PMC:7574920 / 28792-29619 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T122","span":{"begin":21,"end":24},"obj":"Body_part"}],"attributes":[{"id":"A122","pred":"fma_id","subj":"T122","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"(A) Skipping a prior RNA isolation step, pharyngeal swab samples were subjected to the RT-LAMP assay either directly (left) or after 5 min of heat treatment at 95°C (right). For each sample, scatter plots are used to compare the swab–to–RT-LAMP assay results (ΔOD values) with the results of RT-qPCR (CT values). The measurement time point was 30 min after the start of the 65°C incubation. (B) Shown is the sensitivity (right) and specificity (left) of the swab–to–RT-LAMP assay [derived from the data in (A)] using the decision threshold indicated by the horizontal gray line in (A). Specificity and sensitivity values (thick lines) are shown with their 95% confidence intervals (boxes) as in Fig. 3, with blue indicating the direct swab–to–RT-LAMP assay and red indicating the hot swab–to–RT-LAMP assay. (Also see table S3)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T70","span":{"begin":261,"end":263},"obj":"Disease"}],"attributes":[{"id":"A70","pred":"mondo_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/MONDO_0017178"}],"text":"(A) Skipping a prior RNA isolation step, pharyngeal swab samples were subjected to the RT-LAMP assay either directly (left) or after 5 min of heat treatment at 95°C (right). For each sample, scatter plots are used to compare the swab–to–RT-LAMP assay results (ΔOD values) with the results of RT-qPCR (CT values). The measurement time point was 30 min after the start of the 65°C incubation. (B) Shown is the sensitivity (right) and specificity (left) of the swab–to–RT-LAMP assay [derived from the data in (A)] using the decision threshold indicated by the horizontal gray line in (A). Specificity and sensitivity values (thick lines) are shown with their 95% confidence intervals (boxes) as in Fig. 3, with blue indicating the direct swab–to–RT-LAMP assay and red indicating the hot swab–to–RT-LAMP assay. (Also see table S3)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T256","span":{"begin":1,"end":2},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T257","span":{"begin":13,"end":14},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T258","span":{"begin":392,"end":393},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T259","span":{"begin":507,"end":508},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T260","span":{"begin":582,"end":583},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"(A) Skipping a prior RNA isolation step, pharyngeal swab samples were subjected to the RT-LAMP assay either directly (left) or after 5 min of heat treatment at 95°C (right). For each sample, scatter plots are used to compare the swab–to–RT-LAMP assay results (ΔOD values) with the results of RT-qPCR (CT values). The measurement time point was 30 min after the start of the 65°C incubation. (B) Shown is the sensitivity (right) and specificity (left) of the swab–to–RT-LAMP assay [derived from the data in (A)] using the decision threshold indicated by the horizontal gray line in (A). Specificity and sensitivity values (thick lines) are shown with their 95% confidence intervals (boxes) as in Fig. 3, with blue indicating the direct swab–to–RT-LAMP assay and red indicating the hot swab–to–RT-LAMP assay. (Also see table S3)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T65","span":{"begin":823,"end":825},"obj":"Chemical"}],"attributes":[{"id":"A65","pred":"chebi_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/CHEBI_29388"}],"text":"(A) Skipping a prior RNA isolation step, pharyngeal swab samples were subjected to the RT-LAMP assay either directly (left) or after 5 min of heat treatment at 95°C (right). For each sample, scatter plots are used to compare the swab–to–RT-LAMP assay results (ΔOD values) with the results of RT-qPCR (CT values). The measurement time point was 30 min after the start of the 65°C incubation. (B) Shown is the sensitivity (right) and specificity (left) of the swab–to–RT-LAMP assay [derived from the data in (A)] using the decision threshold indicated by the horizontal gray line in (A). Specificity and sensitivity values (thick lines) are shown with their 95% confidence intervals (boxes) as in Fig. 3, with blue indicating the direct swab–to–RT-LAMP assay and red indicating the hot swab–to–RT-LAMP assay. (Also see table S3)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T170","span":{"begin":87,"end":89},"obj":"http://purl.obolibrary.org/obo/GO_0001171"},{"id":"T171","span":{"begin":237,"end":239},"obj":"http://purl.obolibrary.org/obo/GO_0001171"},{"id":"T172","span":{"begin":292,"end":294},"obj":"http://purl.obolibrary.org/obo/GO_0001171"},{"id":"T173","span":{"begin":466,"end":468},"obj":"http://purl.obolibrary.org/obo/GO_0001171"},{"id":"T174","span":{"begin":743,"end":745},"obj":"http://purl.obolibrary.org/obo/GO_0001171"},{"id":"T175","span":{"begin":792,"end":794},"obj":"http://purl.obolibrary.org/obo/GO_0001171"}],"text":"(A) Skipping a prior RNA isolation step, pharyngeal swab samples were subjected to the RT-LAMP assay either directly (left) or after 5 min of heat treatment at 95°C (right). For each sample, scatter plots are used to compare the swab–to–RT-LAMP assay results (ΔOD values) with the results of RT-qPCR (CT values). The measurement time point was 30 min after the start of the 65°C incubation. (B) Shown is the sensitivity (right) and specificity (left) of the swab–to–RT-LAMP assay [derived from the data in (A)] using the decision threshold indicated by the horizontal gray line in (A). Specificity and sensitivity values (thick lines) are shown with their 95% confidence intervals (boxes) as in Fig. 3, with blue indicating the direct swab–to–RT-LAMP assay and red indicating the hot swab–to–RT-LAMP assay. (Also see table S3)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T209","span":{"begin":0,"end":173},"obj":"Sentence"},{"id":"T210","span":{"begin":174,"end":312},"obj":"Sentence"},{"id":"T211","span":{"begin":313,"end":585},"obj":"Sentence"},{"id":"T212","span":{"begin":586,"end":827},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"(A) Skipping a prior RNA isolation step, pharyngeal swab samples were subjected to the RT-LAMP assay either directly (left) or after 5 min of heat treatment at 95°C (right). For each sample, scatter plots are used to compare the swab–to–RT-LAMP assay results (ΔOD values) with the results of RT-qPCR (CT values). The measurement time point was 30 min after the start of the 65°C incubation. (B) Shown is the sensitivity (right) and specificity (left) of the swab–to–RT-LAMP assay [derived from the data in (A)] using the decision threshold indicated by the horizontal gray line in (A). Specificity and sensitivity values (thick lines) are shown with their 95% confidence intervals (boxes) as in Fig. 3, with blue indicating the direct swab–to–RT-LAMP assay and red indicating the hot swab–to–RT-LAMP assay. (Also see table S3)."}