PMC:7556165 / 72748-73224
Annnotations
LitCovid-sample-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T198 | 20-27 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T199 | 159-166 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T200 | 179-190 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T201 | 207-214 | Chemical | denotes | insulin | http://purl.obolibrary.org/obo/CHEBI_145810 |
| T202 | 334-345 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
| T203 | 402-412 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
LitCovid-sample-PD-NCBITaxon
| Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
|---|---|---|---|---|---|
| T407 | 436-450 | Species | denotes | gut microbiome | NCBItxid:749906 |
LitCovid-sample-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T429 | 0-54 | Sentence | denotes | ACE2 is a multiform protein (Feng et al., 2010, 2011). |
| T430 | 55-245 | Sentence | denotes | As discussed above (section Structure of ACE2) its C-terminal domain is similar to collectrin, a kidney protein involved in amino acids trafficking and insulin secretion (Kuba et al., 2013). |
| T431 | 246-358 | Sentence | denotes | Alterations in ACE2 have been demonstrated in Hartnup’s disease due to a disturbance in amino acids homeostasis. |
| T432 | 359-476 | Sentence | denotes | Indeed, ACE2 has been proposed to modulate amino acid transport in bowel and gut microbiome (Hashimoto et al., 2012). |
LitCovid-sample-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T154 | 152-158 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
LitCovid-sample-Pubtator
| Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
|---|---|---|---|---|---|
| 1992 | 0-4 | Gene | denotes | ACE2 | Gene:59272 |
| 1993 | 96-100 | Gene | denotes | ACE2 | Gene:59272 |
| 1994 | 138-148 | Gene | denotes | collectrin | Gene:57393 |
| 1995 | 207-214 | Gene | denotes | insulin | Gene:3630 |
| 1996 | 261-265 | Gene | denotes | ACE2 | Gene:59272 |
| 1997 | 367-371 | Gene | denotes | ACE2 | Gene:59272 |
| 1998 | 436-450 | Species | denotes | gut microbiome | Tax:749906 |
| 1999 | 292-309 | Disease | denotes | Hartnup’s disease | MESH:D006250 |
LitCovid-sample-UniProt
| Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
|---|---|---|---|---|---|
| T6257 | 0-4 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
| T6258 | 96-100 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
| T6259 | 138-148 | Protein | denotes | collectrin | https://www.uniprot.org/uniprot/Q9HBJ8|https://www.uniprot.org/uniprot/Q9ESG4|https://www.uniprot.org/uniprot/Q9ESG3|https://www.uniprot.org/uniprot/Q6UW07|https://www.uniprot.org/uniprot/Q6AYY2|https://www.uniprot.org/uniprot/Q3UFF6|https://www.uniprot.org/uniprot/Q0VCT4|https://www.uniprot.org/uniprot/B2R9M1 |
| T6267 | 207-214 | Protein | denotes | insulin | https://www.uniprot.org/uniprot/Q9W7R2|https://www.uniprot.org/uniprot/Q9W653|https://www.uniprot.org/uniprot/Q9TSJ5|https://www.uniprot.org/uniprot/Q9TQY8|https://www.uniprot.org/uniprot/Q9TQY7|https://www.uniprot.org/uniprot/Q9PRR2|https://www.uniprot.org/uniprot/Q9PRR1|https://www.uniprot.org/uniprot/Q9NDE7|https://www.uniprot.org/uniprot/Q98TA8|https://www.uniprot.org/uniprot/Q91XI3|https://www.uniprot.org/uniprot/Q91479|https://www.uniprot.org/uniprot/Q91478|https://www.uniprot.org/uniprot/Q91477|https://www.uniprot.org/uniprot/Q8WNW6|https://www.uniprot.org/uniprot/Q8HXV2|https://www.uniprot.org/uniprot/Q6YK33|https://www.uniprot.org/uniprot/Q62587|https://www.uniprot.org/uniprot/Q5EEX2|https://www.uniprot.org/uniprot/Q53YX4|https://www.uniprot.org/uniprot/Q504H9|https://www.uniprot.org/uniprot/Q10995|https://www.uniprot.org/uniprot/P81881|https://www.uniprot.org/uniprot/P81423|https://www.uniprot.org/uniprot/P81025|https://www.uniprot.org/uniprot/P69048|https://www.uniprot.org/uniprot/P69047|https://www.uniprot.org/uniprot/P69046|https://www.uniprot.org/uniprot/P69045|https://www.uniprot.org/uniprot/P68992|https://www.uniprot.org/uniprot/P68991|https://www.uniprot.org/uniprot/P68990|https://www.uniprot.org/uniprot/P68989|https://www.uniprot.org/uniprot/P68988|https://www.uniprot.org/uniprot/P68987|https://www.uniprot.org/uniprot/P68245|https://www.uniprot.org/uniprot/P68243|https://www.uniprot.org/uniprot/P67974|https://www.uniprot.org/uniprot/P67973|https://www.uniprot.org/uniprot/P67972|https://www.uniprot.org/uniprot/P67971|https://www.uniprot.org/uniprot/P67970|https://www.uniprot.org/uniprot/P67969|https://www.uniprot.org/uniprot/P67968|https://www.uniprot.org/uniprot/P51463|https://www.uniprot.org/uniprot/P42633|https://www.uniprot.org/uniprot/P41522|https://www.uniprot.org/uniprot/P31887|https://www.uniprot.org/uniprot/P30410|https://www.uniprot.org/uniprot/P30407|https://www.uniprot.org/uniprot/P30406|https://www.uniprot.org/uniprot/P29335|https://www.uniprot.org/uniprot/P23187|https://www.uniprot.org/uniprot/P21563|https://www.uniprot.org/uniprot/P18109|https://www.uniprot.org/uniprot/P17715|https://www.uniprot.org/uniprot/P14806|https://www.uniprot.org/uniprot/P13190|https://www.uniprot.org/uniprot/P12708|https://www.uniprot.org/uniprot/P12705|https://www.uniprot.org/uniprot/P12704|https://www.uniprot.org/uniprot/P12703|https://www.uniprot.org/uniprot/P10604|https://www.uniprot.org/uniprot/P0C236|https://www.uniprot.org/uniprot/P09536|https://www.uniprot.org/uniprot/P09477|https://www.uniprot.org/uniprot/P09476|https://www.uniprot.org/uniprot/P07454|https://www.uniprot.org/uniprot/P07453|https://www.uniprot.org/uniprot/P06306|https://www.uniprot.org/uniprot/P04667|https://www.uniprot.org/uniprot/P01342|https://www.uniprot.org/uniprot/P01341|https://www.uniprot.org/uniprot/P01340|https://www.uniprot.org/uniprot/P01339|https://www.uniprot.org/uniprot/P01336|https://www.uniprot.org/uniprot/P01335|https://www.uniprot.org/uniprot/P01334|https://www.uniprot.org/uniprot/P01333|https://www.uniprot.org/uniprot/P01332|https://www.uniprot.org/uniprot/P01331|https://www.uniprot.org/uniprot/P01330|https://www.uniprot.org/uniprot/P01329|https://www.uniprot.org/uniprot/P01328|https://www.uniprot.org/uniprot/P01327|https://www.uniprot.org/uniprot/P01324|https://www.uniprot.org/uniprot/P01321|https://www.uniprot.org/uniprot/P01320|https://www.uniprot.org/uniprot/P01319|https://www.uniprot.org/uniprot/P01318|https://www.uniprot.org/uniprot/P01317|https://www.uniprot.org/uniprot/P01316|https://www.uniprot.org/uniprot/P01315|https://www.uniprot.org/uniprot/P01314|https://www.uniprot.org/uniprot/P01313|https://www.uniprot.org/uniprot/P01312|https://www.uniprot.org/uniprot/P01311|https://www.uniprot.org/uniprot/P01310|https://www.uniprot.org/uniprot/P01309|https://www.uniprot.org/uniprot/P01308|https://www.uniprot.org/uniprot/O73727|https://www.uniprot.org/uniprot/O42485|https://www.uniprot.org/uniprot/C0HJU0|https://www.uniprot.org/uniprot/C0HJT9|https://www.uniprot.org/uniprot/C0HJI4|https://www.uniprot.org/uniprot/C0HJI1 |
| T6372 | 261-265 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
| T6373 | 367-371 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
LitCovid-sample-PD-IDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T300 | 302-309 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | disease |
LitCovid-sample-PD-FMA
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T465 | 20-27 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T466 | 152-158 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T467 | 159-166 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T468 | 179-190 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
| T469 | 207-214 | Body_part | denotes | insulin | http://purl.org/sig/ont/fma/fma83365 |
| T470 | 334-345 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
| T471 | 402-412 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
| T472 | 426-431 | Body_part | denotes | bowel | http://purl.org/sig/ont/fma/fma7199 |
| T473 | 436-439 | Body_part | denotes | gut | http://purl.org/sig/ont/fma/fma7199 |
LitCovid-sample-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T430 | 292-309 | Disease | denotes | Hartnup’s disease | http://purl.obolibrary.org/obo/MONDO_0009324 |
LitCovid-sample-PD-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T142 | 152-158 | http://purl.obolibrary.org/obo/MAT_0000119 | denotes | kidney |
| T143 | 436-439 | http://purl.obolibrary.org/obo/MAT_0000043 | denotes | gut |
LitCovid-sample-PD-GO-BP-0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T156 | 207-224 | http://purl.obolibrary.org/obo/GO_0030073 | denotes | insulin secretion |
| T157 | 215-224 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
| T158 | 334-357 | http://purl.obolibrary.org/obo/GO_0080144 | denotes | amino acids homeostasis |
| T159 | 346-357 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
| T160 | 402-422 | http://purl.obolibrary.org/obo/GO_0006865 | denotes | amino acid transport |
| T161 | 413-422 | http://purl.obolibrary.org/obo/GO_0006810 | denotes | transport |
LitCovid-sample-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T161 | 207-224 | http://purl.obolibrary.org/obo/GO_0030073 | denotes | insulin secretion |
| T162 | 215-224 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
| T163 | 334-357 | http://purl.obolibrary.org/obo/GO_0080144 | denotes | amino acids homeostasis |
| T164 | 346-357 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
| T165 | 402-422 | http://purl.obolibrary.org/obo/GO_0006865 | denotes | amino acid transport |
| T166 | 413-422 | http://purl.obolibrary.org/obo/GO_0006810 | denotes | transport |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1992 | 0-4 | Gene | denotes | ACE2 | Gene:59272 |
| 1993 | 96-100 | Gene | denotes | ACE2 | Gene:59272 |
| 1994 | 138-148 | Gene | denotes | collectrin | Gene:57393 |
| 1995 | 207-214 | Gene | denotes | insulin | Gene:3630 |
| 1996 | 261-265 | Gene | denotes | ACE2 | Gene:59272 |
| 1997 | 367-371 | Gene | denotes | ACE2 | Gene:59272 |
| 1998 | 436-450 | Species | denotes | gut microbiome | Tax:749906 |
| 1999 | 292-309 | Disease | denotes | Hartnup’s disease | MESH:D006250 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T429 | 0-54 | Sentence | denotes | ACE2 is a multiform protein (Feng et al., 2010, 2011). |
| T430 | 55-245 | Sentence | denotes | As discussed above (section Structure of ACE2) its C-terminal domain is similar to collectrin, a kidney protein involved in amino acids trafficking and insulin secretion (Kuba et al., 2013). |
| T431 | 246-358 | Sentence | denotes | Alterations in ACE2 have been demonstrated in Hartnup’s disease due to a disturbance in amino acids homeostasis. |
| T432 | 359-476 | Sentence | denotes | Indeed, ACE2 has been proposed to modulate amino acid transport in bowel and gut microbiome (Hashimoto et al., 2012). |