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PMC:7574920 / 36311-37004 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T143 39-42 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T144 157-160 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T83 292-300 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T310 230-232 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T311 314-318 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T312 364-365 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T313 538-540 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T314 545-546 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T315 577-579 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T316 639-645 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T71 474-489 Chemical denotes oligonucleotide http://purl.obolibrary.org/obo/CHEBI_7754

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
252 292-302 Species denotes SARS-CoV-2 Tax:2697049
253 474-489 Chemical denotes oligonucleotide MESH:D009841

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T271 0-204 Sentence denotes Although spike-in experiments with IVT RNA can be informative, we have experienced clear differences when comparing such experiments to those using clinical RNA samples isolated from swab specimens (figs.
T272 205-234 Sentence denotes S6 and S7, and data file S1).
T273 235-410 Sentence denotes We therefore recommend validating any new proposed rapid SARS-CoV-2 diagnostic test using “real-life” clinical samples including a large fraction of negative clinical samples.
T274 411-595 Sentence denotes To overcome the problem of spurious amplification, an expanded oligonucleotide set that incorporates sequence-specific probes (34) or a CRISPR/Cas12a–based approach (36) could be used.
T275 596-693 Sentence denotes However, these applications have yet to be tested with large numbers of diverse clinical samples.