PMC:7565665 / 68214-68421 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T438","span":{"begin":147,"end":154},"obj":"Body_part"},{"id":"T439","span":{"begin":171,"end":186},"obj":"Body_part"}],"attributes":[{"id":"A438","pred":"fma_id","subj":"T438","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A439","pred":"fma_id","subj":"T439","obj":"http://purl.org/sig/ont/fma/fma63841"}],"text":"Two of our recent studies demonstrated that cysteamine-based dendrimers were able to not only decrease ΔF508-CFTR aggregation, but also rescue the protein to increase the plasma membrane expression [45,149]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T789","span":{"begin":109,"end":113},"obj":"http://purl.obolibrary.org/obo/PR_000001044"},{"id":"T790","span":{"begin":171,"end":177},"obj":"http://purl.obolibrary.org/obo/UBERON_0001969"},{"id":"T791","span":{"begin":178,"end":186},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"}],"text":"Two of our recent studies demonstrated that cysteamine-based dendrimers were able to not only decrease ΔF508-CFTR aggregation, but also rescue the protein to increase the plasma membrane expression [45,149]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T158","span":{"begin":44,"end":54},"obj":"Chemical"},{"id":"T55491","span":{"begin":147,"end":154},"obj":"Chemical"}],"attributes":[{"id":"A87411","pred":"chebi_id","subj":"T158","obj":"http://purl.obolibrary.org/obo/CHEBI_17141"},{"id":"A77503","pred":"chebi_id","subj":"T158","obj":"http://purl.obolibrary.org/obo/CHEBI_58029"},{"id":"A62563","pred":"chebi_id","subj":"T55491","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Two of our recent studies demonstrated that cysteamine-based dendrimers were able to not only decrease ΔF508-CFTR aggregation, but also rescue the protein to increase the plasma membrane expression [45,149]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1699","span":{"begin":109,"end":113},"obj":"Gene"},{"id":"1707","span":{"begin":44,"end":54},"obj":"Chemical"}],"attributes":[{"id":"A1699","pred":"tao:has_database_id","subj":"1699","obj":"Gene:1080"},{"id":"A1707","pred":"tao:has_database_id","subj":"1707","obj":"MESH:D003543"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Two of our recent studies demonstrated that cysteamine-based dendrimers were able to not only decrease ΔF508-CFTR aggregation, but also rescue the protein to increase the plasma membrane expression [45,149]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T904","span":{"begin":109,"end":113},"obj":"http://purl.obolibrary.org/obo/GO_0005260"}],"text":"Two of our recent studies demonstrated that cysteamine-based dendrimers were able to not only decrease ΔF508-CFTR aggregation, but also rescue the protein to increase the plasma membrane expression [45,149]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T356","span":{"begin":0,"end":207},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Two of our recent studies demonstrated that cysteamine-based dendrimers were able to not only decrease ΔF508-CFTR aggregation, but also rescue the protein to increase the plasma membrane expression [45,149]."}