","span":{"begin":719,"end":726},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"},{"id":"T299","span":{"begin":765,"end":771},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"Vitamin D is a fat-soluble hormone that is mainly synthesized in the skin after exposure to ultraviolet rays from sunlight (in the form of vitamin D3), and, to a lesser extent, is derived from dietary intake in the form of either vitamin D2 or D3 (the main sources of vitamin D are fatty fish, fish oils, egg yolks, cheese, and vitamin D-fortified foods). After vitamin D is produced in the skin or absorbed through the gastrointestinal tract, it is transported to the liver by vitamin D-binding protein (VDBP). In the liver vitamin D is converted to 25 hydroxy vitamin D (25(OH)D), which is monitored to evaluate vitamin D status because of its half-life of 2–3 weeks. Next, 25 hydroxy vitamin D is transported to the kidneys, where it is finally converted to its active form, 1,25 dihydroxyvitamin D (1,25(OH)2D)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T382","span":{"begin":0,"end":9},"obj":"Chemical"},{"id":"T383","span":{"begin":0,"end":7},"obj":"Chemical"},{"id":"T384","span":{"begin":27,"end":34},"obj":"Chemical"},{"id":"T385","span":{"begin":139,"end":149},"obj":"Chemical"},{"id":"T386","span":{"begin":139,"end":146},"obj":"Chemical"},{"id":"T387","span":{"begin":230,"end":240},"obj":"Chemical"},{"id":"T388","span":{"begin":230,"end":237},"obj":"Chemical"},{"id":"T389","span":{"begin":238,"end":240},"obj":"Chemical"},{"id":"T390","span":{"begin":268,"end":277},"obj":"Chemical"},{"id":"T391","span":{"begin":268,"end":275},"obj":"Chemical"},{"id":"T392","span":{"begin":328,"end":337},"obj":"Chemical"},{"id":"T393","span":{"begin":328,"end":335},"obj":"Chemical"},{"id":"T394","span":{"begin":362,"end":371},"obj":"Chemical"},{"id":"T395","span":{"begin":362,"end":369},"obj":"Chemical"},{"id":"T396","span":{"begin":478,"end":487},"obj":"Chemical"},{"id":"T397","span":{"begin":478,"end":485},"obj":"Chemical"},{"id":"T398","span":{"begin":496,"end":503},"obj":"Chemical"},{"id":"T399","span":{"begin":525,"end":534},"obj":"Chemical"},{"id":"T400","span":{"begin":525,"end":532},"obj":"Chemical"},{"id":"T401","span":{"begin":554,"end":561},"obj":"Chemical"},{"id":"T402","span":{"begin":562,"end":571},"obj":"Chemical"},{"id":"T403","span":{"begin":562,"end":569},"obj":"Chemical"},{"id":"T404","span":{"begin":614,"end":623},"obj":"Chemical"},{"id":"T405","span":{"begin":614,"end":621},"obj":"Chemical"},{"id":"T406","span":{"begin":679,"end":686},"obj":"Chemical"},{"id":"T407","span":{"begin":687,"end":696},"obj":"Chemical"},{"id":"T408","span":{"begin":687,"end":694},"obj":"Chemical"}],"attributes":[{"id":"A382","pred":"chebi_id","subj":"T382","obj":"http://purl.obolibrary.org/obo/CHEBI_89324"},{"id":"A383","pred":"chebi_id","subj":"T383","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A384","pred":"chebi_id","subj":"T384","obj":"http://purl.obolibrary.org/obo/CHEBI_24621"},{"id":"A385","pred":"chebi_id","subj":"T385","obj":"http://purl.obolibrary.org/obo/CHEBI_28940"},{"id":"A386","pred":"chebi_id","subj":"T386","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A387","pred":"chebi_id","subj":"T387","obj":"http://purl.obolibrary.org/obo/CHEBI_28934"},{"id":"A388","pred":"chebi_id","subj":"T388","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A389","pred":"chebi_id","subj":"T389","obj":"http://purl.obolibrary.org/obo/CHEBI_29294"},{"id":"A390","pred":"chebi_id","subj":"T390","obj":"http://purl.obolibrary.org/obo/CHEBI_27300"},{"id":"A391","pred":"chebi_id","subj":"T391","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A392","pred":"chebi_id","subj":"T392","obj":"http://purl.obolibrary.org/obo/CHEBI_27300"},{"id":"A393","pred":"chebi_id","subj":"T393","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A394","pred":"chebi_id","subj":"T394","obj":"http://purl.obolibrary.org/obo/CHEBI_27300"},{"id":"A395","pred":"chebi_id","subj":"T395","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A396","pred":"chebi_id","subj":"T396","obj":"http://purl.obolibrary.org/obo/CHEBI_27300"},{"id":"A397","pred":"chebi_id","subj":"T397","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A398","pred":"chebi_id","subj":"T398","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A399","pred":"chebi_id","subj":"T399","obj":"http://purl.obolibrary.org/obo/CHEBI_27300"},{"id":"A400","pred":"chebi_id","subj":"T400","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A401","pred":"chebi_id","subj":"T401","obj":"http://purl.obolibrary.org/obo/CHEBI_43176"},{"id":"A402","pred":"chebi_id","subj":"T402","obj":"http://purl.obolibrary.org/obo/CHEBI_27300"},{"id":"A403","pred":"chebi_id","subj":"T403","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A404","pred":"chebi_id","subj":"T404","obj":"http://purl.obolibrary.org/obo/CHEBI_27300"},{"id":"A405","pred":"chebi_id","subj":"T405","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A406","pred":"chebi_id","subj":"T406","obj":"http://purl.obolibrary.org/obo/CHEBI_43176"},{"id":"A407","pred":"chebi_id","subj":"T407","obj":"http://purl.obolibrary.org/obo/CHEBI_27300"},{"id":"A408","pred":"chebi_id","subj":"T408","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"}],"text":"Vitamin D is a fat-soluble hormone that is mainly synthesized in the skin after exposure to ultraviolet rays from sunlight (in the form of vitamin D3), and, to a lesser extent, is derived from dietary intake in the form of either vitamin D2 or D3 (the main sources of vitamin D are fatty fish, fish oils, egg yolks, cheese, and vitamin D-fortified foods). After vitamin D is produced in the skin or absorbed through the gastrointestinal tract, it is transported to the liver by vitamin D-binding protein (VDBP). In the liver vitamin D is converted to 25 hydroxy vitamin D (25(OH)D), which is monitored to evaluate vitamin D status because of its half-life of 2–3 weeks. Next, 25 hydroxy vitamin D is transported to the kidneys, where it is finally converted to its active form, 1,25 dihydroxyvitamin D (1,25(OH)2D)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T85","span":{"begin":450,"end":461},"obj":"http://purl.obolibrary.org/obo/GO_0006810"},{"id":"T86","span":{"begin":700,"end":711},"obj":"http://purl.obolibrary.org/obo/GO_0006810"}],"text":"Vitamin D is a fat-soluble hormone that is mainly synthesized in the skin after exposure to ultraviolet rays from sunlight (in the form of vitamin D3), and, to a lesser extent, is derived from dietary intake in the form of either vitamin D2 or D3 (the main sources of vitamin D are fatty fish, fish oils, egg yolks, cheese, and vitamin D-fortified foods). After vitamin D is produced in the skin or absorbed through the gastrointestinal tract, it is transported to the liver by vitamin D-binding protein (VDBP). In the liver vitamin D is converted to 25 hydroxy vitamin D (25(OH)D), which is monitored to evaluate vitamin D status because of its half-life of 2–3 weeks. Next, 25 hydroxy vitamin D is transported to the kidneys, where it is finally converted to its active form, 1,25 dihydroxyvitamin D (1,25(OH)2D)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T166","span":{"begin":0,"end":355},"obj":"Sentence"},{"id":"T167","span":{"begin":356,"end":511},"obj":"Sentence"},{"id":"T168","span":{"begin":512,"end":669},"obj":"Sentence"},{"id":"T169","span":{"begin":670,"end":815},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Vitamin D is a fat-soluble hormone that is mainly synthesized in the skin after exposure to ultraviolet rays from sunlight (in the form of vitamin D3), and, to a lesser extent, is derived from dietary intake in the form of either vitamin D2 or D3 (the main sources of vitamin D are fatty fish, fish oils, egg yolks, cheese, and vitamin D-fortified foods). After vitamin D is produced in the skin or absorbed through the gastrointestinal tract, it is transported to the liver by vitamin D-binding protein (VDBP). In the liver vitamin D is converted to 25 hydroxy vitamin D (25(OH)D), which is monitored to evaluate vitamin D status because of its half-life of 2–3 weeks. Next, 25 hydroxy vitamin D is transported to the kidneys, where it is finally converted to its active form, 1,25 dihydroxyvitamin D (1,25(OH)2D)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"628","span":{"begin":478,"end":503},"obj":"Gene"},{"id":"629","span":{"begin":505,"end":509},"obj":"Gene"},{"id":"630","span":{"begin":0,"end":9},"obj":"Chemical"},{"id":"631","span":{"begin":139,"end":149},"obj":"Chemical"},{"id":"632","span":{"begin":230,"end":240},"obj":"Chemical"},{"id":"633","span":{"begin":244,"end":246},"obj":"Chemical"},{"id":"634","span":{"begin":268,"end":277},"obj":"Chemical"},{"id":"635","span":{"begin":328,"end":337},"obj":"Chemical"},{"id":"636","span":{"begin":362,"end":371},"obj":"Chemical"},{"id":"637","span":{"begin":525,"end":534},"obj":"Chemical"},{"id":"638","span":{"begin":551,"end":571},"obj":"Chemical"},{"id":"639","span":{"begin":573,"end":580},"obj":"Chemical"},{"id":"640","span":{"begin":614,"end":623},"obj":"Chemical"},{"id":"641","span":{"begin":676,"end":696},"obj":"Chemical"},{"id":"642","span":{"begin":778,"end":801},"obj":"Chemical"},{"id":"643","span":{"begin":803,"end":813},"obj":"Chemical"}],"attributes":[{"id":"A628","pred":"tao:has_database_id","subj":"628","obj":"Gene:2638"},{"id":"A629","pred":"tao:has_database_id","subj":"629","obj":"Gene:2638"},{"id":"A630","pred":"tao:has_database_id","subj":"630","obj":"MESH:D014807"},{"id":"A631","pred":"tao:has_database_id","subj":"631","obj":"MESH:D002762"},{"id":"A632","pred":"tao:has_database_id","subj":"632","obj":"MESH:D004872"},{"id":"A633","pred":"tao:has_database_id","subj":"633","obj":"MESH:D002762"},{"id":"A634","pred":"tao:has_database_id","subj":"634","obj":"MESH:D014807"},{"id":"A635","pred":"tao:has_database_id","subj":"635","obj":"MESH:D014807"},{"id":"A636","pred":"tao:has_database_id","subj":"636","obj":"MESH:D014807"},{"id":"A637","pred":"tao:has_database_id","subj":"637","obj":"MESH:D014807"},{"id":"A638","pred":"tao:has_database_id","subj":"638","obj":"MESH:C104450"},{"id":"A640","pred":"tao:has_database_id","subj":"640","obj":"MESH:D014807"},{"id":"A641","pred":"tao:has_database_id","subj":"641","obj":"MESH:C104450"},{"id":"A642","pred":"tao:has_database_id","subj":"642","obj":"MESH:C097949"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Vitamin D is a fat-soluble hormone that is mainly synthesized in the skin after exposure to ultraviolet rays from sunlight (in the form of vitamin D3), and, to a lesser extent, is derived from dietary intake in the form of either vitamin D2 or D3 (the main sources of vitamin D are fatty fish, fish oils, egg yolks, cheese, and vitamin D-fortified foods). After vitamin D is produced in the skin or absorbed through the gastrointestinal tract, it is transported to the liver by vitamin D-binding protein (VDBP). In the liver vitamin D is converted to 25 hydroxy vitamin D (25(OH)D), which is monitored to evaluate vitamin D status because of its half-life of 2–3 weeks. Next, 25 hydroxy vitamin D is transported to the kidneys, where it is finally converted to its active form, 1,25 dihydroxyvitamin D (1,25(OH)2D)."}