7; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9).
FIGURE 9  Possible role of ACE2 in the molecular mechanisms involved in the “cytokine storm” of SARS-CoV-2. In the SARS-CoV-2 infection, pyroptosis has been demonstrated to be active in macrophages, being viroporin 3a a trigger for NLRP3 with subsequent p