PMC:7565665 / 5746-6073 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T34","span":{"begin":214,"end":222},"obj":"Body_part"}],"attributes":[{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma264783"}],"text":"We and others have demonstrated that autophagy impairment is the key central mechanism for tobacco, biomass smoke or e-cigarette vapor (eCV) exposure and the age-related induction of inflammatory-oxidative stress, alveolar apoptosis and senescence, leading to COPD-emphysema pathogenesis and progression [33,34,35,36,37,38,39]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T66","span":{"begin":260,"end":264},"obj":"Disease"},{"id":"T67","span":{"begin":265,"end":274},"obj":"Disease"}],"attributes":[{"id":"A66","pred":"mondo_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/MONDO_0005002"},{"id":"A67","pred":"mondo_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/MONDO_0004849"}],"text":"We and others have demonstrated that autophagy impairment is the key central mechanism for tobacco, biomass smoke or e-cigarette vapor (eCV) exposure and the age-related induction of inflammatory-oxidative stress, alveolar apoptosis and senescence, leading to COPD-emphysema pathogenesis and progression [33,34,35,36,37,38,39]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"117","span":{"begin":91,"end":98},"obj":"Species"},{"id":"120","span":{"begin":260,"end":274},"obj":"Disease"}],"attributes":[{"id":"A117","pred":"tao:has_database_id","subj":"117","obj":"Tax:4097"},{"id":"A120","pred":"tao:has_database_id","subj":"120","obj":"MESH:D029424"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"We and others have demonstrated that autophagy impairment is the key central mechanism for tobacco, biomass smoke or e-cigarette vapor (eCV) exposure and the age-related induction of inflammatory-oxidative stress, alveolar apoptosis and senescence, leading to COPD-emphysema pathogenesis and progression [33,34,35,36,37,38,39]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T26","span":{"begin":196,"end":212},"obj":"Phenotype"},{"id":"T27","span":{"begin":260,"end":264},"obj":"Phenotype"},{"id":"T28","span":{"begin":265,"end":274},"obj":"Phenotype"}],"attributes":[{"id":"A26","pred":"hp_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/HP_0025464"},{"id":"A27","pred":"hp_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/HP_0006510"},{"id":"A28","pred":"hp_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/HP_0002097"}],"text":"We and others have demonstrated that autophagy impairment is the key central mechanism for tobacco, biomass smoke or e-cigarette vapor (eCV) exposure and the age-related induction of inflammatory-oxidative stress, alveolar apoptosis and senescence, leading to COPD-emphysema pathogenesis and progression [33,34,35,36,37,38,39]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T56","span":{"begin":37,"end":46},"obj":"http://purl.obolibrary.org/obo/GO_0016236"},{"id":"T57","span":{"begin":37,"end":46},"obj":"http://purl.obolibrary.org/obo/GO_0006914"},{"id":"T58","span":{"begin":223,"end":232},"obj":"http://purl.obolibrary.org/obo/GO_0097194"},{"id":"T59","span":{"begin":223,"end":232},"obj":"http://purl.obolibrary.org/obo/GO_0006915"},{"id":"T60","span":{"begin":275,"end":287},"obj":"http://purl.obolibrary.org/obo/GO_0009405"}],"text":"We and others have demonstrated that autophagy impairment is the key central mechanism for tobacco, biomass smoke or e-cigarette vapor (eCV) exposure and the age-related induction of inflammatory-oxidative stress, alveolar apoptosis and senescence, leading to COPD-emphysema pathogenesis and progression [33,34,35,36,37,38,39]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T27","span":{"begin":0,"end":327},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"We and others have demonstrated that autophagy impairment is the key central mechanism for tobacco, biomass smoke or e-cigarette vapor (eCV) exposure and the age-related induction of inflammatory-oxidative stress, alveolar apoptosis and senescence, leading to COPD-emphysema pathogenesis and progression [33,34,35,36,37,38,39]."}