PMC:7556165 / 54021-56175
Annnotations
LitCovid-sample-PD-NCBITaxon
Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
---|---|---|---|---|---|
T332 | 48-56 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T333 | 1025-1033 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T334 | 1867-1875 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T335 | 1962-1972 | Species | denotes | SARS-CoV-2 | NCBItxid:2697049 |
T336 | 1962-1966 | Species | denotes | SARS | NCBItxid:694009 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T336 | 0-240 | Sentence | denotes | Epidemiological data consistently show that the COVID-19 patients at highest risk of a poor prognosis are males older than 60 years with chronic underlying diseases, mostly hypertension, cardiovascular diseases and type-2 diabetes mellitus. |
T337 | 241-423 | Sentence | denotes | Clinical reports have been rapidly delivered from all over the world, and meta-analyses assessing the prevalence of comorbidities and their impact on prognosis are already available. |
T338 | 424-671 | Sentence | denotes | A meta-analysis pooling data from seven studies following a total number of 1,576 infected patients from hospitals in China found that the most prevalent comorbidities were hypertension (21.1%), diabetes (9.7%), and cardiovascular diseases (8.4%). |
T339 | 672-880 | Sentence | denotes | These increased the risk of developing a more serious disease (i.e., requiring intensive care treatment), with odds ratios ranging from 2.4 (hypertension) to 3.4 (cardiovascular disease) (Yang et al., 2020b). |
T340 | 881-1156 | Sentence | denotes | These findings have been confirmed in the analysis performed by the Chinese Center for Disease Control and Prevention in a huge sample of 72314 COVID-19 cases (Epidemiology Working Group for Ncip Epidemic Response and Chinese Center for Disease Control and Prevention, 2020). |
T341 | 1157-1310 | Sentence | denotes | A study with 1591 Italian patients, similarly, reported a significant association between hypertension and mortality in Intensive Care Unit (63 vs. 40%). |
T342 | 1311-1455 | Sentence | denotes | This series reported an even higher prevalence of hypertension (49%), diabetes (17%), and cardiovascular disease (21%) (Grasselli et al., 2020). |
T343 | 1456-1644 | Sentence | denotes | Diabetes has been reported to predict the occurrence of ARDS (HR = 1.44), acute kidney injury (HR = 3.01), septic shock (HR = 1.95), and all-cause mortality (HR = 1.70) (Zhu et al., 2020). |
T344 | 1645-1803 | Sentence | denotes | Notably, poor glycemic control was significantly associated with worse clinical outcomes, namely multi-organ injuries and higher mortality (Zhu et al., 2020). |
T345 | 1804-1885 | Sentence | denotes | Obesity has also emerged as an important factor in determining COVID-19 severity. |
T346 | 1886-2154 | Sentence | denotes | Indeed, obesity was more frequent in patients admitted to critical care for SARS-CoV-2 as compared to the general population; moreover, the BMI was positively related to the need for invasive mechanical ventilation and mortality (Drucker, 2020; Simonnet et al., 2020). |
LitCovid-sample-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T140 | 1536-1542 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
T141 | 1748-1753 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062 |
LitCovid-sample-Pubtator
Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
---|---|---|---|---|---|
1536 | 57-65 | Species | denotes | patients | Tax:9606 |
1537 | 515-523 | Species | denotes | patients | Tax:9606 |
1538 | 1183-1191 | Species | denotes | patients | Tax:9606 |
1539 | 1923-1931 | Species | denotes | patients | Tax:9606 |
1540 | 1962-1972 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
1541 | 48-56 | Disease | denotes | COVID-19 | MESH:C000657245 |
1542 | 173-185 | Disease | denotes | hypertension | MESH:D006973 |
1543 | 187-210 | Disease | denotes | cardiovascular diseases | MESH:D002318 |
1544 | 215-239 | Disease | denotes | type-2 diabetes mellitus | MESH:D003924 |
1545 | 506-514 | Disease | denotes | infected | MESH:D007239 |
1546 | 597-609 | Disease | denotes | hypertension | MESH:D006973 |
1547 | 619-627 | Disease | denotes | diabetes | MESH:D003920 |
1548 | 640-663 | Disease | denotes | cardiovascular diseases | MESH:D002318 |
1549 | 813-825 | Disease | denotes | hypertension | MESH:D006973 |
1550 | 835-857 | Disease | denotes | cardiovascular disease | MESH:D002318 |
1551 | 1025-1033 | Disease | denotes | COVID-19 | MESH:C000657245 |
1552 | 1247-1259 | Disease | denotes | hypertension | MESH:D006973 |
1553 | 1264-1273 | Disease | denotes | mortality | MESH:D003643 |
1554 | 1361-1373 | Disease | denotes | hypertension | MESH:D006973 |
1555 | 1381-1389 | Disease | denotes | diabetes | MESH:D003920 |
1556 | 1401-1423 | Disease | denotes | cardiovascular disease | MESH:D002318 |
1557 | 1456-1464 | Disease | denotes | Diabetes | MESH:D003920 |
1558 | 1512-1516 | Disease | denotes | ARDS | MESH:D012128 |
1559 | 1530-1549 | Disease | denotes | acute kidney injury | MESH:D058186 |
1560 | 1563-1575 | Disease | denotes | septic shock | MESH:D012772 |
1561 | 1603-1612 | Disease | denotes | mortality | MESH:D003643 |
1562 | 1774-1783 | Disease | denotes | mortality | MESH:D003643 |
1563 | 1867-1875 | Disease | denotes | COVID-19 | MESH:C000657245 |
1564 | 1894-1901 | Disease | denotes | obesity | MESH:D009765 |
1565 | 2105-2114 | Disease | denotes | mortality | MESH:D003643 |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T207 | 156-164 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | diseases |
T208 | 202-210 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | diseases |
T209 | 506-514 | http://purl.obolibrary.org/obo/IDO_0000586 | denotes | infected |
T210 | 655-663 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | diseases |
T211 | 726-733 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | disease |
T212 | 850-857 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | disease |
T213 | 968-975 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | Disease |
T214 | 1118-1125 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | Disease |
T215 | 1416-1423 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | disease |
T216 | 1748-1753 | http://purl.obolibrary.org/obo/OBI_0100026 | denotes | organ |
LitCovid-sample-PD-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T397 | 1536-1542 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
T398 | 1748-1753 | Body_part | denotes | organ | http://purl.org/sig/ont/fma/fma67498 |
LitCovid-sample-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T296 | 48-56 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T297 | 173-210 | Disease | denotes | hypertension, cardiovascular diseases | http://purl.obolibrary.org/obo/MONDO_0001302 |
T298 | 215-239 | Disease | denotes | type-2 diabetes mellitus | http://purl.obolibrary.org/obo/MONDO_0005148 |
T299 | 597-609 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
T300 | 619-627 | Disease | denotes | diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
T301 | 640-663 | Disease | denotes | cardiovascular diseases | http://purl.obolibrary.org/obo/MONDO_0004995 |
T302 | 813-825 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
T303 | 835-857 | Disease | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0004995 |
T304 | 1025-1033 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T305 | 1247-1259 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
T306 | 1361-1373 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
T307 | 1381-1389 | Disease | denotes | diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
T308 | 1401-1423 | Disease | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0004995 |
T309 | 1456-1464 | Disease | denotes | Diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
T310 | 1512-1516 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T311 | 1530-1549 | Disease | denotes | acute kidney injury | http://purl.obolibrary.org/obo/MONDO_0002492 |
T312 | 1804-1811 | Disease | denotes | Obesity | http://purl.obolibrary.org/obo/MONDO_0011122 |
T313 | 1867-1875 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T314 | 1894-1901 | Disease | denotes | obesity | http://purl.obolibrary.org/obo/MONDO_0011122 |
T315 | 1962-1972 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T316 | 1962-1966 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-sample-PD-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T128 | 106-111 | http://purl.obolibrary.org/obo/MAT_0000029 | denotes | males |
T129 | 1536-1542 | http://purl.obolibrary.org/obo/MAT_0000119 | denotes | kidney |
LitCovid-sample-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T42 | 173-185 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T43 | 187-210 | Phenotype | denotes | cardiovascular diseases | http://purl.obolibrary.org/obo/HP_0001626 |
T44 | 222-239 | Phenotype | denotes | diabetes mellitus | http://purl.obolibrary.org/obo/HP_0000819 |
T45 | 597-609 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T46 | 640-663 | Phenotype | denotes | cardiovascular diseases | http://purl.obolibrary.org/obo/HP_0001626 |
T47 | 813-825 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T48 | 835-857 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
T49 | 1247-1259 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T50 | 1361-1373 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T51 | 1401-1423 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
T52 | 1530-1549 | Phenotype | denotes | acute kidney injury | http://purl.obolibrary.org/obo/HP_0001919 |
T53 | 1570-1575 | Phenotype | denotes | shock | http://purl.obolibrary.org/obo/HP_0031273 |
T54 | 1804-1811 | Phenotype | denotes | Obesity | http://purl.obolibrary.org/obo/HP_0001513 |
T55 | 1894-1901 | Phenotype | denotes | obesity | http://purl.obolibrary.org/obo/HP_0001513 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T45 | 173-185 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T46 | 187-210 | Phenotype | denotes | cardiovascular diseases | http://purl.obolibrary.org/obo/HP_0001626 |
T47 | 222-239 | Phenotype | denotes | diabetes mellitus | http://purl.obolibrary.org/obo/HP_0000819 |
T48 | 597-609 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T49 | 640-663 | Phenotype | denotes | cardiovascular diseases | http://purl.obolibrary.org/obo/HP_0001626 |
T50 | 813-825 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T51 | 835-857 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
T52 | 1247-1259 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T53 | 1361-1373 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T54 | 1401-1423 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
T55 | 1530-1549 | Phenotype | denotes | acute kidney injury | http://purl.obolibrary.org/obo/HP_0001919 |
T56 | 1570-1575 | Phenotype | denotes | shock | http://purl.obolibrary.org/obo/HP_0031273 |
T57 | 1804-1811 | Phenotype | denotes | Obesity | http://purl.obolibrary.org/obo/HP_0001513 |
T58 | 1894-1901 | Phenotype | denotes | obesity | http://purl.obolibrary.org/obo/HP_0001513 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1536 | 57-65 | Species | denotes | patients | Tax:9606 |
1537 | 515-523 | Species | denotes | patients | Tax:9606 |
1538 | 1183-1191 | Species | denotes | patients | Tax:9606 |
1539 | 1923-1931 | Species | denotes | patients | Tax:9606 |
1540 | 1962-1972 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
1541 | 48-56 | Disease | denotes | COVID-19 | MESH:C000657245 |
1542 | 173-185 | Disease | denotes | hypertension | MESH:D006973 |
1543 | 187-210 | Disease | denotes | cardiovascular diseases | MESH:D002318 |
1544 | 215-239 | Disease | denotes | type-2 diabetes mellitus | MESH:D003924 |
1545 | 506-514 | Disease | denotes | infected | MESH:D007239 |
1546 | 597-609 | Disease | denotes | hypertension | MESH:D006973 |
1547 | 619-627 | Disease | denotes | diabetes | MESH:D003920 |
1548 | 640-663 | Disease | denotes | cardiovascular diseases | MESH:D002318 |
1549 | 813-825 | Disease | denotes | hypertension | MESH:D006973 |
1550 | 835-857 | Disease | denotes | cardiovascular disease | MESH:D002318 |
1551 | 1025-1033 | Disease | denotes | COVID-19 | MESH:C000657245 |
1552 | 1247-1259 | Disease | denotes | hypertension | MESH:D006973 |
1553 | 1264-1273 | Disease | denotes | mortality | MESH:D003643 |
1554 | 1361-1373 | Disease | denotes | hypertension | MESH:D006973 |
1555 | 1381-1389 | Disease | denotes | diabetes | MESH:D003920 |
1556 | 1401-1423 | Disease | denotes | cardiovascular disease | MESH:D002318 |
1557 | 1456-1464 | Disease | denotes | Diabetes | MESH:D003920 |
1558 | 1512-1516 | Disease | denotes | ARDS | MESH:D012128 |
1559 | 1530-1549 | Disease | denotes | acute kidney injury | MESH:D058186 |
1560 | 1563-1575 | Disease | denotes | septic shock | MESH:D012772 |
1561 | 1603-1612 | Disease | denotes | mortality | MESH:D003643 |
1562 | 1774-1783 | Disease | denotes | mortality | MESH:D003643 |
1563 | 1867-1875 | Disease | denotes | COVID-19 | MESH:C000657245 |
1564 | 1894-1901 | Disease | denotes | obesity | MESH:D009765 |
1565 | 2105-2114 | Disease | denotes | mortality | MESH:D003643 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T336 | 0-240 | Sentence | denotes | Epidemiological data consistently show that the COVID-19 patients at highest risk of a poor prognosis are males older than 60 years with chronic underlying diseases, mostly hypertension, cardiovascular diseases and type-2 diabetes mellitus. |
T337 | 241-423 | Sentence | denotes | Clinical reports have been rapidly delivered from all over the world, and meta-analyses assessing the prevalence of comorbidities and their impact on prognosis are already available. |
T338 | 424-671 | Sentence | denotes | A meta-analysis pooling data from seven studies following a total number of 1,576 infected patients from hospitals in China found that the most prevalent comorbidities were hypertension (21.1%), diabetes (9.7%), and cardiovascular diseases (8.4%). |
T339 | 672-880 | Sentence | denotes | These increased the risk of developing a more serious disease (i.e., requiring intensive care treatment), with odds ratios ranging from 2.4 (hypertension) to 3.4 (cardiovascular disease) (Yang et al., 2020b). |
T340 | 881-1156 | Sentence | denotes | These findings have been confirmed in the analysis performed by the Chinese Center for Disease Control and Prevention in a huge sample of 72314 COVID-19 cases (Epidemiology Working Group for Ncip Epidemic Response and Chinese Center for Disease Control and Prevention, 2020). |
T341 | 1157-1310 | Sentence | denotes | A study with 1591 Italian patients, similarly, reported a significant association between hypertension and mortality in Intensive Care Unit (63 vs. 40%). |
T342 | 1311-1455 | Sentence | denotes | This series reported an even higher prevalence of hypertension (49%), diabetes (17%), and cardiovascular disease (21%) (Grasselli et al., 2020). |
T343 | 1456-1644 | Sentence | denotes | Diabetes has been reported to predict the occurrence of ARDS (HR = 1.44), acute kidney injury (HR = 3.01), septic shock (HR = 1.95), and all-cause mortality (HR = 1.70) (Zhu et al., 2020). |
T344 | 1645-1803 | Sentence | denotes | Notably, poor glycemic control was significantly associated with worse clinical outcomes, namely multi-organ injuries and higher mortality (Zhu et al., 2020). |
T345 | 1804-1885 | Sentence | denotes | Obesity has also emerged as an important factor in determining COVID-19 severity. |
T346 | 1886-2154 | Sentence | denotes | Indeed, obesity was more frequent in patients admitted to critical care for SARS-CoV-2 as compared to the general population; moreover, the BMI was positively related to the need for invasive mechanical ventilation and mortality (Drucker, 2020; Simonnet et al., 2020). |