PMC:7556165 / 3567-3912 JSONTXT

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2003 ACE2 was also identified as the initial cellular target of the SARS-CoV virus, since its spike glycoprotein was found to be a high affinity ligand of membrane ACE2. Similar properties are shared by SARS-CoV-2 virus, and the huge impact of the recent COVID-19 pandemic has triggered novel interest in ACE2, particularly in the regulation of"}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T13","span":{"begin":78,"end":83},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T14","span":{"begin":215,"end":220},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":" 2003 ACE2 was also identified as the initial cellular target of the SARS-CoV virus, since its spike glycoprotein was found to be a high affinity ligand of membrane ACE2. Similar properties are shared by SARS-CoV-2 virus, and the huge impact of the recent COVID-19 pandemic has triggered novel interest in ACE2, particularly in the regulation of"}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T16","span":{"begin":101,"end":113},"obj":"Body_part"}],"attributes":[{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma62925"}],"text":" 2003 ACE2 was also identified as the initial cellular target of the SARS-CoV virus, since its spike glycoprotein was found to be a high affinity ligand of membrane ACE2. Similar properties are shared by SARS-CoV-2 virus, and the huge impact of the recent COVID-19 pandemic has triggered novel interest in ACE2, particularly in the regulation of"}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T27","span":{"begin":69,"end":77},"obj":"Disease"},{"id":"T28","span":{"begin":69,"end":73},"obj":"Disease"},{"id":"T29","span":{"begin":204,"end":214},"obj":"Disease"},{"id":"T30","span":{"begin":204,"end":208},"obj":"Disease"},{"id":"T31","span":{"begin":256,"end":264},"obj":"Disease"}],"attributes":[{"id":"A27","pred":"mondo_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A28","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A30","pred":"mondo_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A31","pred":"mondo_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":" 2003 ACE2 was also identified as the initial cellular target of the SARS-CoV virus, since its spike glycoprotein was found to be a high affinity ligand of membrane ACE2. Similar properties are shared by SARS-CoV-2 virus, and the huge impact of the recent COVID-19 pandemic has triggered novel interest in ACE2, particularly in the regulation of"}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T8","span":{"begin":332,"end":342},"obj":"http://purl.obolibrary.org/obo/GO_0065007"}],"text":" 2003 ACE2 was also identified as the initial cellular target of the SARS-CoV virus, since its spike glycoprotein was found to be a high affinity ligand of membrane ACE2. Similar properties are shared by SARS-CoV-2 virus, and the huge impact of the recent COVID-19 pandemic has triggered novel interest in ACE2, particularly in the regulation of"}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T8","span":{"begin":332,"end":342},"obj":"http://purl.obolibrary.org/obo/GO_0065007"}],"text":" 2003 ACE2 was also identified as the initial cellular target of the SARS-CoV virus, since its spike glycoprotein was found to be a high affinity ligand of membrane ACE2. Similar properties are shared by SARS-CoV-2 virus, and the huge impact of the recent COVID-19 pandemic has triggered novel interest in ACE2, particularly in the regulation of"}

{"project":"LitCovid-PubTator","denotations":[{"id":"128","span":{"begin":6,"end":10},"obj":"Gene"},{"id":"129","span":{"begin":165,"end":169},"obj":"Gene"},{"id":"130","span":{"begin":306,"end":310},"obj":"Gene"},{"id":"131","span":{"begin":156,"end":164},"obj":"Gene"},{"id":"132","span":{"begin":69,"end":77},"obj":"Species"},{"id":"133","span":{"begin":204,"end":214},"obj":"Species"},{"id":"135","span":{"begin":256,"end":264},"obj":"Disease"}],"attributes":[{"id":"A128","pred":"tao:has_database_id","subj":"128","obj":"Gene:59272"},{"id":"A129","pred":"tao:has_database_id","subj":"129","obj":"Gene:59272"},{"id":"A130","pred":"tao:has_database_id","subj":"130","obj":"Gene:59272"},{"id":"A131","pred":"tao:has_database_id","subj":"131","obj":"Gene:43740571"},{"id":"A132","pred":"tao:has_database_id","subj":"132","obj":"Tax:694009"},{"id":"A133","pred":"tao:has_database_id","subj":"133","obj":"Tax:2697049"},{"id":"A135","pred":"tao:has_database_id","subj":"135","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" 2003 ACE2 was also identified as the initial cellular target of the SARS-CoV virus, since its spike glycoprotein was found to be a high affinity ligand of membrane ACE2. Similar properties are shared by SARS-CoV-2 virus, and the huge impact of the recent COVID-19 pandemic has triggered novel interest in ACE2, particularly in the regulation of"}