PMC:7565665 / 10561-10849 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T65","span":{"begin":57,"end":66},"obj":"Body_part"},{"id":"T66","span":{"begin":168,"end":176},"obj":"Body_part"},{"id":"T67","span":{"begin":232,"end":236},"obj":"Body_part"}],"attributes":[{"id":"A65","pred":"fma_id","subj":"T65","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A66","pred":"fma_id","subj":"T66","obj":"http://purl.org/sig/ont/fma/fma62851"},{"id":"A67","pred":"fma_id","subj":"T67","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"A recent intriguing study found that CFTR dysfunction in platelets leads to aberrant transient receptor potential cation channel subfamily C member 6 (TRPC6)-dependent platelet activation, which was proposed as a major driver of CF-lung inflammation and impaired bacterial clearance [60]."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T18","span":{"begin":232,"end":236},"obj":"Body_part"}],"attributes":[{"id":"A18","pred":"uberon_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"A recent intriguing study found that CFTR dysfunction in platelets leads to aberrant transient receptor potential cation channel subfamily C member 6 (TRPC6)-dependent platelet activation, which was proposed as a major driver of CF-lung inflammation and impaired bacterial clearance [60]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T101","span":{"begin":229,"end":231},"obj":"Disease"},{"id":"T102","span":{"begin":237,"end":249},"obj":"Disease"}],"attributes":[{"id":"A101","pred":"mondo_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/MONDO_0009061"},{"id":"A102","pred":"mondo_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"A recent intriguing study found that CFTR dysfunction in platelets leads to aberrant transient receptor potential cation channel subfamily C member 6 (TRPC6)-dependent platelet activation, which was proposed as a major driver of CF-lung inflammation and impaired bacterial clearance [60]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T129","span":{"begin":0,"end":1},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T130","span":{"begin":37,"end":41},"obj":"http://purl.obolibrary.org/obo/PR_000001044"},{"id":"T131","span":{"begin":177,"end":187},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T132","span":{"begin":211,"end":212},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T133","span":{"begin":232,"end":236},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T134","span":{"begin":232,"end":236},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"}],"text":"A recent intriguing study found that CFTR dysfunction in platelets leads to aberrant transient receptor potential cation channel subfamily C member 6 (TRPC6)-dependent platelet activation, which was proposed as a major driver of CF-lung inflammation and impaired bacterial clearance [60]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T41","span":{"begin":114,"end":120},"obj":"Chemical"}],"attributes":[{"id":"A41","pred":"chebi_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_36916"}],"text":"A recent intriguing study found that CFTR dysfunction in platelets leads to aberrant transient receptor potential cation channel subfamily C member 6 (TRPC6)-dependent platelet activation, which was proposed as a major driver of CF-lung inflammation and impaired bacterial clearance [60]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"252","span":{"begin":85,"end":149},"obj":"Gene"},{"id":"253","span":{"begin":151,"end":156},"obj":"Gene"},{"id":"256","span":{"begin":37,"end":53},"obj":"Disease"},{"id":"257","span":{"begin":229,"end":249},"obj":"Disease"}],"attributes":[{"id":"A252","pred":"tao:has_database_id","subj":"252","obj":"Gene:7225"},{"id":"A253","pred":"tao:has_database_id","subj":"253","obj":"Gene:7225"},{"id":"A256","pred":"tao:has_database_id","subj":"256","obj":"MESH:D009461"},{"id":"A257","pred":"tao:has_database_id","subj":"257","obj":"MESH:D011014"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"A recent intriguing study found that CFTR dysfunction in platelets leads to aberrant transient receptor potential cation channel subfamily C member 6 (TRPC6)-dependent platelet activation, which was proposed as a major driver of CF-lung inflammation and impaired bacterial clearance [60]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T122","span":{"begin":37,"end":41},"obj":"http://purl.obolibrary.org/obo/GO_0005260"},{"id":"T123","span":{"begin":168,"end":187},"obj":"http://purl.obolibrary.org/obo/GO_0030168"},{"id":"T124","span":{"begin":237,"end":249},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"A recent intriguing study found that CFTR dysfunction in platelets leads to aberrant transient receptor potential cation channel subfamily C member 6 (TRPC6)-dependent platelet activation, which was proposed as a major driver of CF-lung inflammation and impaired bacterial clearance [60]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T49","span":{"begin":0,"end":288},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A recent intriguing study found that CFTR dysfunction in platelets leads to aberrant transient receptor potential cation channel subfamily C member 6 (TRPC6)-dependent platelet activation, which was proposed as a major driver of CF-lung inflammation and impaired bacterial clearance [60]."}