> top > docs > PMC:7571312 > spans > 89194-90525 > annotations

PMC:7571312 / 89194-90525 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T632 537-538 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T633 658-660 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T634 688-689 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T635 1107-1109 http://purl.obolibrary.org/obo/CLO_0007874 denotes MS
T636 1142-1147 http://purl.obolibrary.org/obo/CLO_0007706 denotes M + H

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1611 30-33 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T1612 64-70 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T1614 71-77 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T1615 78-83 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T1616 84-92 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T1617 93-99 Chemical denotes pentyl http://purl.obolibrary.org/obo/CHEBI_25902
T1618 103-110 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T1620 111-120 Chemical denotes 1H-indole http://purl.obolibrary.org/obo/CHEBI_16881
T1621 111-113 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1622 114-120 Chemical denotes indole http://purl.obolibrary.org/obo/CHEBI_35581
T1623 123-134 Chemical denotes carboxamide http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622
T1625 217-224 Chemical denotes hydroxy http://purl.obolibrary.org/obo/CHEBI_43176
T1626 227-230 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T1627 261-267 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T1629 268-274 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T1630 275-280 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T1631 281-289 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T1632 291-304 Chemical denotes 3-methylbutyl http://purl.obolibrary.org/obo/CHEBI_30359
T1633 308-315 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T1635 316-325 Chemical denotes 1H-indole http://purl.obolibrary.org/obo/CHEBI_16881
T1636 316-318 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1637 319-325 Chemical denotes indole http://purl.obolibrary.org/obo/CHEBI_35581
T1638 328-339 Chemical denotes carboxamide http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622
T1640 380-386 Chemical denotes chloro http://purl.obolibrary.org/obo/CHEBI_47853
T1641 389-392 Chemical denotes oxo http://purl.obolibrary.org/obo/CHEBI_46629
T1642 423-429 Chemical denotes methyl http://purl.obolibrary.org/obo/CHEBI_32875|http://purl.obolibrary.org/obo/CHEBI_29309
T1644 430-436 Chemical denotes propyl http://purl.obolibrary.org/obo/CHEBI_26308
T1645 437-442 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T1646 443-451 Chemical denotes carbonyl http://purl.obolibrary.org/obo/CHEBI_23019
T1647 452-458 Chemical denotes pentyl http://purl.obolibrary.org/obo/CHEBI_25902
T1648 462-469 Chemical denotes methoxy http://purl.obolibrary.org/obo/CHEBI_32772|http://purl.obolibrary.org/obo/CHEBI_44520
T1650 470-479 Chemical denotes 1H-indole http://purl.obolibrary.org/obo/CHEBI_16881
T1651 470-472 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1652 473-479 Chemical denotes indole http://purl.obolibrary.org/obo/CHEBI_35581
T1653 482-493 Chemical denotes carboxamide http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622
T1655 620-628 Chemical denotes methanol http://purl.obolibrary.org/obo/CHEBI_17790
T1656 629-639 Chemical denotes chloroform http://purl.obolibrary.org/obo/CHEBI_35255
T1657 702-704 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1658 710-714 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T1659 731-733 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1660 755-757 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1661 779-781 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1662 793-795 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1663 807-809 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1664 831-833 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1665 855-857 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1666 879-881 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1667 903-905 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1668 946-948 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1669 975-977 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1670 1017-1019 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1671 1031-1033 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1672 1045-1047 Chemical denotes 1H http://purl.obolibrary.org/obo/CHEBI_49637
T1673 1107-1109 Chemical denotes MS http://purl.obolibrary.org/obo/CHEBI_73613
T1674 1182-1185 Chemical denotes H2O http://purl.obolibrary.org/obo/CHEBI_15377
T1675 1190-1203 Chemical denotes ethyl acetate http://purl.obolibrary.org/obo/CHEBI_27750
T1676 1190-1195 Chemical denotes ethyl http://purl.obolibrary.org/obo/CHEBI_37807|http://purl.obolibrary.org/obo/CHEBI_62801
T1678 1196-1203 Chemical denotes acetate http://purl.obolibrary.org/obo/CHEBI_30089|http://purl.obolibrary.org/obo/CHEBI_47622

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T516 0-139 Sentence denotes N-((1S)-1-{[((1S)-3-Hydroxy-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]carbonyl}pentyl)-4-methoxy-1H-indole-2-carboxamide (39)
T517 140-557 Sentence denotes Following the procedure described for the preparation of N-((1S)-1-{[((1S)-3-hydroxy-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]carbonyl}-3-methylbutyl)-4-methoxy-1H-indole-2-carboxamide but substituting of N-((1S)-1-{[((1S)-3-chloro-2-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}propyl)amino]carbonyl}pentyl)-4-methoxy-1H-indole-2-carboxamide and making noncritical variations provided a crude yellow foam.
T518 558-701 Sentence denotes This material was purified by Biotage MPLC (25 M column, 5–6% methanol/chloroform) to afford 82 mg (35%) of the title compound as a white foam.
T519 702-1233 Sentence denotes 1H NMR (DMSO-d6) δ 11.57 (s, 1H), 8.42 (d, J = 8 Hz, 1H), 8.38 (d, J = 8 Hz, 1H), 7.62 (s, 1H), 7.35 (s, 1H), 7.09 (t, J = 8 Hz, 1H), 6.99 (d, J = 8 Hz, 1H), 6.49 (d, J = 8 Hz, 1H), 5.06 (t, J = 8 Hz, 1H), 4.44 (m, 2H), 4.25 (dd, J = 8, 20 Hz, 1H), 4.14 (dd, J = 8, 20 Hz, 1H), 3.87 (s, 3H), 3.08 (m, 2H), 2.28 (m, 1H), 2.10 (m, 1H), 1.91 (m, 1H), 1.74–1.54 (m, 4H), 1.32 (m, 4H), 0.87 (t, J = 8 Hz, 3H); MS (ESI+) for C24H32N4O6m/z 473.2 (M + H)+; anal. calcd for C24H32N4O6·0.6 H2O·0.2 ethyl acetate: C, 59.46; H, 7.01; N, 11.18.
T520 1234-1331 Sentence denotes Found: C, 53.37; H, 6.94; N, 11.23; HRMS (ESI+) calcd for C24H32N4O6+H1 473.2395, found 473.2382.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1747 620-628 Chemical denotes methanol MESH:D000432
1748 629-639 Chemical denotes chloroform MESH:D002725
1749 1167-1177 Chemical denotes C24H32N4O6
1750 1182-1185 Chemical denotes H2O
1751 1190-1203 Chemical denotes ethyl acetate MESH:C007650
1752 1205-1206 Chemical denotes C MESH:D002244
1753 1224-1225 Chemical denotes N MESH:D009584
1754 1241-1242 Chemical denotes C MESH:D002244
1755 1260-1261 Chemical denotes N MESH:D009584
1756 1292-1302 Chemical denotes C24H32N4O6
1757 1270-1274 Disease denotes HRMS