PMC:7556165 / 4685-5131 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7556165","sourcedb":"PMC","sourceid":"7556165","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7556165","text":"Human Angiotensin-converting enzyme (ACE) belongs to the M2 gluzincin family of metalloproteinases and (Ehlers and Riordan, 1989; Masuyer et al., 2014) exists in two forms, namely somatic ACE (sACE) and germinal ACE (tACE). Both are derived from the same gene, controlled by alternative promotors. sACE is an integral membrane protein, which can be also cleaved by ACE secretases to produce a circulating form of the enzyme (Natesh et al., 2003).","tracks":[{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T20","span":{"begin":6,"end":35},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T21","span":{"begin":37,"end":40},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T22","span":{"begin":188,"end":191},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T23","span":{"begin":212,"end":215},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T24","span":{"begin":365,"end":368},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A20","pred":"meddra_id","subj":"T20","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"},{"id":"A21","pred":"meddra_id","subj":"T21","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"},{"id":"A22","pred":"meddra_id","subj":"T22","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"},{"id":"A23","pred":"meddra_id","subj":"T23","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"},{"id":"A24","pred":"meddra_id","subj":"T24","obj":"http://purl.bioontology.org/ontology/MEDDRA/10050289"},{"subj":"T20","pred":"source","obj":"LitCovid-sample-MedDRA"},{"subj":"T21","pred":"source","obj":"LitCovid-sample-MedDRA"},{"subj":"T22","pred":"source","obj":"LitCovid-sample-MedDRA"},{"subj":"T23","pred":"source","obj":"LitCovid-sample-MedDRA"},{"subj":"T24","pred":"source","obj":"LitCovid-sample-MedDRA"}]},{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T15","span":{"begin":6,"end":17},"obj":"Chemical"},{"id":"T16","span":{"begin":327,"end":334},"obj":"Chemical"}],"attributes":[{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_2719"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"subj":"T15","pred":"source","obj":"LitCovid-sample-CHEBI"},{"subj":"T16","pred":"source","obj":"LitCovid-sample-CHEBI"}]},{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T28","span":{"begin":0,"end":5},"obj":"Species"}],"attributes":[{"id":"A28","pred":"ncbi_taxonomy_id","subj":"T28","obj":"NCBItxid:9606"},{"subj":"T28","pred":"source","obj":"LitCovid-sample-PD-NCBITaxon"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}]},{"project":"LitCovid-sample-sentences","denotations":[{"id":"T34","span":{"begin":0,"end":223},"obj":"Sentence"},{"id":"T35","span":{"begin":224,"end":446},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T34","pred":"source","obj":"LitCovid-sample-sentences"},{"subj":"T35","pred":"source","obj":"LitCovid-sample-sentences"}]},{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"167","span":{"begin":6,"end":35},"obj":"Gene"},{"id":"168","span":{"begin":37,"end":40},"obj":"Gene"},{"id":"169","span":{"begin":212,"end":215},"obj":"Gene"},{"id":"170","span":{"begin":217,"end":221},"obj":"Gene"},{"id":"171","span":{"begin":365,"end":368},"obj":"Gene"},{"id":"172","span":{"begin":188,"end":191},"obj":"Gene"},{"id":"173","span":{"begin":318,"end":326},"obj":"Gene"},{"id":"174","span":{"begin":0,"end":5},"obj":"Species"},{"id":"175","span":{"begin":60,"end":69},"obj":"Chemical"}],"attributes":[{"id":"A169","pred":"pubann:denotes","subj":"169","obj":"Gene:1636"},{"id":"A171","pred":"pubann:denotes","subj":"171","obj":"Gene:1636"},{"id":"A174","pred":"pubann:denotes","subj":"174","obj":"Tax:9606"},{"id":"A168","pred":"pubann:denotes","subj":"168","obj":"Gene:1636"},{"id":"A173","pred":"pubann:denotes","subj":"173","obj":"Gene:43740571"},{"id":"A170","pred":"pubann:denotes","subj":"170","obj":"Gene:6868"},{"id":"A167","pred":"pubann:denotes","subj":"167","obj":"Gene:1636"},{"id":"A172","pred":"pubann:denotes","subj":"172","obj":"Gene:1636"},{"subj":"167","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"168","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"169","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"170","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"171","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"172","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"173","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"174","pred":"source","obj":"LitCovid-sample-Pubtator"},{"subj":"175","pred":"source","obj":"LitCovid-sample-Pubtator"}]},{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T560","span":{"begin":6,"end":35},"obj":"Protein"},{"id":"T592","span":{"begin":37,"end":40},"obj":"Protein"},{"id":"T617","span":{"begin":188,"end":191},"obj":"Protein"},{"id":"T642","span":{"begin":212,"end":215},"obj":"Protein"},{"id":"T667","span":{"begin":318,"end":334},"obj":"Protein"},{"id":"T764","span":{"begin":365,"end":368},"obj":"Protein"}],"attributes":[{"id":"A560","pred":"uniprot_id","subj":"T560","obj":"https://www.uniprot.org/uniprot/Q9VJV3"},{"id":"A561","pred":"uniprot_id","subj":"T560","obj":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