PMC:7589163 / 19434-20115 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T140","span":{"begin":29,"end":35},"obj":"Body_part"},{"id":"T141","span":{"begin":74,"end":80},"obj":"Body_part"},{"id":"T142","span":{"begin":226,"end":232},"obj":"Body_part"},{"id":"T143","span":{"begin":340,"end":344},"obj":"Body_part"},{"id":"T144","span":{"begin":475,"end":485},"obj":"Body_part"},{"id":"T145","span":{"begin":517,"end":522},"obj":"Body_part"}],"attributes":[{"id":"A140","pred":"fma_id","subj":"T140","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A141","pred":"fma_id","subj":"T141","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A142","pred":"fma_id","subj":"T142","obj":"http://purl.org/sig/ont/fma/fma62970"},{"id":"A143","pred":"fma_id","subj":"T143","obj":"http://purl.org/sig/ont/fma/fma256135"},{"id":"A144","pred":"fma_id","subj":"T144","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A145","pred":"fma_id","subj":"T145","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"4.2. Vitamin C Status\nNormal plasma vitamin C concentration is 50 µmol/L. Plasma ascorbate concentrations above 10 µmol/L but below 50 µmol/L represent a status with an increased risk of insufficiency. Scurvy appears when the plasma concentration falls below 10 µmol/L, which corresponds to an intake of less than 10 mg vitamin C/day and a body pool less than 300 mg [60]. It is acknowledged that vitamin C concentration declines during stress and infection, particularly in leukocytes, as it is used to protect host cells against the oxidative stress [46]. For the same reason, children exposed to smoking or environmental tobacco smoke require increased intake of vitamin C [44]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T74","span":{"begin":202,"end":208},"obj":"Disease"},{"id":"T75","span":{"begin":448,"end":457},"obj":"Disease"}],"attributes":[{"id":"A74","pred":"mondo_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/MONDO_0009412"},{"id":"A75","pred":"mondo_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"4.2. Vitamin C Status\nNormal plasma vitamin C concentration is 50 µmol/L. Plasma ascorbate concentrations above 10 µmol/L but below 50 µmol/L represent a status with an increased risk of insufficiency. Scurvy appears when the plasma concentration falls below 10 µmol/L, which corresponds to an intake of less than 10 mg vitamin C/day and a body pool less than 300 mg [60]. It is acknowledged that vitamin C concentration declines during stress and infection, particularly in leukocytes, as it is used to protect host cells against the oxidative stress [46]. For the same reason, children exposed to smoking or environmental tobacco smoke require increased intake of vitamin C [44]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T236","span":{"begin":29,"end":35},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T237","span":{"begin":74,"end":80},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T238","span":{"begin":152,"end":153},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T239","span":{"begin":226,"end":232},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T240","span":{"begin":338,"end":339},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T241","span":{"begin":517,"end":522},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T242","span":{"begin":674,"end":679},"obj":"http://purl.obolibrary.org/obo/CLO_0002128"}],"text":"4.2. Vitamin C Status\nNormal plasma vitamin C concentration is 50 µmol/L. Plasma ascorbate concentrations above 10 µmol/L but below 50 µmol/L represent a status with an increased risk of insufficiency. Scurvy appears when the plasma concentration falls below 10 µmol/L, which corresponds to an intake of less than 10 mg vitamin C/day and a body pool less than 300 mg [60]. It is acknowledged that vitamin C concentration declines during stress and infection, particularly in leukocytes, as it is used to protect host cells against the oxidative stress [46]. For the same reason, children exposed to smoking or environmental tobacco smoke require increased intake of vitamin C [44]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T310","span":{"begin":5,"end":14},"obj":"Chemical"},{"id":"T313","span":{"begin":5,"end":12},"obj":"Chemical"},{"id":"T314","span":{"begin":36,"end":45},"obj":"Chemical"},{"id":"T315","span":{"begin":36,"end":43},"obj":"Chemical"},{"id":"T316","span":{"begin":81,"end":90},"obj":"Chemical"},{"id":"T317","span":{"begin":320,"end":329},"obj":"Chemical"},{"id":"T318","span":{"begin":320,"end":327},"obj":"Chemical"},{"id":"T319","span":{"begin":397,"end":406},"obj":"Chemical"},{"id":"T320","span":{"begin":397,"end":404},"obj":"Chemical"},{"id":"T321","span":{"begin":666,"end":675},"obj":"Chemical"},{"id":"T322","span":{"begin":666,"end":673},"obj":"Chemical"}],"attributes":[{"id":"A310","pred":"chebi_id","subj":"T310","obj":"http://purl.obolibrary.org/obo/CHEBI_21241"},{"id":"A311","pred":"chebi_id","subj":"T310","obj":"http://purl.obolibrary.org/obo/CHEBI_29073"},{"id":"A312","pred":"chebi_id","subj":"T310","obj":"http://purl.obolibrary.org/obo/CHEBI_38290"},{"id":"A313","pred":"chebi_id","subj":"T313","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A314","pred":"chebi_id","subj":"T314","obj":"http://purl.obolibrary.org/obo/CHEBI_21241"},{"id":"A315","pred":"chebi_id","subj":"T315","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A316","pred":"chebi_id","subj":"T316","obj":"http://purl.obolibrary.org/obo/CHEBI_22651"},{"id":"A317","pred":"chebi_id","subj":"T317","obj":"http://purl.obolibrary.org/obo/CHEBI_21241"},{"id":"A318","pred":"chebi_id","subj":"T318","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A319","pred":"chebi_id","subj":"T319","obj":"http://purl.obolibrary.org/obo/CHEBI_21241"},{"id":"A320","pred":"chebi_id","subj":"T320","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"},{"id":"A321","pred":"chebi_id","subj":"T321","obj":"http://purl.obolibrary.org/obo/CHEBI_21241"},{"id":"A322","pred":"chebi_id","subj":"T322","obj":"http://purl.obolibrary.org/obo/CHEBI_33229"}],"text":"4.2. Vitamin C Status\nNormal plasma vitamin C concentration is 50 µmol/L. Plasma ascorbate concentrations above 10 µmol/L but below 50 µmol/L represent a status with an increased risk of insufficiency. Scurvy appears when the plasma concentration falls below 10 µmol/L, which corresponds to an intake of less than 10 mg vitamin C/day and a body pool less than 300 mg [60]. It is acknowledged that vitamin C concentration declines during stress and infection, particularly in leukocytes, as it is used to protect host cells against the oxidative stress [46]. For the same reason, children exposed to smoking or environmental tobacco smoke require increased intake of vitamin C [44]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T31","span":{"begin":247,"end":252},"obj":"Phenotype"},{"id":"T32","span":{"begin":535,"end":551},"obj":"Phenotype"}],"attributes":[{"id":"A31","pred":"hp_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/HP_0002527"},{"id":"A32","pred":"hp_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/HP_0025464"}],"text":"4.2. Vitamin C Status\nNormal plasma vitamin C concentration is 50 µmol/L. Plasma ascorbate concentrations above 10 µmol/L but below 50 µmol/L represent a status with an increased risk of insufficiency. Scurvy appears when the plasma concentration falls below 10 µmol/L, which corresponds to an intake of less than 10 mg vitamin C/day and a body pool less than 300 mg [60]. It is acknowledged that vitamin C concentration declines during stress and infection, particularly in leukocytes, as it is used to protect host cells against the oxidative stress [46]. For the same reason, children exposed to smoking or environmental tobacco smoke require increased intake of vitamin C [44]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T133","span":{"begin":0,"end":4},"obj":"Sentence"},{"id":"T134","span":{"begin":5,"end":21},"obj":"Sentence"},{"id":"T135","span":{"begin":22,"end":73},"obj":"Sentence"},{"id":"T136","span":{"begin":74,"end":201},"obj":"Sentence"},{"id":"T137","span":{"begin":202,"end":372},"obj":"Sentence"},{"id":"T138","span":{"begin":373,"end":557},"obj":"Sentence"},{"id":"T139","span":{"begin":558,"end":681},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"4.2. Vitamin C Status\nNormal plasma vitamin C concentration is 50 µmol/L. Plasma ascorbate concentrations above 10 µmol/L but below 50 µmol/L represent a status with an increased risk of insufficiency. Scurvy appears when the plasma concentration falls below 10 µmol/L, which corresponds to an intake of less than 10 mg vitamin C/day and a body pool less than 300 mg [60]. It is acknowledged that vitamin C concentration declines during stress and infection, particularly in leukocytes, as it is used to protect host cells against the oxidative stress [46]. For the same reason, children exposed to smoking or environmental tobacco smoke require increased intake of vitamin C [44]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"459","span":{"begin":5,"end":14},"obj":"Chemical"},{"id":"473","span":{"begin":579,"end":587},"obj":"Species"},{"id":"474","span":{"begin":624,"end":631},"obj":"Species"},{"id":"475","span":{"begin":267,"end":268},"obj":"Gene"},{"id":"476","span":{"begin":140,"end":141},"obj":"Gene"},{"id":"477","span":{"begin":120,"end":121},"obj":"Gene"},{"id":"478","span":{"begin":71,"end":72},"obj":"Gene"},{"id":"479","span":{"begin":36,"end":45},"obj":"Chemical"},{"id":"480","span":{"begin":81,"end":90},"obj":"Chemical"},{"id":"481","span":{"begin":320,"end":329},"obj":"Chemical"},{"id":"482","span":{"begin":397,"end":406},"obj":"Chemical"},{"id":"483","span":{"begin":666,"end":675},"obj":"Chemical"},{"id":"484","span":{"begin":187,"end":200},"obj":"Disease"},{"id":"485","span":{"begin":448,"end":457},"obj":"Disease"}],"attributes":[{"id":"A459","pred":"tao:has_database_id","subj":"459","obj":"MESH:D001205"},{"id":"A473","pred":"tao:has_database_id","subj":"473","obj":"Tax:9606"},{"id":"A474","pred":"tao:has_database_id","subj":"474","obj":"Tax:4097"},{"id":"A475","pred":"tao:has_database_id","subj":"475","obj":"Gene:21832"},{"id":"A476","pred":"tao:has_database_id","subj":"476","obj":"Gene:21832"},{"id":"A477","pred":"tao:has_database_id","subj":"477","obj":"Gene:21832"},{"id":"A478","pred":"tao:has_database_id","subj":"478","obj":"Gene:21832"},{"id":"A479","pred":"tao:has_database_id","subj":"479","obj":"MESH:D001205"},{"id":"A480","pred":"tao:has_database_id","subj":"480","obj":"MESH:D001205"},{"id":"A481","pred":"tao:has_database_id","subj":"481","obj":"MESH:D001205"},{"id":"A482","pred":"tao:has_database_id","subj":"482","obj":"MESH:D001205"},{"id":"A483","pred":"tao:has_database_id","subj":"483","obj":"MESH:D001205"},{"id":"A484","pred":"tao:has_database_id","subj":"484","obj":"MESH:D000309"},{"id":"A485","pred":"tao:has_database_id","subj":"485","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"4.2. Vitamin C Status\nNormal plasma vitamin C concentration is 50 µmol/L. Plasma ascorbate concentrations above 10 µmol/L but below 50 µmol/L represent a status with an increased risk of insufficiency. Scurvy appears when the plasma concentration falls below 10 µmol/L, which corresponds to an intake of less than 10 mg vitamin C/day and a body pool less than 300 mg [60]. It is acknowledged that vitamin C concentration declines during stress and infection, particularly in leukocytes, as it is used to protect host cells against the oxidative stress [46]. For the same reason, children exposed to smoking or environmental tobacco smoke require increased intake of vitamin C [44]."}