PMC:7556165 / 63511-63827 JSONTXT

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    LitCovid-sample-PD-NCBITaxon

    {"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T361","span":{"begin":157,"end":167},"obj":"Species"},{"id":"T362","span":{"begin":157,"end":161},"obj":"Species"},{"id":"T363","span":{"begin":176,"end":186},"obj":"Species"},{"id":"T364","span":{"begin":176,"end":180},"obj":"Species"}],"attributes":[{"id":"A361","pred":"ncbi_taxonomy_id","subj":"T361","obj":"NCBItxid:2697049"},{"id":"A362","pred":"ncbi_taxonomy_id","subj":"T362","obj":"NCBItxid:694009"},{"id":"A363","pred":"ncbi_taxonomy_id","subj":"T363","obj":"NCBItxid:2697049"},{"id":"A364","pred":"ncbi_taxonomy_id","subj":"T364","obj":"NCBItxid:694009"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-sample-sentences

    {"project":"LitCovid-sample-sentences","denotations":[{"id":"T379","span":{"begin":61,"end":168},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-sample-Pubtator

    {"project":"LitCovid-sample-Pubtator","denotations":[{"id":"1734","span":{"begin":88,"end":92},"obj":"Gene"},{"id":"1735","span":{"begin":157,"end":167},"obj":"Species"},{"id":"1746","span":{"begin":293,"end":298},"obj":"Gene"},{"id":"1750","span":{"begin":176,"end":196},"obj":"Disease"}],"attributes":[{"id":"A1734","pred":"pubann:denotes","subj":"1734","obj":"Gene:59272"},{"id":"A1735","pred":"pubann:denotes","subj":"1735","obj":"Tax:2697049"},{"id":"A1746","pred":"pubann:denotes","subj":"1746","obj":"Gene:114548"},{"id":"A1750","pred":"pubann:denotes","subj":"1750","obj":"MESH:C000657245"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-sample-UniProt

    {"project":"LitCovid-sample-UniProt","denotations":[{"id":"T5926","span":{"begin":88,"end":92},"obj":"Protein"}],"attributes":[{"id":"A5926","pred":"uniprot_id","subj":"T5926","obj":"https://www.uniprot.org/uniprot/Q9UFZ6"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-sample-PD-IDO

    {"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T255","span":{"begin":187,"end":196},"obj":"http://purl.obolibrary.org/obo/IDO_0000586"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-sample-PD-FMA

    {"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T429","span":{"begin":138,"end":146},"obj":"Body_part"},{"id":"T430","span":{"begin":247,"end":258},"obj":"Body_part"}],"attributes":[{"id":"A429","pred":"fma_id","subj":"T429","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A430","pred":"fma_id","subj":"T430","obj":"http://purl.org/sig/ont/fma/fma63261"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-sample-PD-MONDO

    {"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T371","span":{"begin":157,"end":167},"obj":"Disease"},{"id":"T372","span":{"begin":157,"end":161},"obj":"Disease"},{"id":"T373","span":{"begin":176,"end":186},"obj":"Disease"},{"id":"T374","span":{"begin":176,"end":180},"obj":"Disease"},{"id":"T375","span":{"begin":187,"end":196},"obj":"Disease"}],"attributes":[{"id":"A371","pred":"mondo_id","subj":"T371","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A372","pred":"mondo_id","subj":"T372","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A373","pred":"mondo_id","subj":"T373","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A374","pred":"mondo_id","subj":"T374","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A375","pred":"mondo_id","subj":"T375","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-sample-PD-GO-BP-0

    {"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T131","span":{"begin":266,"end":275},"obj":"http://purl.obolibrary.org/obo/GO_0039707"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-sample-PD-HP

    {"project":"LitCovid-sample-PD-HP","denotations":[{"id":"T66","span":{"begin":138,"end":152},"obj":"Phenotype"}],"attributes":[{"id":"A66","pred":"hp_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/HP_0033041"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-sample-GO-BP

    {"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T132","span":{"begin":198,"end":208},"obj":"http://purl.obolibrary.org/obo/GO_0070269"},{"id":"T133","span":{"begin":266,"end":275},"obj":"http://purl.obolibrary.org/obo/GO_0039707"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T69","span":{"begin":138,"end":152},"obj":"Phenotype"}],"attributes":[{"id":"A69","pred":"hp_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/HP_0033041"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"1734","span":{"begin":88,"end":92},"obj":"Gene"},{"id":"1735","span":{"begin":157,"end":167},"obj":"Species"},{"id":"1746","span":{"begin":293,"end":298},"obj":"Gene"},{"id":"1750","span":{"begin":176,"end":196},"obj":"Disease"}],"attributes":[{"id":"A1734","pred":"tao:has_database_id","subj":"1734","obj":"Gene:59272"},{"id":"A1735","pred":"tao:has_database_id","subj":"1735","obj":"Tax:2697049"},{"id":"A1746","pred":"tao:has_database_id","subj":"1746","obj":"Gene:114548"},{"id":"A1750","pred":"tao:has_database_id","subj":"1750","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T379","span":{"begin":61,"end":168},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).\nFIGURE 9 Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p"}