PMC:7589163 / 19434-20115 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7589163","sourcedb":"PMC","sourceid":"7589163","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7589163","text":"4.2. Vitamin C Status\nNormal plasma vitamin C concentration is 50 µmol/L. Plasma ascorbate concentrations above 10 µmol/L but below 50 µmol/L represent a status with an increased risk of insufficiency. Scurvy appears when the plasma concentration falls below 10 µmol/L, which corresponds to an intake of less than 10 mg vitamin C/day and a body pool less than 300 mg [60]. It is acknowledged that vitamin C concentration declines during stress and infection, particularly in leukocytes, as it is used to protect host cells against the oxidative stress [46]. For the same reason, children exposed to smoking or environmental tobacco smoke require increased intake of vitamin C 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