PMC:7574920 / 31217-32104 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T124","span":{"begin":647,"end":651},"obj":"Body_part"},{"id":"T125","span":{"begin":808,"end":812},"obj":"Body_part"}],"attributes":[{"id":"A124","pred":"fma_id","subj":"T124","obj":"http://purl.org/sig/ont/fma/fma12520"},{"id":"A125","pred":"fma_id","subj":"T125","obj":"http://purl.org/sig/ont/fma/fma12520"}],"text":"Colorimetric readouts of the swab–to–RT-LAMP assay over time.\n(A) The colorimetric readouts (ΔOD) for the direct (left) and hot (right) swab–to–RT-LAMP assays were assessed every 10 min. Heterogeneity is notable at the early time points. ΔOD values at the zero time point were not measured for the hot swab–to–RT-LAMP assay. Also, the 40-min time point was not available for one plate. The kink in some lines at 30 min (right) was due to a transient equipment malfunction. (B) Comparison of two scoring schemes. The readout used in Fig. 5 to score the direct (left) and hot (right) swab–to–RT-LAMP assays, namely, ΔOD at 30 min, is shown on the y axis, and compared to an alternative score, namely, the difference between the ΔOD signals at 30 min and at 10 min after the start of incubation, shown on the x axis. The latter shows better separation between positive and negative samples."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T73","span":{"begin":94,"end":96},"obj":"Disease"},{"id":"T74","span":{"begin":239,"end":241},"obj":"Disease"},{"id":"T75","span":{"begin":615,"end":617},"obj":"Disease"},{"id":"T76","span":{"begin":727,"end":729},"obj":"Disease"}],"attributes":[{"id":"A73","pred":"mondo_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/MONDO_0017178"},{"id":"A74","pred":"mondo_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/MONDO_0017178"},{"id":"A75","pred":"mondo_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/MONDO_0017178"},{"id":"A76","pred":"mondo_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/MONDO_0017178"}],"text":"Colorimetric readouts of the swab–to–RT-LAMP assay over time.\n(A) The colorimetric readouts (ΔOD) for the direct (left) and hot (right) swab–to–RT-LAMP assays were assessed every 10 min. Heterogeneity is notable at the early time points. ΔOD values at the zero time point were not measured for the hot swab–to–RT-LAMP assay. Also, the 40-min time point was not available for one plate. The kink in some lines at 30 min (right) was due to a transient equipment malfunction. (B) Comparison of two scoring schemes. The readout used in Fig. 5 to score the direct (left) and hot (right) swab–to–RT-LAMP assays, namely, ΔOD at 30 min, is shown on the y axis, and compared to an alternative score, namely, the difference between the ΔOD signals at 30 min and at 10 min after the start of incubation, shown on the x axis. The latter shows better separation between positive and negative samples."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T275","span":{"begin":63,"end":64},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T276","span":{"begin":438,"end":439},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T277","span":{"begin":474,"end":475},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T278","span":{"begin":730,"end":737},"obj":"http://purl.obolibrary.org/obo/SO_0000418"}],"text":"Colorimetric readouts of the swab–to–RT-LAMP assay over time.\n(A) The colorimetric readouts (ΔOD) for the direct (left) and hot (right) swab–to–RT-LAMP assays were assessed every 10 min. Heterogeneity is notable at the early time points. ΔOD values at the zero time point were not measured for the hot swab–to–RT-LAMP assay. Also, the 40-min time point was not available for one plate. The kink in some lines at 30 min (right) was due to a transient equipment malfunction. (B) Comparison of two scoring schemes. The readout used in Fig. 5 to score the direct (left) and hot (right) swab–to–RT-LAMP assays, namely, ΔOD at 30 min, is shown on the y axis, and compared to an alternative score, namely, the difference between the ΔOD signals at 30 min and at 10 min after the start of incubation, shown on the x axis. The latter shows better separation between positive and negative samples."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T189","span":{"begin":37,"end":39},"obj":"http://purl.obolibrary.org/obo/GO_0001171"},{"id":"T190","span":{"begin":144,"end":146},"obj":"http://purl.obolibrary.org/obo/GO_0001171"},{"id":"T191","span":{"begin":310,"end":312},"obj":"http://purl.obolibrary.org/obo/GO_0001171"},{"id":"T192","span":{"begin":590,"end":592},"obj":"http://purl.obolibrary.org/obo/GO_0001171"}],"text":"Colorimetric readouts of the swab–to–RT-LAMP assay over time.\n(A) The colorimetric readouts (ΔOD) for the direct (left) and hot (right) swab–to–RT-LAMP assays were assessed every 10 min. Heterogeneity is notable at the early time points. ΔOD values at the zero time point were not measured for the hot swab–to–RT-LAMP assay. Also, the 40-min time point was not available for one plate. The kink in some lines at 30 min (right) was due to a transient equipment malfunction. (B) Comparison of two scoring schemes. The readout used in Fig. 5 to score the direct (left) and hot (right) swab–to–RT-LAMP assays, namely, ΔOD at 30 min, is shown on the y axis, and compared to an alternative score, namely, the difference between the ΔOD signals at 30 min and at 10 min after the start of incubation, shown on the x axis. The latter shows better separation between positive and negative samples."}

{"project":"LitCovid-sentences","denotations":[{"id":"T240","span":{"begin":62,"end":186},"obj":"Sentence"},{"id":"T241","span":{"begin":187,"end":324},"obj":"Sentence"},{"id":"T242","span":{"begin":325,"end":385},"obj":"Sentence"},{"id":"T243","span":{"begin":386,"end":511},"obj":"Sentence"},{"id":"T244","span":{"begin":512,"end":813},"obj":"Sentence"},{"id":"T245","span":{"begin":814,"end":887},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Colorimetric readouts of the swab–to–RT-LAMP assay over time.\n(A) The colorimetric readouts (ΔOD) for the direct (left) and hot (right) swab–to–RT-LAMP assays were assessed every 10 min. Heterogeneity is notable at the early time points. ΔOD values at the zero time point were not measured for the hot swab–to–RT-LAMP assay. Also, the 40-min time point was not available for one plate. The kink in some lines at 30 min (right) was due to a transient equipment malfunction. (B) Comparison of two scoring schemes. The readout used in Fig. 5 to score the direct (left) and hot (right) swab–to–RT-LAMP assays, namely, ΔOD at 30 min, is shown on the y axis, and compared to an alternative score, namely, the difference between the ΔOD signals at 30 min and at 10 min after the start of incubation, shown on the x axis. The latter shows better separation between positive and negative samples."}